ABSTRACT
Fahr's disease is histopathologically characterized by massive bilateral calcifications of the cerebral basal ganglia, the dentate nuclei of the cerebellum and both the cerebral and cerebellar cortices. We report a case of Fahr's disease in which a 99mTc-hexamethyl-propylenamine oxime (99mTc-HMPAO) brain SPECT study was used to evaluate regional cerebral blood flow to the calcified regions. There was markedly decreased perfusion to the basal ganglia bilaterally as well as decreased perfusion to the cerebral cortices that correlated well with the patient's clinical condition.
Subject(s)
Basal Ganglia Diseases/diagnostic imaging , Brain/diagnostic imaging , Calcinosis/diagnostic imaging , Cerebrovascular Circulation/physiology , Adult , Basal Ganglia/diagnostic imaging , Cerebellar Nuclei/diagnostic imaging , Cerebral Cortex/diagnostic imaging , Humans , Male , Organotechnetium Compounds , Oximes , Technetium Tc 99m Exametazime , Tomography, Emission-Computed, Single-PhotonABSTRACT
Radiocolloid lymphoscintigraphy is a very effective diagnostic procedure for dynamic evaluation of lymphatic flow. In this case report, the use of radiocolloid lymphoscintigraphy in detection of a post-surgical lymphatic leak is presented. Dynamic pedal lymphoscintigraphy with Tc 99m-antimony trisulfide colloid clearly demonstrated the site of the leak.