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1.
Radiol Med ; 114(3): 425-36, 2009 Apr.
Article in English, Italian | MEDLINE | ID: mdl-19277838

ABSTRACT

PURPOSE: The authors sought to evaluate indications, technical feasibility and clinical efficacy of computed tomography (CT)-guided pudendal nerve infiltration in patients with chronic anoperineal pain by reviewing the role of the CT technique in their personal experience and in the recent interventional literature. MATERIALS AND METHODS: Twenty-eight women, mean age 50 years, and with a diagnosis of pudendal neuralgia on the basis of clinical and electromyographic criteria were enrolled in the study. CT-guided pudendal nerve injections were performed during three consecutive sessions held 2 weeks apart. In each session, patients received two percutaneous injections: one in the ischial spine, and the other in the pudendal (Alcock's) canal. RESULTS: One patient dropped out of the study after the first session. At clinical assessment, 24h h after treatment, 21/27 patients reported significant pain relief. At follow-up at 3, 6, 9 and 12 months, 24/27 patients reported a>or=20% improvement in the Quality of Life (QOL) index. CONCLUSIONS: In pudendal nerve entrapment, CT-guided perineural injection in the anatomical sites of nerve impingement is a safe and reproducible treatment with a clinical efficacy of 92% at 12 months.


Subject(s)
Neuralgia/diagnostic imaging , Neuralgia/drug therapy , Radiography, Interventional/methods , Tomography, X-Ray Computed/methods , Acetaminophen/administration & dosage , Adult , Aged , Anti-Inflammatory Agents/administration & dosage , Anticonvulsants/administration & dosage , Antidepressive Agents/administration & dosage , Female , Humans , Ibuprofen/administration & dosage , Injections/methods , Middle Aged , Nerve Compression Syndromes/diagnostic imaging , Nerve Compression Syndromes/drug therapy , Treatment Outcome
2.
J Chemother ; 16 Suppl 5: 30-3, 2004 Nov.
Article in English | MEDLINE | ID: mdl-15675473

ABSTRACT

The purpose of this retrospective study was to assess the effectiveness and safety of Percutaneous Vertebroplasty and Kyphoplasty, in the treatment of pain deriving from neoplastic vertebral compression fractures (VCF). We treated 33 oncologic patients with these new techniques (2 pts with aggressive haemangiomas, 8 pts with myelomas and 23 pts with metastases) suffering from severe motion pain in the back, notwithstanding conservative treatment with medication and corset therapy, in the absence of neurological signs. In 3 selected patients we associated radiofrequency heat ablation with vertebroplasty in the treatment of metastases. The aim is to destroy tumor tissue and to thrombose the paravertebral and intravertebral venous plexus before stabilizing the vertebra.


Subject(s)
Spinal Fractures/surgery , Spinal Neoplasms/complications , Spine/surgery , Aged , Aged, 80 and over , Catheter Ablation , Humans , Middle Aged , Spinal Fractures/etiology
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