[Characteristics of myocardial cholinergic innervation and its species differences]. / Osobennosti kholinergicheskoi innervatsii miokarda i ee vidovye razlichiia.

By means of some neuromorphological and physiological methods, peculiarities of the cardiac cholinergic innervation have been studied in the rabbit, guinea pig, cat, rat and man. The mammalian myocardium (the man including) is heterogeneous in its parasympathetic innervation. There are no terminal cholinergic plexuses in the external and medial layers of the myocardial ventricles, their density is not the same in other myocardial area. According to the cholinergic plexus density gradient, various parts of the atrial myocardium are distributed as following: the anterior part of the atrioventricular node and the atrioventricular fasciculus, the sinuatrial node area, the atrial septum, the right and left atria. Heterogeneity mentioned for the terminal cholinergic plexus demonstrates that various myocardial parts are not similarly subjected to the cholinergic influences.

[Age-related changes in the cholin- and adrenergic innervation of the human heart]. / Vozrastnye izmeneniia kholi- i adrenergicheskoi innervatsii serdtsa cheloveka.

The hearts of 35 patients of different age have been studied. The cholinergic innervation reaches full differentiation by the age of 30, its involution begins after 50. The adrenergic innervation is most manifest in children, its involution begins from 30. After 60 the nervous plexuses of the heart are fully devoid of catecholamines. The sensitivity of the myocardium to adrenalin at different age levels is roughly the same.