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Orv Hetil ; 148(8): 339-42, 2007 Feb 25.
Article in Hungarian | MEDLINE | ID: mdl-17344156

ABSTRACT

In a retrospective study that included 66 homeless tuberculosis patients a local micro-epidemic was identified in the VIIIth district of Budapest with the highest tuberculosis incidence of the capital. Further molecular genetic characterization by IS 6110 fingerprinting, spoligotyping and mycobacterial inter-spread repetitive unit (MIRU) typing has shown that the observed micro-epidemic was due to a locally emerged, Budapest-specific lineage. The absence of infections with the more virulent Beijing genotype is also noteworthy. The findings indicate that tuberculosis control and prevention steps among the homeless need to be strengthened in Hungary.


Subject(s)
Bacterial Typing Techniques , Ill-Housed Persons/statistics & numerical data , Mycobacterium tuberculosis/genetics , Tuberculosis, Pulmonary/epidemiology , Tuberculosis, Pulmonary/microbiology , Bacterial Typing Techniques/methods , DNA Fingerprinting , DNA, Bacterial/isolation & purification , Humans , Hungary/epidemiology , Retrospective Studies
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