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Biotechnol Lett ; 34(8): 1415-34, 2012 Aug.
Article in English | MEDLINE | ID: mdl-22526420

ABSTRACT

Clostridium spp. produce n-butanol in the acetone/butanol/ethanol process. For sustainable industrial scale butanol production, a number of obstacles need to be addressed including choice of feedstock, the low product yield, toxicity to production strain, multiple-end products and downstream processing of alcohol mixtures. This review describes the use of lignocellulosic feedstocks, bioprocess and metabolic engineering, downstream processing and catalytic refining of n-butanol.


Subject(s)
Biofuels , Butanols/metabolism , Industrial Microbiology/methods , Lignin/metabolism , Metabolic Engineering/methods , Clostridium/metabolism , Fermentation
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