Radiological differential diagnosis and management of retroperitoneal hematomas posterior to radical inguinal orchiectomies. A case report.

Introduction: Retroperitoneal hematomas are rare complications of radical inguinal orchiectomy. This case report discusses their radiological differential diagnosis and management. Case presentation: A radical inguinal orchiectomy was performed on a 27-year-old patient. After discharge, he referred back pain. Computed tomography showed a retroperitoneal hematoma. A conservative approach was decided. Discussion: Traditionally, retroperitoneal hematomas have been considered possible radiologic pitfalls, which has therapeutical implications. This pitfall seems less likely in contemporary clinical practice.A conservative approach is preferred in stable patients, whereas active management should be offered to unstable patients. Conclusion: Future studies are necessary to offer evidence-based therapeutical options.

Trends in treatments for erectile dysfunction in Chile between 2010 and 2020 with special focus on penile prostheses.

OBJECTIVES: Evidence regarding demand trends for erectile dysfunction (ED) treatments are scarce in South America. This study aims to evaluate trends in ED treatments in Chile over a 10-year period (2010- 2020) and estimate the potential number of candidates for penile prosthesis. MATERIALS AND METHODS: Sales trends of pharmacological treatments and penile prosthesis were obtained from market studies. The potential number of candidates for penile prosthesis implantation was calculated by crossing epidemiological data with previously reported ED prevalence, proportion of sexually active men, percentage of men seeking medical assistance for ED, and the proportion of patients who are non-responders to ED oral drug therapies Results: In the 10-year studied period, the Chilean male population older than 50 years increased 34.7%, with an average annual variation (AAV) of 3.4%. For the same period, the sales of oral drug therapies for ED increased by 71.3% (AAV 6.2%), the sales of intracavernosal vasoactive agents (ICVA) decreased by 0.4% (AAV -0.2%), and penile prosthesis sales increased by 113% (AAV 6.7%). We estimated that only 0.05% of sexually active men older than 50 years old with ED who sought medical assistance finally had a penile prosthesis implanted to manage their condition. CONCLUSIONS: Demand for ED oral drug therapies significantly increased in Chile during the last decade, while ICVA remained stable. The annual rate of penile prosthesis implantation increased. However, the gap between the potential penile prosthesis candidates and the actual number of devices implanted is suspected to remain extremely high.

Co-morbilidad neuro-psiquiátrica en infección por VIH / Neuropsychiatric comorbidity in HIV infection

Resumen Introducción: Aproximadamente 50% de las personas con infección por VIH padecen de alguna patología neuro-psiquiátrica. Características intrínsecas del virus, sus complicaciones, tratamiento y el contexto socio-cultural de los infectados facilitan el desarrollo de estas co-morbilidades, que determinan, en parte, el curso y pronóstico de las personas con infección por VIH. Objetivo: Introducir en la fisiopatología, características clínicas y manejo de la patología neuro-psiquiática en la infección por VIH, centrándose en dos de sus cuadros de mayor prevalencia: el trastorno neuro-cognitivo asociado al VIH (HAND) y el trastorno depresivo mayor (TDM). Desarrollo: En general, la detección y el tratamiento precoz de la patología neuropsiquiátrica en personas con infección por VIH mejora la calidad de vida de los pacientes, el curso clínico de la infección y mejora la adherencia al tratamiento anti-retroviral, lo que constituye una herramienta importante en el control de la propagación del VIH.

Abstract Background: The prevalence of neuropsychiatric disorders in HIV infected individuals is around 50%. Despite this, these diseases are often underdiagnosed and undertreated. Direct effects of the virus, opportunistic infections, adverse effects of antiretroviral therapy and the sociocultural context of the infected persons, contribute to the development of HIV associated neurocognitive disorder (HAND) and major depressive disorder (MDD), both of which have an impact in quality of life and disease progression. Aim: To introduce physicians in the pathophysiology, clinical features and management of psychiatric disease in seropositive patients. Content: Early detection and treatment of neuropsychiatric comorbidity in HIV infected individuals improve clinical outcomes, quality of life and is an important milestone in the control of the pandemic.

Analysis of Biomaterials as Green Coagulants to Control Suspended Solids for Surface Water Treatment.

This study explores the use of natural, ecological coagulant-flocculants to reduce suspended particles in water. Three compounds were tested, namely: diatomaceous earth, calcium lactate and lactic acid. For this purpose, experiments in jar tests were carried out and the best compound was submitted to an optimization in order to evaluate the most significant parameters affecting its use as coagulant-flocculant. First results evidenced that lactic acid remove 71% of the suspended particles during the first five minutes, and up to 83% during the first 15 min. To optimize its use, the range of suspended particles concentration, lactic acid dose and salinity gradient was tested by means of an incomplete 33 factorial design. This technique allows reducing the number of experiments to be carried out through a response surface methodology, which enables to infer the values of the dependent variables in not studied situations, by means of predictive equations. As a result of the experiments carried out, optimal conditions to remove suspended particles were set at a lactic acid concentration of 1.75 g·L-1. As lactic acid may be obtained biotechnologically from organic wastes, this use supposes a promising area by keeping products and materials in use and contributing to a circular economy.

[Neuropsychiatric comorbidity in HIV infection]. / Co-morbilidad neuro-psiquiátrica en infección por VIH.

BACKGROUND: The prevalence of neuropsychiatric disorders in HIV infected individuals is around 50%. Despite this, these diseases are often underdiagnosed and undertreated. Direct effects of the virus, opportunistic infections, adverse effects of antiretroviral therapy and the sociocultural context of the infected persons, contribute to the development of HIV associated neurocognitive disorder (HAND) and major depressive disorder (MDD), both of which have an impact in quality of life and disease progression. AIM: To introduce physicians in the pathophysiology, clinical features and management of psychiatric disease in seropositive patients. CONTENT: Early detection and treatment of neuropsychiatric comorbidity in HIV infected individuals improve clinical outcomes, quality of life and is an important milestone in the control of the pandemic.

Benefits of phytoremediation amended with DC electric field. Application to soils contaminated with heavy metals.

The objective of this study was to determine the influence of the DC electric current in the physicochemical properties of soil. The electric current may induce changes in pH and electric conductivity that will be reflected in the distribution of the electric potential in the soil specimen. This information will be used for the development of a phytoremediation technology amended with electric current. The results showed that low or moderate voltage gradients (0.67 V/cm) induced small changes in physicochemical properties of soil that do not compromise plant survival. The selected voltage gradient was used in electro-phytoremediation tests in soil contaminated with heavy metals (Cd, Co, Cr, Cu, Pb and Zn). Two plants species adapted to the soil and climate conditions were selected (Brassica rapa L. subsp. rapa and Lolium perenne L.). The electric field enhanced the plant growing, mainly in L. perenne, and increased the phytoremediation of the 6 metals. Mixed cultures of the two plant species showed interesting results for large scale applications.