ABSTRACT
Cancer is a complex disease that can affect different parts of the body. The rates of cancer have shown an increasing trend in the past decade. A majority of cancers are detected late, therefore becoming untreatable and resulting in significant mortality. Additionally, the lack of awareness about cancers, their risk factors, diagnostic modalities, and preventive measures contributes to increased burden among people. Despite significant developments in the therapeutic and comprehensive management of cancers, the cause for concern is the lack of medication adherence. This is majorly attributed to the adverse effects of the medication, the cost of the drugs, and other reasons. This review comprehensively discusses various aspects of cancer medication adherence that include therapeutic modalities for treating cancers, factors influencing medication adherence, barriers, and facilitators to medication adherence.
ABSTRACT
Karnataka state has the second highest rainfed agricultural land in India, where agricultural output relies heavily on rainfall. The Shimsha basin, a sub-basin of Cauvery in the state, comes under a semi-arid region and predominantly consists of rainfed agricultural land. Rainfall patterns have changed dramatically with time resulting in frequent floods and droughts. Understanding the spatiotemporal distribution of rainfall and its change patterns in the area would benefit sustainable agriculture planning and water resources management practices. The current study aims to determine the variability and trend in rainfall. The daily rainfall data of the Shimsha basin from 1989 to 2018 is collected, and the annual, seasonal, and monthly rainfall totals and the number of rainy days are derived. All the time series are subjected to statistical methods to examine rainfall variability and trend. The mean, standard deviation, coefficient of variation (CV), and Standardized Anomaly Index are used for the preliminary and variability analysis, while the coefficient of skewness and kurtosis are used to understand the rainfall distribution characteristics. The homogenous and serially independent series are identified by homogeneity and serial correlation tests. The trend in the homogenous and serially independent series is identified by Mann-Kendall and Spearman's rank correlation tests, while the magnitude of the trend is quantified using the Sen's slope technique, and the trend change point is evaluated using the sequential Mann-Kendall test. Based on the study, the average rainfall in the study area is 801.86 mm, with CV ranging from 43.3 to 22.27%. The southwest monsoon (SWM) season brings the greatest rain to the basin, followed by the post-monsoon (PM), summer, and winter seasons. In the annual time frame, except one station, all other stations have shown significant or insignificant increasing trends. The seasonal rainfall has shown insignificant rising trends during the summer and winter seasons while insignificant increasing and decreasing trends during the PM season. The SWM season has indicated significant increasing trends, insignificant increasing and decreasing trends. Overall, the study area has noticed an increased annual and seasonal rainfall except for the post-monsoon season, during which the rainfall showed a considerable decline. The findings of the study are helpful in water resource management, agricultural planning, and socioeconomic development in the study area.
Subject(s)
Agriculture , Rivers , India , Seasons , RainABSTRACT
Studies were carried out on the co-milling of wheat (W), green gram (GG) and barley (BR) grains using a roller milling system. The co-milled straight run flours obtained by varying proportions of wheat, barley and green gram WGGBR-1 (90:5:5), WGGBR-2 (80:10:10) and WGGBR-3 (70:15:15) were used in the cookie baking experiments. As the amount of GG and BR increased in blend, water absorption increased (56.5-58.4%) and dough stability and extensibility values decreased (104-92 mm). Hardness of cookie doughs and spread ratio (7.70-6.00) of cookies decreased and breaking strength values increased from 2900 to 3700 g in cookies made using co-milled blends WGGBR-1, WGGBR-2 and WGGBR-3. The highest breaking strength value (3700 g), large islands, gummy mouth feel and lowest overall quality score of 51.5 were recorded for cookies made with blend WGGBR-3 indicating that the cookies had unacceptable hard texture. The optimum blend for cookies was WGGBR-2 (80:10:10) and the cookies possessed slightly small islands, crisp, light texture and a pleasant taste. These cookies had 12.30 and 8.00% protein and dietary fibre as against the control cookie values of 8 and 4%, respectively. The in vitro protein digestibility of the control cookies was 61% and it was 51% for cookies made with WGGBR-2 blend.
