ABSTRACT
AIMS: To compare adverse events and health-related quality of life in ambulatory home-based chemotherapy with those in inpatient. DESIGN: Prospective non-randomized observational study. METHODS: Participants were divided into two groups according to patients' preference receiving chemotherapy. RESULTS: Sixty-four participants were enrolled in the inpatient, and 111 were in an ambulatory home-based chemotherapy. The frequency of anaemia, neutropenia and thrombocytopenia was significantly higher in inpatient group than in ambulatory home-based chemotherapy group (p < .001, <.001 and .002, respectively). Nausea, mucositis, and fatigue were more common in ambulatory home-based chemotherapy group than in inpatient group (p < .001, .022, and .005, respectively). Patients in the ambulatory home-based chemotherapy group showed higher social well-being (SWB) scores than inpatient group (coefficient 1.92, 95% confidence interval [CI] 0.65 to 3.19, p .003).
