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Nucleosides Nucleotides Nucleic Acids
; 24(5-7): 725-8, 2005.
Article
in English
| MEDLINE
| ID: mdl-16248024
ABSTRACT
New enantiomeric isonucleoside analogues related to natural oxetanocin have been synthesized from D-glucosamine and D-glucose. The structures of the target compounds were confirmed by NMR, HRMS, UV, single crystal X-ray, and optical rotation data. Stability studies with respect to purine nucleoside phosphorylase and adenosine deaminase show that these compounds are not substrates. Antiviral results are discussed.