ABSTRACT
BACKGROUND: In 2008, members of the TEPARG provided first insights into the legal and ethical framework governing body donation in Europe. In 2012, a first update followed. This paper is now the second update on this topic and tries to extend the available information to many more European countries. METHODS: For this second update, we have asked authors from all European countries to contribute their national perspectives. By this enquiry, we got many contributions compiled in this paper. When we did not get a personal contribution, one of us (EB) searched the internet for relevant information. RESULTS: Perspectives on the legal and ethical framework governing body donation in Europe. CONCLUSIONS: We still see that a clear and rigorous legal framework is still unavailable in several countries. We found national regulations in 18 out of 39 countries; two others have at least federal laws. Several countries accept not only donated bodies but also utilise unclaimed bodies. These findings can guide policymakers in reviewing and updating existing laws and regulations related to body donation and anatomical studies.
Subject(s)
Tissue Donors , Tissue and Organ Procurement , Humans , Cadaver , Europe , Human BodyABSTRACT
The state of alarm due to Covid-19 pandemic in Spain stopped all educational and most university research activities. The Spanish Anatomical Society (SAE) Consensus Expert Group on Body Donations piloted a study based on a questionnaire to know the status of body donations and dissection activities during the lockdown, as well as the future implications of Covid-19 pandemic for body donation programs and anatomy teaching. The questionnaire results show that Spanish Universities refused body donations and stopped all dissection research and teaching. The Covid-19 expected influence on anatomy teaching was referred to the increase in teaching workforce and resources required to apply the new safety measures to future practical activities, as well as to prepare and adapt teaching material for online-only programs. The application of reinforced safety measures was expected to be perceived by the respondent's students as a gain in teaching quality, while the transformation of the anatomy courses in online-only programs will be perceived as a quality decrease. The respondent's concerns about future institutional implications of the pandemic were related to increased costs of the adaptation of the facilities and the reinforced preventive measures, as well as the eventual decrease in donations. The complete lockdown applied to dissection rooms was not justified by scientific evidence and represented a break of the confidence deposed in the institutions by the donors. A consensus is required for the adoption of a renewed, comprehensive protocol for present and future body donations including the evidence Covid-19 pandemic has contributed to create.
Subject(s)
Anatomy , COVID-19 , Anatomy/education , Cadaver , Communicable Disease Control , Dissection , Humans , Pandemics , SARS-CoV-2 , Spain , TeachingABSTRACT
Paragangliomas are tumors that arise in the extraadrenal paraganglia and result from migration of neural crest cells during embryonic development. Based on their anatomical distribution, innervation and microscopic structure, these tumors can be classified into interrelated families: branchiomeric paraganglia (related to the branchial clefts and arches), intravagal, aortic-sympathetic and visceral-autonomic. Head and neck paragangliomas belong mainly to the first two of these families. The present article is divided into two parts. The first part reviews the embryological origin of these tumors. Special emphasis is placed on the process of neurulation or neural tube formation, neurosegmentation (with a summary of the mechanisms involved in the initial segmentation of the neural tube and of the hindbrain and spinal medulla), and the development of the sensory placodes and secondary inductions in the cranial region. Subsequently, the neural crest is analyzed, with special attention paid to the cranial neural crest. The embryonogenesis of paragangliomas is also described. The second part describes the topographical distribution of head and neck paragangliomas according to their localization: jugulotympanic, orbit, intercarotid, subclavian and laryngeal. The embryonogenesis and most important anatomical characteristics are described for each type.
Subject(s)
Head and Neck Neoplasms/embryology , Head and Neck Neoplasms/pathology , Paraganglioma/embryology , Paraganglioma/pathology , Head and Neck Neoplasms/blood supply , Humans , Paraganglioma/blood supplyABSTRACT
Los paragangliomas son neoplasmas procedentes de paraganglios extra adrenales que derivan de la migración de las células de la cresta neural durante el desarrollo embrionario. Según su distribución anatómica, su inervación y su estructura microscópica, pueden ser agrupados en familias interrelacionadas, diferenciándose paraganglios branquioméricos (relacionados con los arcos y hendiduras branquiales),intravagales, aórtico-simpáticos y autonómicos-viscerales. Los paragangliomas cervicocefálicos pertenecen principalmente a las 2 primeras de estas familias. El presente capítulo está divido en 2 partes. En la primera parte se hace una revisión sobre su origen embriológico, poniendo especial énfasis en el proceso de neurulación o formación del tubo neural; la neurosegmentación, resumiendo los mecanismos implicados en la segmentación inicial del tubo neural y la segmentación del rombencéfalo y la médula espinal, y la evolución de las placodas sensitivas e inducciones secundarias en la región craneal. Posteriormente, se analiza la cresta neural, con especial atención a la cresta neural craneal, para terminar con la embriogénesis de los paragangliomas. En la segunda parte se desarrolla la distribución topográfica de los paragangliomas cervicocefálicos, diferenciándolos conforme a su localización: yúgulo-timpánicos, orbitarios, intercarotídeos, subclavios y laríngeos. Cada tipo se asocia con su embriogénesis y con los detalles anatómicos más relevantes (AU)
Paragangliomas are tumors that arise in the extra adrenalparaganglia and result from migration of neural crest cells during embryonic development. Based on their anatomical distribution, innervation and microscopic structure, these tumors can be classified into interrelated families: branchiomeric paraganglia (related to the branchial clefts and arches), intravagal, aortic-sympathetic and visceral-autonomic. Head and neck paragangliomas belong mainly to the first two of these families. The present article is divided into two parts. The first part reviews the embryological origin of these tumors. Special emphasis is placed on the process of neurulation or neuraltube formation, neurosegmentation (with a summary of the mechanisms involved in the initial segmentation of the neuraltube and of the hindbrain and spinal medulla), and the development of the sensory placodes and secondary inductions in the cranial region. Subsequently, the neural crest is analyzed, with special attention paid to the cranial neuralcrest. The embryonogenesis of paragangliomas is also described. The second part describes the topographical distribution of head and neck paragangliomas according to their localization: jugulotympanic, orbit, intercarotid, subclavian and laryngeal. The embryonogenesis and most important anatomical characteristics are described for each type (AU)
