[Basal cell carcinoma of the perianal region: a case report and literature review]. / Carcinoma basocelular de la región perianal: reporte de un caso y revisión de la literatura.

The literature reports an annual incidence of 5,900 cases of anal cancer in the developed countries. These involve three different anatomic zones: carcinoma of the anal canal, perianal carcinoma (formerly known as carcinoma of the anal margin, located at a distance of less than 5cm from the anal margin), and carcinoma of the perianal skin (at a distance greater than 5cm from the anal margin). Basal cell carcinoma of the perianal region is an uncommon tumor (0.27% of all diagnosed basal cell carcinomas) that in the majority of cases is treated by resection with disease-free margins. It must be differentiated from the basaloid and epidermoid variants of carcinoma, given that it has good outcome and its spread potential is practically null.

Fiebre persistente, pancitopenia y esplenomegalia en un portador detrasplante cardíaco como manifestaciones de leishmaniasis visceral / Persistent fever, pancytopenia and spleen enlargement in a heart transplant carrier as presentation of visceral leishmaniasis

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Desaparición de una masa valvular aórtica con anticoagulación / Aortic valvular mass disappearance with anticoagulation

Describimos el caso de una mujer joven seguida en la consulta de Neurología por episodios de vértigo, pérdida de campo visual y síncopes. La batería de pruebas analíticas solicitada resultó anodina, descartándose un substrato trombofílico. Las pruebas de imagen pusieron de manifiesto la presencia de lesiones isquémicas occipitales de probable origen microembólico o vasculítico. Ante la repetición de nuevos episodios neurológicos focales se practicó una ecocardiografía transtorácica seguida de un ETE. Esta última constató la presencia de una masa valvular aórtica asociada a regurgitación significativa. Analizando las características ecocardiográficas de la masa, así como el contexto clínico de la paciente, se llegó al diagnóstico de probable fibroelastoma papilar aórtico y se pautó anticoagulación oral. Un año más tarde hemos comprobado la desaparición de la masa valvular aórtica así como la disminución del grado de regurgitación (AU)

Molecular epidemiology of hepatitis B virus in Afro-Venezuelan populations.

Hepatitis B virus (HBV) infection among Venezuelan populations of African origin was analyzed. These populations exhibited lower HBV prevalence than the one found in the African continent. Sequence analysis of 6 isolates showed that 3 belonged to genotype F, while the 3 others were HBV genotype A. HBV genotype A was more common in the Afro-Venezuelan groups than in the general Venezuelan population. This might reflect the introduction of genotype A during the slavery period. The absence of the African genotype E among these isolates supports the hypothesis of a recent origin for this HBV genotype. HBV genotype F has already been introduced to these relatively isolated communities.

[The revised PEDINFUS computer program for total and added parenteral nutrition in children]. / Das weiterentwickelte Computerprogramm PEDINFUS für die totale und additive parenterale Ernährung von Kindern.

The computer program PEDINFUS, first described in 1991, has been fundamentally revised and further developed. The area of application has been considerably widened as additive parenteral nutrition has been included and the group of newborn and preterm infants has been taken into account. Consequently, the program can be used for children of all age groups. In addition, the program has a graphical user interface and can be used on several hardware platforms. The flexibility of the program has also been increased to a considerable degree. Now the nutrient amounts per kilogram per day, the limits of the laboratory values, the combination of enteral food and infusion solutions, and the already drawn-up infusion plans can be changed at liberty. Considerably more matters of clinical interest accompanying parenteral nutrition have been integrated in the program. Further plausibility controls have also been introduced to achieve greater certainty in the calculation of the infusion solutions. In consequence, the preconditions for ensuring and controlling the quality of infusion therapy regimens can be established on an improved level.