ABSTRACT
OBJECTIVE: Describe the usability, actionability and understanding of videos to promote exercise at home online during the COVID-19 pandemic, analyzing the characteristics of the population, their satisfaction, adherence and barriers to physical exercise. MATERIAL AND METHODS: A descriptive, non-experimental and cross-sectional observational design study, with a quantitative approach. Home-based videos of physical exercise and education about pain were created for people over 60 years old and distributed in the Metropolitan Region (Chile) during the months of October to December 2020. Participants had to use these videos independently at home during 4 weeks. A sample who received these videos were then voluntarily surveyed. RESULTS: Thirty-four participants rated the videos as understandable and actionable. Usability was lower in people who perceived a lower level of technological management. Average adherence was 2 days a week for 2.5 weeks. The main perceived barrier was the lack of will, which showed a greater tendency in people who performed physical exercise in a group way before the restrictions due to the COVID-19 pandemic. CONCLUSIONS: The videos were well evaluated by the elderly population, however the technological gap can be a limitation to favor an easy and simple use. Among the strategies, interventions that favor social interaction should be considered to promote interpersonal motivation, especially in people who prefer group modalities of exercise.
Subject(s)
COVID-19 , Exercise , Health Promotion , Video Recording , Aged , COVID-19/epidemiology , Chile/epidemiology , Cross-Sectional Studies , Humans , PandemicsABSTRACT
Objetivo: Describir la usabilidad, la accionabilidad y la comprensión de videos para promover el ejercicio en el hogar de manera online durante la pandemia COVID-19, analizando las características de la población, su satisfacción, adherencia y barreras para realizar ejercicio físico.Material y métodos: Estudio de diseño observacional descriptivo, no experimental y transversal, con enfoque cuantitativo. Se crearon videos de ejercicio físico y educación sobre dolor para personas mayores de 60 años, y fueron distribuidos en la Región Metropolitana (Chile) durante los meses de octubre a diciembre del 2020. La intervención consistió en el uso independiente en el hogar de estos videos, y tuvo una duración de 4 semanas. Luego, una muestra que recibió estos videos contestó una encuesta voluntariamente.Resultados: Treinta y cuatro participantes evaluaron los videos como comprensibles y accionables. La usabilidad fue menor en las personas que percibían un nivel de manejo tecnológico menor. La adherencia promedio fue de 2 días a la semana durante 2,5 semanas. La principal barrera percibida fue la falta de voluntad, la cual mostró una mayor tendencia en las personas que realizaban ejercicio físico de manera grupal antes de las restricciones por la pandemia COVID-19.Conclusiones: Los videos desarrollados fueron una herramienta bien evaluada por parte de la población mayor, sin embargo, la brecha tecnológica puede ser una limitante para favorecer un uso fácil y sencillo. Dentro de las estrategias se deberían considerar intervenciones que favorezcan la interacción social para promover la motivación interpersonal, en especial en las personas que prefieren modalidades grupales de ejercicio. (AU)
Objective: Describe the usability, actionability and understanding of videos to promote exercise at home online during the COVID-19 pandemic, analyzing the characteristics of the population, their satisfaction, adherence and barriers to physical exercise.Material and methods: A descriptive, non-experimental and cross-sectional observational design study, with a quantitative approach. Home-based videos of physical exercise and education about pain were created for people over 60 years old and distributed in the Metropolitan Region (Chile) during the months of October to December 2020. Participants had to use these videos independently at home during 4 weeks. A sample who received these videos were then voluntarily surveyed.Results: Thirty-four participants rated the videos as understandable and actionable. Usability was lower in people who perceived a lower level of technological management. Average adherence was 2 days a week for 2.5 weeks. The main perceived barrier was the lack of will, which showed a greater tendency in people who performed physical exercise in a group way before the restrictions due to the COVID-19 pandemic.Conclusions: The videos were well evaluated by the elderly population, however the technological gap can be a limitation to favor an easy and simple use. Among the strategies, interventions that favor social interaction should be considered to promote interpersonal motivation, especially in people who prefer group modalities of exercise. (AU)
Subject(s)
Humans , Middle Aged , Aged , Aged, 80 and over , Exercise , Audiovisual Aids , Coronavirus Infections , Epidemiology , Pandemics , Cross-Sectional Studies , Epidemiology, Descriptive , ChileABSTRACT
Background: Excessive blood loss is a relevant complication of partial liver resection. Topical hemostatic agents have proven useful to improve the control of the bleeding in this among other surgical indications. Until now all of these products have been based on the action of thrombin. In contrast TT-173 is a new topical hemostatic agent based on recombinant tissue factor naturally incorporated into membrane vesicles. This work sought to assess the efficacy and toxicity of TT-173 in an animal model of liver resection.Materials and Methods: Procoagulant activity of 0.15, 0.41, and 1 mg of TT-173 was evaluated in pigs subjected the resection of hepatic lobe margins. The most effective of these doses was also compared against thrombin. In addition, the toxicity, local tolerance, systemic absorption, and immunogenicity of the product were investigated in rats subjected to liver biopsy lesion.Results: The three doses of TT-173 evaluated significantly reduced the bleeding time in liver lesions. The highest dose of product was significantly more effective than the others and thrombin. Application of high doses of TT-173 in rats did not cause any local or systemic alterations. Absorption into blood stream was negligible and no immunogenic reaction against the product was detected.Conclusions: TT-173 shows favorable pharmacodynamic properties for improving hemostasis in partial liver resection which support further investigation of the product in this surgical indication.
Subject(s)
Blood Loss, Surgical/prevention & control , Hemostasis, Surgical/methods , Hemostatics/administration & dosage , Liver/injuries , Thromboplastin/administration & dosage , Administration, Topical , Animals , Disease Models, Animal , Female , Hepatectomy/adverse effects , Humans , Liver/blood supply , Liver/surgery , Male , Rats , Recombinant Proteins , SwineABSTRACT
BACKGROUND: Total knee arthroplasty is associated with blood loss during the intervention and may require allogenic blood transfusion. Treatments such as tranexamic acid and fibrin sealants improved the bleeding control in several clinical trials, but the hemorrhage associated with the intervention is still significant. Thus far, very few studies have evaluated hemostatic treatments in animal models of total knee arthroplasty. This work describes a sheep model of bleeding associated with total knee arthroplasty and investigates a new class of hemostatic treatment based on recombinant tissue factor. METHODS: Sheep were treated with the anticoagulant heparin, and the joint was accessed by a paramedial incision. Ligaments and menisci were eliminated and femoral condyles and tibia plateau were sectioned exposing the trabecular bone. An intra-articular drain was used to recover and quantify the blood loss during the 90-min period after treatment. The efficacy of one milligram and three milligrams of TT-173 was evaluated and compared with tranexamic acid. The occurrence of analytical alterations and systemic absorption was also investigated. RESULTS: Treatment with TT-173 reduced the blood loss in comparison with control or tranexamic acid. No significant differences were observed between the two doses evaluated. Moreover, a dose of six milligrams of TT-173 did not induce any clinical or analytical alteration, and significant systemic absorption was not observed. CONCLUSION: Data obtained strongly suggest that TT-173 could be useful in reducing the blood loss associated with total knee arthroplasty and without safety concerns derived from the systemic absorption of the product.
