Importance of office hysteroscopy screening to diagnose endometrial carcinoma in menopausal women.

Uterine cancer is today the upcoming neoplasia in gynaecological oncology. In Western countries endometrial cancer is mostly diagnosed after menopause and often becomes apparent with atypical uterine bleeding. Because of the great importance of such disease a series of accurate diagnostic analyses which require an adequate expenditure by hospital structures become necessary. Transvaginal sonography (TVS) remains the first choice to diagnose atypical bleeding because it is less invasive and highly bearable by the patients. TVS exam allows the selection of all patients who have an endometrial thickness more than 5 mm and/or with an inhomogeneous endometrial line thickness, who would then undergo further analyses. To achieve the diagnosis, office hysteroscopy carried out in an outpatient departments, is the most useful exam. Such exam allows a complete overview of the uterine cavity with possible detection of smaller lesions and a specific sampling of histological material. Hysteroscopy is today an indispensable aid in last resort diagnosis of endometrial cancer and is highly tolerated by patients.

Intraocular lens implantation in Marfan's syndrome.

PURPOSE: To describe the results of the removal of ectopic lenses from patients with Marfan's syndrome using the scleral fixation method. METHODS: Intraocular lenses (IOLs) were implanted in six eyes affected by lens dislocation (ectopia lentis) using either the scleral fixation method (five eyes) or a silicone IOL in the capsular bag (one eye). Mean patient age ranged from 8-11 years and follow-up ranged from 7-20 months. RESULTS: Functional success was obtained in all eyes. Postoperative visual acuity was 20/20 to 20/40. One patient showed a dislocation of the IOL in the anterior chamber. In three eyes, an opacification of the posterior capsule was treated using an Nd:YAG laser. CONCLUSION: Intraocular lens implantation using the scleral fixation technique is the first choice in patients with Marfan's syndrome because it reduces the complications of IOL decentration.

Idiopathic chronic pigmentary purpura. Findings in 22 cases and proposal of a new classification.

22 cases of Idiopathic Chronic Pigmentary Purpura are described in 9 males and 13 females with an age range from 14 to 66. Clinical picture, morphology and distribution of the lesions varied. Laboratory and instrumental investigations excluded the presence of systemic diseases or toxic/pharmacological factors responsible for the purpuric eruption. On the basis of the clinical aspects and the histopathological results, an exclusively morphological classification of idiopathic purpuras in macular, papular and eczematic forms is proposed, maintaining that the old nosography is not justified and also taking into account the pathogenetic overlapping confirmed by recent immuno-histochemical and ultramicroscopical studies.

[Instrumental research of the functional character of the skin adnexa and microcirculation during chronic venous insufficiency]. / Recherche instrumentale du caractére fonctionnel des annexes cutanées et de la microcirculation au cours de l'insuffisance veineuse chronique (IVC).

We have led a microcirculatory and functional research of skin adnexa over 3 groups of 20 people each, who were affected with IVC at different grades and we have compared them to another group of 20 normal people. The microcirculatory researches (laser-Doppler, skin oximetry and thermometry) and functional ones of skin adnexa (sebometry and skin hydration) allowed us to get a nonunivocal behaviour between normal subjects and phlebopathies of I degree. For this reason, it is possible to consider these exams as screenings tests to determine the starting phases of phlebopathy, failing any skin marks. The reduced fluximetrical response taken by laser Doppler after postural variation and the reduction of hydration degree have been considered particularly significant.