ABSTRACT
The problem of antibiotic-associated conditions is one of the most actual problems of clinical practice. The antibiotic-associated diarrhea is a multidisciplinary problem. Investigations of the small intestine microecological status and assessment of microflora at the patients receiving antibiotics testifies to dysbiosis existence. In article results of open-label investigation of a multispecies probiotic RioFlora Balance using for antibiotic-associated diarrhea prophylaxis in patients used antibacterial therapy are presented.
Subject(s)
Anti-Bacterial Agents/adverse effects , Colon/microbiology , Diarrhea/microbiology , Diarrhea/prevention & control , Probiotics/therapeutic use , Adult , Anti-Bacterial Agents/administration & dosage , Anti-Bacterial Agents/therapeutic use , Bronchopneumonia/drug therapy , Colon/drug effects , Diarrhea/chemically induced , Feces/microbiology , Female , Humans , Male , Probiotics/administration & dosage , Treatment OutcomeSubject(s)
Anti-Inflammatory Agents, Non-Steroidal/adverse effects , Gastrointestinal Diseases/prevention & control , Proton Pump Inhibitors/therapeutic use , Anti-Inflammatory Agents, Non-Steroidal/administration & dosage , Anti-Inflammatory Agents, Non-Steroidal/therapeutic use , Choice Behavior , Diabetes Mellitus/drug therapy , Drug Interactions , Gastrointestinal Diseases/chemically induced , Gastrointestinal Diseases/metabolism , Humans , Hypertension/complications , Hypertension/drug therapy , Myocardial Ischemia/complications , Myocardial Ischemia/drug therapy , Obesity/complications , Obesity/drug therapy , Osteochondrosis/complications , Osteochondrosis/drug therapy , Practice Patterns, Physicians' , Proton Pump Inhibitors/administration & dosage , Proton Pump Inhibitors/adverse effectsABSTRACT
In this article result of medication methocinium iodide (Methacin) using at patients with irritable bowel syndrome are observed.
Subject(s)
Irritable Bowel Syndrome/drug therapy , Muscarinic Antagonists/administration & dosage , Oxyphenonium/administration & dosage , Adult , Female , Humans , Male , Middle Aged , Retrospective StudiesABSTRACT
The discussion concerns onset and pathogenesis of functional intestinal diseases. Current data are presented on association of functional intestinal diseases with different infectious agents with illustration on the model of postinfectious irritable colon syndrome (ICS). ICS-like conditions in patients who had previously intestinal infections are considered.
Subject(s)
Bacteria/isolation & purification , Intestinal Mucosa/microbiology , Irritable Bowel Syndrome/microbiology , Humans , Risk FactorsABSTRACT
The aim of the clinical research was to study the efficacy of Saccharomyces boulardii in treatment of patients with Inflammatory Bowel Diseases. Results of investigation demonstrate more rapid regression of intestinal dyspepsia symptoms, decreasing clinical activity of IBD and improvement of intestinal microbiota composition in IBD patients have been treated by Saccharomyces boulardii. Lyophilized Saccharomyces boulardii are compatible with medical agents of the standard IBD therapy and have high level of safety.
Subject(s)
Inflammatory Bowel Diseases/microbiology , Inflammatory Bowel Diseases/therapy , Saccharomyces , Female , Humans , Intestines/microbiology , MaleABSTRACT
Irritable bowel syndrome is one of the most frequent diseases of the digestive system. Psychodiagnostic investigation of patients with IBS testifies to presence of asthenic frustration. In article results of preparation Ladasten use are presented in therapy of patients with irritable bowel syndrome.
Subject(s)
Adamantane/analogs & derivatives , Anxiety/drug therapy , Asthenia/drug therapy , Irritable Bowel Syndrome/drug therapy , Adamantane/administration & dosage , Adamantane/therapeutic use , Anxiety/psychology , Asthenia/psychology , Drug Therapy, Combination , Female , Gastrointestinal Agents/administration & dosage , Gastrointestinal Agents/therapeutic use , Humans , Irritable Bowel Syndrome/psychology , Male , Neuropsychological Tests , Surveys and Questionnaires , Treatment OutcomeABSTRACT
According to the 1996 WHO Report, the world is heading for a major crisis in public health as outbreaks of new and re-emerging infectious diseases are striking at increasing frequencies within the past 10 to 15 years. The given information is true not only for an infection. On the other side eventually a food of the persons considerably changes. The urgent question which needs to be addressed is the nutrition modification and optimization for public health improvement.
Subject(s)
Food Supply , Food , Nutrition Assessment , Female , Humans , MaleABSTRACT
AIM: To study efficacy of a combination of proton pump inhibitor (PPI) and bismuth tripotassium dicitrate (BTD) in gastric ulcers (GU) induced by non-steroid anti-inflammatory drugs (NSAD) in rheumatic patients with factors affecting PPI efficacy. MATERIAL AND METHODS: Fifty rheumatic patients entered the study (5 males and 45 females, mean age 63.5 +/- 6.2 years) with NSAD-induced GU. Criteria of participation in the study: ulcer size > 1.0 cm, 2 and more ulcers, administration of glucocorticoids (GC) and/or cytotoxic drugs. The patients were divided into two groups. Group 1 patients received omeprasol 20 mg twice a day + BTD 240 mg twice a day; group 2 patients received omeprasol alone 20 mg twice a day. The groups were matched by demographic and clinical parameters, consisted mainly of women with rheumatoid arthritis, most of the patients took GC, methotrexate or leflunamid. The result of the treatment was evaluated by the findings of endoscopic examination 4 and 8 weeks after treatment. RESULTS: Three patients from group 1 and 2 patients from group 2 were withdrawn from the study. For 4 weeks ulcer heeling was achieved in 15 patients of group 1 (68.2%) and 8 patients of group 2 (34.8%), p = 0.038. On week 8 ulcers healed in 86.3 and 78.3% patients, respectively. Severe side effects were absent. CONCLUSION: Combination of omeprasol with BTD stimulated heeling of NSAD-induced gastric ulcer.
Subject(s)
Anti-Inflammatory Agents, Non-Steroidal/adverse effects , Anti-Ulcer Agents/therapeutic use , Omeprazole/therapeutic use , Organometallic Compounds/therapeutic use , Proton Pump Inhibitors/therapeutic use , Stomach Ulcer/drug therapy , Aged , Anti-Inflammatory Agents, Non-Steroidal/therapeutic use , Drug Therapy, Combination , Female , Humans , Male , Middle Aged , Stomach Ulcer/chemically induced , Treatment OutcomeABSTRACT
The authors consider mechanism of biliary dysfunction in cholelithiasis responsible for the development of secondary changes in parenchyma and pancreatic ductal system and effect of cholecystectomy on bile lithogenecity in patients with chronic biliary pancreatitis. A high-precision technique for instrumental diagnosis (endosonography) yielded data on the role of microliths and biliary sludge in pathogenesis of chronic biliary pancreatitis. The necessity to use ursodeoxycholic acid derivatives for the treatment of this pathology is substantiated.
Subject(s)
Bile/metabolism , Cholecystectomy/adverse effects , Cholelithiasis/surgery , Pancreas/pathology , Pancreatitis, Chronic/etiology , Adult , Aged , Cholagogues and Choleretics/therapeutic use , Cholangiopancreatography, Endoscopic Retrograde , Cholelithiasis/diagnosis , Endosonography , Female , Follow-Up Studies , Humans , Male , Middle Aged , Pancreas/diagnostic imaging , Pancreatitis, Chronic/diagnosis , Pancreatitis, Chronic/drug therapy , Prognosis , Ursodeoxycholic Acid/therapeutic useABSTRACT
The article contains information about severe side effects of long-term acid suppression with non-select proton pump inhibitors (PPI) treatment of gastroesophageal reflux disease (GERD). As far as concern patients with heartborn without esophagitis (non-erosive GERD) using PPI doesn't correspond the pathogenesis and hardly has any advantages. Therapy with gastric acidity inhibitors increases risk of acute gastroenteritis and community-acquired pneumonia. Quality of life is rising and symptoms of gastro-esophageal reflux are getting away thanks to topical harmless treatment GERD without severe esophagitis Pepsan-R.
Subject(s)
Gastroesophageal Reflux/drug therapy , Gastrointestinal Agents/therapeutic use , Histamine H2 Antagonists/therapeutic use , Proton Pump Inhibitors/adverse effects , Dose-Response Relationship, Drug , Femoral Neck Fractures/epidemiology , Femoral Neck Fractures/etiology , Gastric Acid/metabolism , Gastroesophageal Reflux/etiology , Gastroesophageal Reflux/metabolism , Gastrointestinal Agents/administration & dosage , Gastrointestinal Agents/adverse effects , Histamine H2 Antagonists/administration & dosage , Histamine H2 Antagonists/adverse effects , Humans , Pneumonia/epidemiology , Pneumonia/etiology , Proton Pump Inhibitors/administration & dosage , Proton Pump Inhibitors/therapeutic use , Quality of Life , Time FactorsABSTRACT
In this article the comparative analysis of various methods of Helicobacter pylori verification is shown. Also algorithm of optimization of helicobacteriosis diagnostic, developed on the basis of a comparative estimation of results of various diagnostic techniques is presented. According to this algorithm, for increase of accuracy of helicobacteriosis diagnostic it is recommended to use at least two, and it is better three diagnostic methods: the combination of fast urease test or Helic-test with a histologic method (biopsy material from a stomach corpus) or polymerase chain reaction (ureC gene detection) is preferable. For an efficiency estimation of eradication therapy we recommend "Helic-test" as an effective noninvasive method that is especially important for children.
Subject(s)
Digestive System Diseases/microbiology , Helicobacter Infections/microbiology , Helicobacter pylori/genetics , Helicobacter pylori/pathogenicity , Virulence Factors/genetics , Digestive System Diseases/drug therapy , Drug Resistance, Bacterial/genetics , Genes, Bacterial , Helicobacter Infections/drug therapy , Helicobacter pylori/drug effects , Humans , VirulenceSubject(s)
Anti-Bacterial Agents/administration & dosage , Clarithromycin/administration & dosage , Drug Resistance, Bacterial , Helicobacter Infections , Helicobacter pylori , Stomach Ulcer , Female , Helicobacter Infections/drug therapy , Helicobacter Infections/epidemiology , Humans , Male , Russia/epidemiology , Stomach Ulcer/drug therapy , Stomach Ulcer/epidemiology , Stomach Ulcer/microbiology , Urban PopulationABSTRACT
It is known, that anxiety is one of the most wide-spread mental disorders in-between psychiatric state and it takes part in pathogenesis a lot of somatic diseases as well. At the same time the host bowel microbiota participates in metabolic control of vital human functions such as mood and behavioural reactions. This title connection reveals some new therapeutic opportunity in treatment of psychiatric disorders that based on using with probiotics. In case non-clinically significant anxiety it is claimed to use probiotic (Enterol) however in case clinically significant anxiety it is claimed to use non-benzodiazepine tranquilizer (Stresam).
Subject(s)
Anti-Anxiety Agents/therapeutic use , Anxiety Disorders , Intestinal Diseases , Oxazines/therapeutic use , Probiotics/therapeutic use , Anxiety Disorders/complications , Anxiety Disorders/drug therapy , Anxiety Disorders/pathology , Anxiety Disorders/physiopathology , Behavior/drug effects , Humans , Intestinal Diseases/complications , Intestinal Diseases/diet therapy , Intestinal Diseases/pathology , Intestinal Diseases/physiopathologyABSTRACT
In the article the questions of eating attitudes of people in advanced age are considered. Inspection of 54 people of St. Petersburg in the age from 65 to 84 included questioning (biological, social and questions of eating contents), estimation of eating attitude (the eating attitude test EAT-26, the Dutch eating behaviour questionnaire) and psychological testing (techniques of an estimation of complaints, attitudes, levels of anxiousness, depression, astenia, aggression and quality of life). Symptoms of eating disorders with restrictive and emotional tendencies were registered in 14,8% of people of advanced age. Communications of eating attitude with social factors, eating preferences, application of a diet, a degree of a dissatisfaction of body weight, arterial blood pressure and psychological parameters have been revealed.
