[The virulence and cytochemical properties of Leishmania major during long-term cultivation]. / Virulentnost' i nekotorye tsitokhimicheskie kharakteristiki Leishmania major v protsesse dlitel'nogo kul'tivirovaniia.

It has been shown that morphogenesis of Leishmania major in each culture passage is characterised by the depletion of RNA and increase in its dispersion degree, by the change of the NADP-H-diaphorese, peroxidase and Janus green-B-oxidative activity in the promastigotes. Cytochemical peculiarities of invasive metacyclic promastigotes are an extreme depletion of RNA, its disperse form, a low activity of oxidative enzymes. This properties may manifest the pre-adaptation of Leishmania promastigotes to the development in vertebrate host. In the process of long-term cultivation of L. major the virulence, the metacyclogenesis, and the level of NADF-H-diaphorase and peroxidase activity decrease from passage to passage, but the ability to oxidate the Janus green-B increases.

[The epidemiological aspects of campylobacteriosis in children in arid area]. / Epidemiologicheskie aspekty kampilobakterioza u detei v aridnoi zone.

Specific epidemiological features of Campylobacter infection in children in Samarkand Province during the period of 1987-1990 are discussed. The specific proportion of this infection in the total structure of acute enteric infections was, on the average, 8.5%, and Campylobacter carriership among healthy children, 7.0%. Among children with Campylobacter infection, children aged up to 1 year constituted 71.5%. The results of the study of the biological properties of Campylobacter strains isolated from sick and healthy children and their difference from strains isolated in other regions are discussed.