ABSTRACT
El déficit adquirido de zinc es un síndrome definido por la presencia de una triada: dermatitis, diarrea y alopecia junto a niveles de zinc en sangre pordebajo de la normalidad. El examen dermatológico muestra vesículas, ampollas y pústulas predominantemente en áreas periorificial y acral. Se produceuna respuesta clínica rápida, con remisión completa de las lesiones tras administración de preparados de zinc.Presentamos el caso de una mujer de 20 años de edad, con lesiones cutáneas típicas y bajos niveles de zinc en sangre, secundario a nutrición parenteraltotal en asociación con enfermedad de Crohn. El conocimiento de este síndrome y su diagnóstico nos conduce, a través de un tratamiento integral,a su resolución en un corto periodo de tiempo (AU)
Acquired zinc deficiency is a syndrome definied for a triad: dermatitis, diarrhoea and alopecia plus low plasma zinc level. Dermatologic examinationrevealed vesicles, blisters and pustules predominantly in periorificial and acral regions. A rapid clinical response will occur, with complete healing oflesions due to administration of a zinc preparation.A 20 years old woman, with typical skin lesions and low plasma zinc level, due to TPN (Total Parenterl Nutrition) in association with Crohns disease isreported. The knowledge of this syndrome and its diagnosis lead, through integrative therapy, to its resolution in a short time (AU)
Subject(s)
Humans , Male , Female , Adult , Zinc Deficiency , Crohn Disease/complications , Exanthema/etiology , Parenteral Nutrition, Total/adverse effects , Syndrome , Exanthema/diagnosis , Exanthema/drug therapy , Zinc/therapeutic useABSTRACT
Las complicaciones quirúrgicas son desvíos de la evolución esperada en la realización del acto quirúrgico. Ocurren como consecuencia de uno o varios sucesos inesperados que, en la mayoría de los casos, podrían evitarse con una planificación previa minuciosa, una atención máxima durante la cirugía y unos cuidados postoperatorios adecuados. Algunas complicaciones son vitales, como la aparición de arritmia cardíaca, anafilaxiao parada cardiorrespiratoria, y otras, derivadas directamente de la cirugía cutánea, pueden afectar al proceso de cicatrización y al aspecto estético final de la cicatriz. Por lo tanto, no solamente debemos tener una formación adecuada en cirugía cutánea, sino también en reanimación cardiopulmonar básica y avanzada. En esta revisión comentaremos las medidas perioperatorias necesarias para evitar la aparición de complicaciones en la cirugía dermatológica y definiremos las diferentes complicaciones que pueden aparecer tras la misma (AU)
Surgical complications are any deviation from the expected course of the surgical procedure. They occur as a consequence of one or more unexpected events, which can be avoided in the majority of cases through careful planning, a precise surgical technique, and correct postoperative care. Some complications, such as cardiac arrhythmias, anaphylaxis, and cardiorespiratory arrest, are life-threatening whereas others, occurring as a direct result of surgery, can affect the healing process and the final cosmetic appearance of thescar. We must therefore have not only the relevant training in dermatologic surgery, but also in basic and advanced cardiopulmonary resuscitation. In this review we discuss the perioperative measures necessary to avoid the onset of complications in dermatologic surgery and we define the various complications that candevelop (AU)
Subject(s)
Humans , Skin Diseases/surgery , Postoperative Complications/epidemiology , Intraoperative Care/methods , Surgical Wound Dehiscence/epidemiology , Surgical Wound Infection/epidemiology , Wound Healing/physiology , Granulation Tissue/physiopathologyABSTRACT
Surgical complications are any deviation from the expected course of the surgical procedure. They occur as a consequence of one or more unexpected events, which can be avoided in the majority of cases through careful planning, a precise surgical technique, and correct postoperative care. Some complications, such as cardiac arrhythmias, anaphylaxis, and cardiorespiratory arrest, are life-threatening whereas others, occurring as a direct result of surgery, can affect the healing process and the final cosmetic appearance of the scar. We must therefore have not only the relevant training in dermatologic surgery, but also in basic and advanced cardiopulmonary resuscitation. In this review we discuss the perioperative measures necessary to avoid the onset of complications in dermatologic surgery and we define the various complications that can develop.
Subject(s)
Postoperative Complications/etiology , Skin Diseases/surgery , Blood Coagulation , HumansABSTRACT
Severe combined immunodeficiency (SCID) is a heterogeneous group of disorders characterized by a defect of T and B cell immunity with a genetic origin in most cases. Although the X-linked recessive form is most common (60-70%), there are autosomal recessive forms (20%) and spontaneous mutations. While SCID may present with many nosocomial infections, dermatophyte infections are not common. We reported a case of SCID which was associated with a widespread skin infection with Trichophyton mentagrophytes.
Subject(s)
Severe Combined Immunodeficiency/complications , Tinea Capitis/complications , Antifungal Agents/therapeutic use , Female , Griseofulvin/therapeutic use , Humans , Infant , Tinea Capitis/drug therapyABSTRACT
No disponible
No disponible
Subject(s)
Humans , Male , Adult , Sturge-Weber Syndrome/complications , Neurofibromatosis 1/complications , Cafe-au-Lait Spots/pathologySubject(s)
Neurofibromatosis 1/complications , Sturge-Weber Syndrome/complications , Adult , Humans , MaleABSTRACT
La capecitabina es un agente antineoplásico utilizado para el tratamiento de pacientes con metástasis de tumores sólidos (mama y colon) en estadio avanzado. Se reconocen distintos efectos adversos, entre los cuales se encuentran los cutáneo-mucosos y, en concreto, la hiperpigmentación. Presentamos un caso de hiperpigmentación cutánea localizada secundaria a capecitabina en una mujer intervenida de cáncer de mama y en tratamiento durante un mes con este fármaco. El inicio del tratamiento se asoció con disestesias a nivel de manos y pies, así como aumento de la pigmentación de las mismas. La etiopatogénesis de tales manifestaciones es desconocida. Otros efectos adversos descritos, desde el punto de vista dermatológico, asociados a este fármaco asientan en uñas produciendo onicolisis, fragilidad, decoloración y distrofia
Capecitabine is an antineoplastic agent used for the treatment of patients with metastatic solid tumors (breast and colon). Different adverse effects have been recognized, among which we find the muco-cutaneous ones and, specifically, hyperpigmentation. We report a case of localized cutaneous hyperpigmentation secondary to capecitabine in a woman that underwent surgery for breast cancer and was receiving this drug for a month. The start of therapy was associated with dysesthesias and hyperpigmentation of the hands and feet. The pathogenesis of such manifestations is unknown. Other reported cutaneous adverse effects associated with this drug involve the nails producing onycholysis, fragility, discoloration and dystrophy
Subject(s)
Female , Middle Aged , Humans , Hyperpigmentation/chemically induced , Antineoplastic Agents/adverse effects , Antineoplastic Agents/therapeutic use , Breast Neoplasms/drug therapyABSTRACT
Capecitabine is an antineoplastic agent used for the treatment of patients with metastatic solid tumors (breast and colon). Different adverse effects have been recognized, among which we find the muco-cutaneous ones and, specifically, hyperpigmentation. We report a case of localized cutaneous hyperpigmentation secondary to capecitabine in a woman that underwent surgery for breast cancer and was receiving this drug for a month. The start of therapy was associated with dysesthesias and hyperpigmentation of the hands and feet. The pathogenesis of such manifestations is unknown. Other reported cutaneous adverse effects associated with this drug involve the nails producing onycholysis, fragility, discoloration and dystrophy.
