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Article in English | MEDLINE | ID: mdl-19963517

ABSTRACT

A number of revolutionary techniques have been developed for cardiac electrophysiology research to better study the various arrhythmia mechanisms that can enhance ablating strategies for cardiac arrhythmias. Once the three-dimensional high resolution cardiac optical imaging data is acquired, it is time consuming to manually go through them and try to identify the patterns associated with various arrhythmia symptoms. In this paper, we present an interactive computer wizard that helps cardiac electrophysiology researchers to visualize and analyze the high resolution cardiac optical imaging data. The wizard provides a file interface that accommodates different file formats. A series of analysis algorithms output waveforms, activation and action potential maps after spatial and temporal filtering, velocity field and heterogeneity measure. The interactive GUI allows the researcher to identify the region of interest in both the spatial and temporal domain, thus enabling them to study different heart chamber at their choice.


Subject(s)
Arrhythmias, Cardiac/physiopathology , Cardiac Electrophysiology/methods , Computer Simulation , Heart/physiopathology , Action Potentials/physiology , Algorithms , Animals , Arrhythmias, Cardiac/diagnosis , Arrhythmias, Cardiac/epidemiology , Computers , Death, Sudden, Cardiac/epidemiology , Electrocardiography , Epicardial Mapping/methods , Equipment Design , Heart/physiology , Humans , Imaging, Three-Dimensional/methods , Models, Animal , Models, Cardiovascular , Software , Swine , United States/epidemiology , User-Computer Interface
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