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1.
Medicine (Baltimore) ; 102(13): e33452, 2023 Mar 31.
Article in English | MEDLINE | ID: mdl-37000049

ABSTRACT

Posterior tibial slope (PTS) is important for the success of high tibial osteotomy and unicondylar knee arthroplasty applications, as it provides anterior cruciate ligament function. In the literature, different studies have been carried out with various imaging methods to measure PTS in populations of different ethnic origins. In this study, it was aimed to detect PTS in the medial (MPTS) and lateral (LPTS) tibial condyles with computed tomography in a Turkish population sample and to compare the results between age groups (<65, ≥ 65), genders, sides, and literature data. In our sample, 39 left and 33 right knee images of 37 men and 35 women with a mean age of 52.01 ±â€…21.27 were evaluated. The tibial proximal anatomical axis was determined by the midpoint method. The MPTS and LPTS was evaluated by two different observers according to this axis. Thereby the global PTS (GPTS) was calculated as an arithmetic mean of MPTS and LPTS values. Measurements were repeated 2 weeks after the first measurement and values were analyzed. A significant difference was found between the mean of MPTS, LPTS, and GPTS in the whole population (P = .002), in men (P = .02) and in women (P = .02). On the other hand, there was no significant difference compared according to age, gender, and side by mean of same parameters. In comparison of the results of our Turkish population sample with other studies in the literature, MPTS and LPTS were similar to Chinese (P = .22, P = .07) and Japanese (P = .96, P = .67) populations, while different to White Asian (P < .001, P < .001) and Korean (P < .001, P < .001) populations. The midpoint method is a safe measurement method in computed tomography-based studies for the evaluation of PTS. Implant designs produces for different populations may not be suitable for the Turkish population. More comprehensive and detailed studies are needed to represent the Turkish population.


Subject(s)
Anterior Cruciate Ligament Injuries , Arthroplasty, Replacement, Knee , Humans , Male , Female , Adult , Middle Aged , Aged , Knee Joint/surgery , Tibia/diagnostic imaging , Tibia/surgery , Anterior Cruciate Ligament/diagnostic imaging , Anterior Cruciate Ligament/surgery , Retrospective Studies , Tomography, X-Ray Computed , Anterior Cruciate Ligament Injuries/surgery
2.
Turk J Surg ; 38(3): 302-305, 2022 Sep.
Article in English | MEDLINE | ID: mdl-36846065

ABSTRACT

Splanchnic artery aneurysms are rare vascular lesions with a high risk of rupture regardless of their size. Symptoms may vary from simple abdominal pain or vomiting to morbid conditions like haemorrhagic shock; however, most aneurysms are asymptomatic and difficult to diagnose. In this study, it was aimed to present the case of a 56-year-old female with a ruptured pancreaticoduodenal artery aneurysm treated by coil embolization.

3.
J Vasc Interv Radiol ; 33(1): 62-70.e1, 2022 01.
Article in English | MEDLINE | ID: mdl-34600128

ABSTRACT

PURPOSE: To evaluate the safety, effectiveness, and outcomes of endovascular recanalization of chronic total occlusion (CTO) of the superficial femoral artery (SFA) in patients with critical limb ischemia (CLI) after failed surgical bypass graft. METHODS: Endovascular recanalization of SFA CTO was performed for 26 consecutive CLI patients with failed bypass grafts from 2016 to 2020. Patient demographics, bypass and lesion characteristics, procedural data, technical, and clinical outcomes were evaluated. RESULTS: The technical success rate was 96.2% (25/26). Retrograde arterial access was used in 16 (61.6%) patients. Additional tibial and iliac angioplasty was performed in 15 and 2 patients, respectively. Fifteen complications occurred in 10 patients, including thrombosis, embolism, vessel rupture, dissection, arteriovenous fistula, and pseudoaneurysm. Pain relief and wound healing were achieved in 22 patients. The primary, assisted primary, and secondary patency rates were 95.5%, 100%, and 100% at 6 months, 81.8%, 95.5%, and 100% at 12 months, and 76.7%, 82.7%, and 87.5% at 24 months, respectively. By univariate analysis, hyperlipidemia (hazard ratio = 7.82; 95% CI: 1.27-48.04, P = .026) was found to be the only significant risk factor related to primary patency loss. Amputation-free survival and limb salvage rates were 100% and 100% at 6 months, 100% and 100% at 12 months, and 87.1% and 93.8% at 24 months, respectively. CONCLUSIONS: Endovascular recanalization of SFA CTO in CLI patients with graft failures is effective with high technical success rates. Acceptable limb salvage and amputation-free survival rates make this technique a reasonable alternative to repeat surgery for high-risk patients.


Subject(s)
Ischemia , Peripheral Arterial Disease , Femoral Artery/diagnostic imaging , Femoral Artery/surgery , Humans , Ischemia/diagnostic imaging , Ischemia/etiology , Ischemia/surgery , Limb Salvage , Peripheral Arterial Disease/diagnostic imaging , Peripheral Arterial Disease/surgery , Retrospective Studies , Risk Factors , Treatment Outcome , Vascular Patency
4.
Vascular ; 30(5): 1008-1012, 2022 Oct.
Article in English | MEDLINE | ID: mdl-34406103

ABSTRACT

OBJECTIVES: Chronic total occlusion (CTO) of the EVAR graft is a rare and serious complication. Traditionally, surgical intervention with prosthetic graft replacement or bypass graft implantation is performed. However, there are limited data in endovascular era. METHODS: We present a case of a 68-year-old male with a history of late EVAR graft occlusion treated with multiple surgical interventions (femorofemoral crossover, extra-anatomic bypass surgery, and thrombectomy) five years ago. Color Doppler ultrasound (CDUS) and computed tomography (CT) angiography revealed thrombosis of the entire bypass graft. Endovascular recanalization and remodeling of the abdominal stent graft CTO was performed with a combination of bare stents and stent grafts. Rupture of the stent graft occurred on the right limb. A second covered stent was placed. RESULTS: At 12-month follow-up, the patient was symptom free. Color Doppler ultrasound surveillance showed patent aortic stent graft and downstream arteries. CONCLUSIONS: Endovascular recanalization of aortic stent graft CTO is a viable option in patients with failed bypass graft.


Subject(s)
Aortic Aneurysm, Abdominal , Blood Vessel Prosthesis Implantation , Endovascular Procedures , Aged , Aorta, Abdominal/diagnostic imaging , Aorta, Abdominal/surgery , Aortic Aneurysm, Abdominal/complications , Aortic Aneurysm, Abdominal/diagnostic imaging , Aortic Aneurysm, Abdominal/surgery , Blood Vessel Prosthesis , Blood Vessel Prosthesis Implantation/adverse effects , Blood Vessel Prosthesis Implantation/methods , Endovascular Procedures/adverse effects , Humans , Male , Prosthesis Design , Stents , Treatment Outcome
5.
Curr Med Imaging ; 18(1): 38-44, 2022.
Article in English | MEDLINE | ID: mdl-34165410

ABSTRACT

OBJECTIVE: This study aimed to investigate the feasibility of low-dose chest CT acquisition protocol for the imaging of COVID 19 disease or suspects of this disease in adults. METHODS: In this retrospective case-control study, the study group consisted of 141 patients who were imaged with low dose chest CT acquisition protocol. The control group consisted of 92 patients who were imaged with standard protocol. Anteroposterior and lateral diameters of chest, effective diameter and scan length, qualitative and quantitative noise levels, volumetric CT dose index (CTDIvol), dose length product (DLP), and size-specific dose estimations were compared between groups. RESULTS: Radiation dose reduction by nearly 90% (CTDIvol and DLP values 1.06 mGy and 40.3 mGy.cm vs. 8.07 mGy and 330 mGy.cm, respectively; p < 0.001) was achieved with the use of low-dose acquisition chest CT protocol. Despite higher image noise with low-dose acquisition protocol, no significant effect on diagnostic confidence was encountered. Cardiac and diaphragm movement-related artifacts were similar in both groups (p=0.275). Interobserver agreement was very good in terms of diagnostic confidence assessment. CONCLUSION: For the imaging of COVID-19 pneumonia or suspects of this disease in adults, lowdose chest CT acquisition protocol provides remarkable radiation dose reduction without adversely affecting image quality and diagnostic confidence.


Subject(s)
COVID-19 , Adult , Case-Control Studies , Feasibility Studies , Humans , Radiation Dosage , Retrospective Studies , SARS-CoV-2 , Tomography, X-Ray Computed
6.
J Oral Maxillofac Surg ; 79(9): 1891.e1-1891.e4, 2021 Sep.
Article in English | MEDLINE | ID: mdl-34153259

ABSTRACT

Oil-based contrast medium agents (Iofendylate) are cleared from cerebrospinal fluid very slowly. But it may remain within the tissues of the central nervous system. These substances, which were used for purposes such as myelography, cisternography, and ventriculography approximately 70 years ago and were replaced by water-soluble agents after thirty years, can rarely be detected incidentally. In this report, by presenting the intracranial radiopacities seen in 2 patients, it is aimed to increase awareness that these myeloid residues, which are rarely seen in panoramic radiography, can be diagnosed by clinicians.


Subject(s)
Incidental Findings , Myelography , Angiography , Contrast Media , Humans , Radiography, Panoramic
7.
AJR Am J Roentgenol ; 217(2): 418-425, 2021 08.
Article in English | MEDLINE | ID: mdl-34036807

ABSTRACT

OBJECTIVE. The purpose of this study was to evaluate the safety and efficacy of transhepatic pharmacomechanical thrombectomy of symptomatic acute portomesenteric venous thrombosis. MATERIALS AND METHODS. Transhepatic pharmacomechanical thrombectomy (catheter-directed thrombolysis with mechanical thrombectomy) was performed in the treatment of nine patients with symptomatic acute noncirrhotic, nonmalignant porto-mesenteric venous thrombosis. The medical records, imaging examinations, technique of transhepatic pharmacomechanical thrombectomy, and clinical outcomes were reviewed. RESULTS. The mean follow-up period was 23.1 months (range, 8-34) months. Successful recanalization of the portomesenteric venous thrombosis, restoration of hepatopetal portal flow, clinically significant improvement in the signs and symptoms of acute mesenteric ischemia, and prevention of bowel resection were achieved in all patients. The most frequent minor complication (in three patients) was minor hemorrhage through the transhepatic access track. No procedure-related major complications occurred during hospitalization. No patient had rethrombosis or complications related to portal hypertension due to portomesenteric venous thrombosis. One patient died of massive pulmonary embolism on the 7th day after treatment. Cavernous transformation of the right portal vein occurred in one patient. CONCLUSION. Transhepatic pharmacomechanical thrombectomy is a safe and effective method of treatment of symptomatic acute portomesenteric venous thrombosis and prevention of bowel infarction.


Subject(s)
Thrombectomy/methods , Venous Thrombosis/surgery , Acute Disease , Adult , Female , Humans , Male , Mesenteric Veins/surgery , Middle Aged , Portal Vein/surgery , Retrospective Studies , Treatment Outcome
8.
Turk Neurosurg ; 31(3): 385-388, 2021.
Article in English | MEDLINE | ID: mdl-33624278

ABSTRACT

AIM: To determine the prevalence of open and closed posterior superior iliac spine (PSIS) using lower abdominal computed tomography (CT) examinations. MATERIAL AND METHODS: Eight hundred and fifty (M/F:464/386) adult patients who underwent lower abdominal CT between January 2018 and December 2018 were evaluated retrospectively. One radiologist reviewed CT images of patient pelvises to assess the presence of open and closed PSIS. RESULTS: The mean age of all patients was 52.7 ± 18 years. Of the 850 patients, 522 (61.5%) had open PSIS, while 328 (38.5%) had closed PSIS. The distribution of open and closed PSIS by gender was 57.5% and 42.5% in males and 66% and 34% in females, respectively. CONCLUSION: Overall, open PSIS is more common than closed PSIS. The closed PSIS is seen more often in males than in females. If an anteromedial sacral (S)-1 screw direction is chosen for posterior fusion with rod-screw fixation, it is essential to obtain CT images for evaluation of PSIS.


Subject(s)
Ilium/diagnostic imaging , Pelvis/diagnostic imaging , Sacrum/diagnostic imaging , Adult , Aged , Bone Screws , Female , Humans , Ilium/surgery , Male , Middle Aged , Pelvis/surgery , Retrospective Studies , Sacrum/surgery , Tomography, X-Ray Computed/methods
9.
Diagn Interv Radiol ; 27(1): 147-151, 2021 Jan.
Article in English | MEDLINE | ID: mdl-33475510

ABSTRACT

PURPOSE: We aimed to obtain typical values for head, neck, chest, and abdominal computed tomography (CT) examinations from routine patients in 2018, and to review our data with national and international diagnostic reference levels (DRLs). METHODS: Single-phase head, neck, chest, and abdominal CT scans of adults performed in 64-slice CT in 2018 were included in this study. Radiation dose parameters of CT scans were obtained from the picture archiving and communication system of our hospital. Volumetric CT dose index (CTDIvol) and dose length product (DLP) values were recorded. Effective dose (ED) and scan length was calculated. A 16 cm diameter phantom is referenced for head CT, and 32 cm diameter phantom is referenced for neck, chest, and abdominal CT. Descriptive statistics of the variables were given according to the normality testing. RESULTS: Median CTDIvol value was 53 mGy for the head, 13.1 mGy for the neck, 8.3 mGy for the chest, and 8.6 mGy for the abdomen. Median DLP value was 988 mGy.cm for the head, 299 mGy.cm for the neck, 314 mGy.cm for the chest, and 457 mGy.cm for the abdomen. Median ED value was 2.07 mSv for the head, 1.76 mSv for the neck, 4.4 mSv for the chest, and 6.8 mSv for the abdomen. Considering national DRLs, median CTDIvol values of head, chest, and abdomen were lower, whereas median DLP and ED values of head and chest were higher. For the abdomen, the median DLP and ED values were lower. CONCLUSION: Overall radiation dose parameters obtained in this study points out the need for optimization of head CT examinations in our institution.


Subject(s)
Thorax , Tomography, X-Ray Computed , Abdomen/radiation effects , Adult , Head/radiation effects , Humans , Radiation Dosage , Reference Values , Thorax/radiation effects
10.
AJR Am J Roentgenol ; 216(2): 421-427, 2021 02.
Article in English | MEDLINE | ID: mdl-33325735

ABSTRACT

OBJECTIVE. Thromboangiitis obliterans (TAO) is an occlusive inflammatory disease affecting small- and medium-sized vessels that causes decrease in life quality and eventually limb loss. The only proven treatment method is smoking cessation, but it may be insufficient for limb salvage in patients with critical limb ischemia. In this single-center retrospective study, the feasibility and efficiency of endovascular treatment in TAO were evaluated. MATERIALS AND METHODS. After approval of the local institutional review board, 41 patients who underwent endovascular treatment of TAO between January 2014 and June 2019 were evaluated retrospectively. Technical success and procedure-related complications were recorded. Decrease in Rutherford classification score, relief of pain, and wound healing were evaluated to determine clinical success. Primary patency, limb salvage rate, and amputation-free survival were also evaluated. RESULTS. A total of 45 limbs were treated during the study period. Technical success was achieved in 82.2% of procedures. Mean follow-up was 29.8 months. Clinical improvement was achieved in 35 limbs. Three patients underwent major amputation and 12 patients underwent minor amputation. Amputation-free survival and limb salvage were both 93.3% at both 1 and 2 years. Reintervention was performed in 14 patients because of occlusion and clinical relapsing of the symptoms. CONCLUSION. Endovascular treatment of TAO is feasible, has a potential to prevent limb amputation in patients with critical limb ischemia, and has acceptable technical success and limb salvage rates. Because there is no consensus in treatment of TAO, prospective comparative studies are needed to determine the effectiveness of an endovascular approach.


Subject(s)
Endovascular Procedures , Ischemia/surgery , Limb Salvage , Lower Extremity/blood supply , Thromboangiitis Obliterans/surgery , Adult , Feasibility Studies , Female , Follow-Up Studies , Humans , Ischemia/diagnostic imaging , Ischemia/etiology , Male , Middle Aged , Retrospective Studies , Thromboangiitis Obliterans/complications , Thromboangiitis Obliterans/diagnostic imaging , Treatment Outcome , Vascular Patency
11.
Diagn Interv Radiol ; 27(1): 102-108, 2021 Jan.
Article in English | MEDLINE | ID: mdl-33252335

ABSTRACT

PURPOSE: We aimed to determine the safety and effectiveness of percutaneous endobiliary radiofrequency ablation of malignant biliary obstructions with a temperature-controlled radiofrequency ablation device. METHODS: In this single center retrospective study, a total of 62 consecutive patients with malignant biliary obstruction were evaluated. Thirty patients who underwent endobiliary radiofrequency ablation with metallic stent placement were in the study group and 32 patients who underwent only metallic stenting were in the control group. Outcomes of this study were technical success, complications related to the procedure, stent patency, and overall survival. RESULTS: All procedures were technically successful in both groups. There was no procedure-related mortality in either group. Procedural complication rates were similar between the groups. Although statistically not significant, the only two major complications (hemobilia requiring endovascular treatment) were in the control group. Median primary stent patency was significantly longer in the study group than in the control group (223 days vs. 158 days; P = 0.016). Median survival rates were also longer in the study group (246 days vs. 198 days; P = 0.004). CONCLUSION: Percutaneous endobiliary radiofrequency ablation is safe and feasible with this novel radiofrequency ablation device in patients with malignant biliary obstruction. Percutaneous endobiliary radiofrequency ablation has a potential to improve both stent patency and survival.


Subject(s)
Bile Duct Neoplasms , Catheter Ablation , Cholestasis , Radiofrequency Ablation , Aged , Bile Duct Neoplasms/surgery , Constriction, Pathologic , Female , Humans , Male , Retrospective Studies , Stents , Temperature , Treatment Outcome
12.
J Vasc Interv Radiol ; 32(2): 164-172, 2021 02.
Article in English | MEDLINE | ID: mdl-33248916

ABSTRACT

PURPOSE: To evaluate the feasibility and technical outcomes of retrograde access via occluded pedal arteries in endovascular treatment of critical limb ischemia (CLI) when the conventional antegrade approach fails. MATERIALS AND METHODS: One hundred fifty-one patients with CLI (age 69 y ± 10.5; 116 men) who were not surgical candidates and were treated via retrograde pedal access between January 2016 and January 2018 were evaluated retrospectively. Seventy patients in whom retrograde access was performed through occluded arteries constituted the occluded group, and 81 patients who were treated via retrograde access from patent arteries constituted the nonoccluded group. Pedal access success, lesion crossing success, angiographic success, overall technical success, and procedure-related complications were evaluated and compared between groups. RESULTS: Pedal access success (74 of 78 vs 83 of 87 attempts; P = .873) and lesion crossing success (64 of 78 vs 77 of 87 lesions; P = .340) were comparable between subgroups. Angiographic success (54 of 78 vs 77 of 87 lesions; P = .012) and overall technical success (48 of 70 vs 72 of 81 patients; P = .004) rates were lower in the occluded group. Procedure-related complications were similar between groups (P = .096). CONCLUSIONS: Retrograde pedal access from occluded pedal arteries is a feasible option when an antegrade approach fails in endovascular treatment of CLI. Although it has lower technical success, its use enables angiosome-directed therapy and has the potential to improve the outcomes of the procedure.


Subject(s)
Angioplasty, Balloon , Ischemia/therapy , Peripheral Arterial Disease/therapy , Adult , Aged , Aged, 80 and over , Angioplasty, Balloon/adverse effects , Angioplasty, Balloon/instrumentation , Critical Illness , Drug-Eluting Stents , Feasibility Studies , Female , Humans , Ischemia/diagnostic imaging , Ischemia/physiopathology , Male , Middle Aged , Peripheral Arterial Disease/diagnostic imaging , Peripheral Arterial Disease/physiopathology , Retrospective Studies , Treatment Outcome
13.
J Stroke Cerebrovasc Dis ; 29(8): 104923, 2020 Aug.
Article in English | MEDLINE | ID: mdl-32689613

ABSTRACT

OBJECTIVE: In this prospective study, we aimed to investigate the presence and evolution of cerebellar cognitive affective syndrome in a cohort of isolated cerebellar stroke with no known cognitive or psychiatric impairment. We tried to distinguish the unconfounded effect of cerebellar lesions on neuropsychological processing. METHODS: After a meticulous exclusion procedure based on possible confounders, we recruited 14 patients and 13 age-matched healthy controls to the study, prospectively. All of the patients had a detailed initial neuropsychological assessment at the first week and a follow-up assessment at the 4th month after stroke. RESULTS: The prevalence of cognitive or behavioral-affective abnormalities in our cohort were 86% and 64% respectively. The patients exhibited mild and transient affective-behavioral abnormalities except for depressive symptoms that persisted in the subacute stage. They scored lower in general cognitive performance as revealed by mini mental test (p=0.001). Memory, executive functions, attention and working memory, central processing speed, and linguistic abilities were impaired (p<0.001; p=0.001; p=0.007; p=0.05; p<0.001 respectively). Improvement was evident only in memory domain of the cognitive functions in the subacute stage. Cognitive impairment was more likely with a medial or posterolateral infarct (p=0.014). Behavioral-affective abnormalities were not associated with a specific location in our cohort. Age seemed to negatively correlate with the recovery in general cognitive performance on the follow-up. CONCLUSIONS: These findings show that acute denervation of cerebellocortical projections leads to mild affective-behavioral abnormalities, and full-blown cerebellar cognitive affective syndrome is rare. However, cognition was significantly affected after an acute cerebellar infarct even in a previously healthy, non-demented pure population.


Subject(s)
Affect , Brain Stem Infarctions/psychology , Cerebellar Diseases/psychology , Cerebellum/blood supply , Cognition Disorders/psychology , Cognition , Mood Disorders/physiopathology , Acute Disease , Attention , Brain Stem Infarctions/diagnosis , Brain Stem Infarctions/epidemiology , Brain Stem Infarctions/physiopathology , Case-Control Studies , Cerebellar Diseases/diagnosis , Cerebellar Diseases/epidemiology , Cerebellar Diseases/physiopathology , Cognition Disorders/diagnosis , Cognition Disorders/epidemiology , Cognition Disorders/physiopathology , Executive Function , Female , Humans , Language , Male , Memory , Middle Aged , Mood Disorders/diagnosis , Mood Disorders/epidemiology , Mood Disorders/psychology , Prevalence , Prospective Studies , Risk Factors , Time Factors , Turkey/epidemiology
14.
AJR Am J Roentgenol ; 215(3): 753-759, 2020 09.
Article in English | MEDLINE | ID: mdl-32406771

ABSTRACT

OBJECTIVE. Metallic stenting of malignant biliary strictures is the preferred method of palliation, because most patients present when the condition is inoperable. Most metallic stents, however, are occluded 6-8 months after deployment. Intraductal radiofrequency ablation has been used in previous studies to improve stent patency. The purpose of this study was to assess a single-center experience with percutaneous intraductal microwave ablation of malignant biliary strictures. MATERIALS AND METHODS. In this retrospective case series study, data on 12 patients with malignant biliary obstruction who underwent percutaneous intraductal microwave ablation followed by metallic stenting were evaluated. Ablation procedures were performed with generator frequencies of 902-928 MHz, power set at 6-10 W, and ablation time of 60-90 seconds in a temperature-controlled manner with target temperature set at 80°C. RESULTS. Causes of malignant biliary obstruction were pancreatic carcinoma in four patients, gastric antrum carcinoma in three, cholangiocarcinoma in two, metastasis in two, and gallbladder carcinoma in one patient. Percutaneous intraductal microwave ablation and metallic stenting were performed successfully in all patients. There was no procedural mortality or major complication. The most common minor complication was abdominal pain. Biliary decompression was achieved in all patients at the end of the first month. The mean follow-up time was 9.4 months. The median primary stent patency period was 231 days. There were two stent occlusions due to sludge formation, and two patients died during follow-up. CONCLUSION. Percutaneous intraductal microwave ablation of malignant biliary strictures is safe and feasible. Prospective randomized controlled studies with long-term results are warranted to determine the effectiveness of this technique in lengthening the stent patency period.


Subject(s)
Ablation Techniques , Biliary Tract Neoplasms/pathology , Biliary Tract Neoplasms/surgery , Cholestasis/pathology , Cholestasis/surgery , Microwaves/therapeutic use , Stents , Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Retrospective Studies
15.
Clin Neurol Neurosurg ; 193: 105778, 2020 06.
Article in English | MEDLINE | ID: mdl-32200216

ABSTRACT

OBJECTIVES: To investigate the effect of deep brain stimulation of the subthalamic nucleus (STN-DBS) and to compare low-frequency versus high-frequency STN-DBS on hemodynamic parameters of the middle cerebral artery between patients with advanced Parkinson's disease and age-sex matched healthy controls. PATIENTS AND METHODS: Eighteen patients with advanced Parkinson's disease (PD) with bilateral STN-DBS and 18 control subjects underwent Transcranial Doppler Ultrasound (TCDU) were included in the study. The hemodynamic parameters including blood flow velocity (FV), pulsatility index (PI) and, resistance index (RI) of the right middle cerebral artery (MCA) were measured and compared during the phases using TCDU. The first DBS-off, the second low-frequency DBS of 60 Hz, and the third high-frequency DBS of 130 Hz were compared. RESULTS: PD patients had significantly higher MCA-PI values compared with controls (0.99 ± 0.27 vs. 0.82 ± 0.14) (p = 0.031). Also, the MCA-PI values were higher in the low-frequency DBS (0.94 ± 0.14) and high-frequency DBS (0.93 ± 0.16) than in the controls (0.82 ± 0.14) (p = 0.022 and p = 0.041, respectively). There were no significant differences of FV and RI values among the DBS-on, DBS-off and, controls. The RI values were higher in the PD patients than in the controls, although these were not statistically significant. Also, PI values of the MCA decrease in different frequencies (60 Hz or 130 Hz). CONCLUSION: The results of this study showed that MCA-PI values are higher in advanced PD compared with controls. These indices indicate that MCA resistances and impedances are increased in advanced PD. Low- or high-frequency DBS treatment have beneficial effect to reduce high PI in advanced PD patients.


Subject(s)
Cerebrovascular Circulation , Deep Brain Stimulation/methods , Hemodynamics , Parkinson Disease/diagnostic imaging , Parkinson Disease/therapy , Subthalamic Nucleus/diagnostic imaging , Adult , Aged , Blood Flow Velocity , Female , Humans , Male , Middle Aged , Middle Cerebral Artery/physiopathology , Parkinson Disease/physiopathology , Ultrasonography, Doppler, Transcranial , Vascular Resistance
17.
CVIR Endovasc ; 2(1): 39, 2019 Nov 20.
Article in English | MEDLINE | ID: mdl-32026997

ABSTRACT

BACKGROUND: Hepatic arterioportal fistulas are rare, abnormal, direct communications between hepatic artery and portal venous system. Treatment options shifted from surgery to endovascular interventions. Catheterization may be challenging. We report a case of a hepatic arterioportal fistula treated successfuly with Amplatzer Vascular Plug II via percutaneous transhepatic hepatic artery access after failed transfemoral approach. CASE PRESENTATION: 58 year old woman presented with right heart failure, kidney insufficiency and massive ascites related to portal hypertension caused by hepatic arterioportal fistula. She had a history of previous abdominal surgery. Colour Doppler ultrasound and computed tomography revealed a giant portal vein aneurysm related to large hepatic areterioportal fistula. Endovascular treatment was planned. Catheterization of the hepatic artery could not be realized due to severe tortuosity and angulation of the celiac artery and its branches. Access to the hepatic artery was obtained directly via percutaneous transhepatic route and fistula site was embolized with Amplatzer Vascular Plug II and coils. Immediate thrombosis of the aneurysm sac and draining portal vein was observed. Patients clinical status improved dramatically. CONCLUSION: Transcatheter embolization is the first choice of the treatment of hepatic arterioportal fistulas but the type of the therapy should be tailored to the patient and interventional radiologist should decide the access site depending on his own experience if the routine endovascular access can not be obtained.

18.
Cureus ; 10(5): e2560, 2018 May 01.
Article in English | MEDLINE | ID: mdl-29974015

ABSTRACT

T-tubes have been used by surgeons for the decompression of the choledocus for over a hundred years. Errors in the operative technique and patient-related risk factors, such as immune comprehensive therapy, diabetes mellitus, steroid drug usage, T-tube morphology, T-tube material, and the T-tube extraction technique, are some of the factors that affect the risk of bile leak. In most cases, a surgical approach is required. Herein, we present a case of bile leak after T-tube removal and an unusual solution to this difficult complication.

19.
Turk Neurosurg ; 25(5): 695-700, 2015.
Article in English | MEDLINE | ID: mdl-26442533

ABSTRACT

AIM: Deep venous thrombosis (DVT) and pulmonary embolism (PE) are the most frequent surgical problems and associated with high morbidity and mortality. Neurosurgical patients constitute a unique group where prophylaxis with anticoagulant and antiaggregant agents are relatively contraindicated due to the natural course of vascular problems such as aneurysms, hemorrhagic tumors or hematomas or increased vulnerability to complex spinal surgeries and trauma. MATERIAL AND METHODS: We included 67 patients predicted to be immobilized for 2 or more months in this retrospective analysis. A vena cava filter was inserted between the first and seventh postoperative day in 40 patients in a prophylactic manner whereas 27 patients received low dose heparin for the same purpose. The patients were evaluated for symptomatic DVT or PE. RESULTS: Percutaneous insertion was performed for all filters without any complication. DVT occurred in two patients of the filter group and 1 patient of the heparin group. There was no PE recorded in any patient of either group. Patients were followed up for 22 months in the filter and 16 months in the heparin group. CONCLUSION: We conclude that prophylactic filter use in high risk neurosurgical patients is not beneficial and not superior to low-molecular-weight heparin use. Nevertheless, it is reasonable to prevent PE in patients with proven DVT who have no contraindication for anticoagulant drugs.


Subject(s)
Anticoagulants/therapeutic use , Heparin, Low-Molecular-Weight/therapeutic use , Vena Cava Filters , Venous Thromboembolism/prevention & control , Adult , Aged , Female , Humans , Immobilization/adverse effects , Male , Middle Aged , Neurosurgical Procedures/adverse effects , Postoperative Period , Pulmonary Embolism/prevention & control , Retrospective Studies , Venous Thrombosis/prevention & control
20.
Vector Borne Zoonotic Dis ; 14(11): 817-20, 2014 Nov.
Article in English | MEDLINE | ID: mdl-25409273

ABSTRACT

Crimean-Congo hemorrhagic fever (CCHF) is a fatal viral infection that involves multiple organs, and endothelium. We described abdominal sonographic findings of the patients infected with the Crimean-Congo hemorrhagic fever virus (CCHFV) in relation to the severity of the disease. This is a prospective study performed among hospitalized patients infected with CCHF between 2005 and 2011. A total of 210 hospitalized patients with confirmed CCHF infection were included in the study. The mean age was 47 and 49.5% of the patients were female. Patients were classified as mild, moderate, or severe disease according to their clinical and laboratory findings. The relationship between the clinical severity of CCHF and the abdominal sonographic findings was analyzed. Sonographic findings of abdomen included gallbladder wall thickening (GBWT) in 44 (21%), splenomegaly in 39 (19%), hepatomegaly in 52 (25%), decrease in echo of liver parenchyma in nine (4%), increase in echo liver parenchyma in 13 (6%), intra-abdominal fluid collection/ascites in 23 (11%), and enlarged periportal lymph nodes in seven (3%) cases. GBWT was detected in 3% of mild patients, 23% of moderate patients, and 61% of severe patients (p<0.001). In multivariate analysis to predict the severity, GBWT (odds ratio [OR] 5.4, confidence interval [CI] 1.76-16.49, p=0.003) and intra-abdominal fluid collection/ascites (OR 3.5, CI 1.07-12.61, p=0.049) were found to be significantly associated with disease severity. In conclusion, ultrasonography is a reliable, useful, and noninvasive diagnostic tool for evaluation of the abdominal findings of the patients with CCHFV infection. GBWT and intra-abdominal fluid collection/ascites were found to be predictors of severity.


Subject(s)
Abdomen/diagnostic imaging , Hemorrhagic Fever Virus, Crimean-Congo/physiology , Hemorrhagic Fever, Crimean/diagnostic imaging , Adolescent , Adult , Aged , Aged, 80 and over , Animals , Female , Hemorrhagic Fever, Crimean/diagnosis , Hemorrhagic Fever, Crimean/virology , Hospitals , Humans , Male , Middle Aged , Prospective Studies , Severity of Illness Index , Turkey , Ultrasonography , Young Adult
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