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1.
Phys Med Biol ; 50(20): 4811-22, 2005 Oct 21.
Article in English | MEDLINE | ID: mdl-16204874

ABSTRACT

We have considered the theoretical background of biological tissue complex polarization analysis: (1) polarization mapping; (2) polarization-correlation mapping; (3) polarization correlometry. The technique of interferometric measurements of 2D distributions of the complex degree of mutual polarization of biological tissue images has been proposed. The totality of diagnostically urgent interconnections between the statistical and correlation structure of biological tissue polarization images and the optical-geometrical structure of their architectonics has been determined.


Subject(s)
Image Interpretation, Computer-Assisted/methods , Microscopy, Polarization/methods , Models, Biological , Neoplasms/pathology , Refractometry/methods , Tomography, Optical Coherence/methods , Animals , Computer Simulation , Humans , Neoplasms/physiopathology , Statistics as Topic , Structure-Activity Relationship
2.
J Biomed Opt ; 10(6): 064025, 2005.
Article in English | MEDLINE | ID: mdl-16409090

ABSTRACT

We investigate the statistical polarization parameters of biological tissue histological section images with different morphological structure. First we outline the results of polarization coordinate mapping and analysis of the statistics of the first to fourth orders of biological tissue image polarization azimuth and ellipticities. Second, we study the statistics of the first to fourth orders of coordinate distributions of the complex degree of mutual polarization (CDMP) of biological tissue images. Finally, we consider the diagnostic possibilities of investigating 2-D distributions of CDMP of images that correspond to physiologically normal and degeneratively and/or dystrophycally changed biological tissues that are being analyzed.


Subject(s)
Connective Tissue/ultrastructure , Image Enhancement/methods , Image Interpretation, Computer-Assisted/methods , Microscopy, Polarization/methods , Refractometry/methods , Tomography, Optical Coherence/methods , Animals , Computer Simulation , Humans , Light , Models, Biological , Scattering, Radiation
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