1.
Stomatologiia (Mosk)
; 69(3): 9-11, 1990.
Article
in Russian
| MEDLINE
| ID: mdl-2202091
ABSTRACT
Soluble and total protein content and cathepsin D activity were measured in rat mandibular bone tissue during healing of a fracture treated with proteolytic enzymes (andecalin) or protease inhibitors (contrykal) electrophoresis. Contrykal essentially elevated collagen content in mandibular bone tissue and reduced lysosomal enzymes activity. Andecalin had no noticeable effect on the levels of total protein and collagen, but it significantly increased the activity of cathepsin D. The findings evidence that local contrykal electrophoresis in the focus of injury creates an effective concentration of the drug that enhances the fracture healing and prevents the development of pyoinflammatory complications.
Subject(s)
Bone and Bones/metabolism , Cathepsin D/metabolism , Mandible/metabolism , Mandibular Fractures/metabolism , Proteins/metabolism , Animals , Bone and Bones/drug effects , Drug Evaluation, Preclinical , Female , Male , Mandible/drug effects , Mandibular Fractures/drug therapy , Peptide Hydrolases/therapeutic use , Protease Inhibitors/therapeutic use , Proteins/drug effects , Rats , Rats, Inbred Strains , Solubility , Wound Healing/drug effects , Wound Healing/physiology
2.
Stomatologiia (Mosk)
; 67(3): 4-6, 1988.
Article
in Russian
| MEDLINE
| ID: mdl-2457964
Subject(s)
Bone and Bones/drug effects , Mandibular Fractures/drug therapy , Minerals/metabolism , Protease Inhibitors/therapeutic use , Animals , Aprotinin/administration & dosage , Drug Combinations/administration & dosage , Drug Evaluation, Preclinical , Female , Iontophoresis , Male , Mandibular Fractures/physiopathology , Pancreatic Extracts/administration & dosage , Povidone/administration & dosage , Rats , Wound Healing/drug effects
3.
Stomatologiia (Mosk)
; 66(2): 36-8, 1987.
Article
in Russian
| MEDLINE
| ID: mdl-3472389
Subject(s)
Oroantral Fistula/surgery , Adult , Female , Humans , Male , Methods , Middle Aged , Preoperative Care , Surgical Flaps
4.
Stomatologiia (Mosk)
; 65(3): 51-2, 1986.
Article
in Russian
| MEDLINE
| ID: mdl-3523845
Subject(s)
Cleft Palate/surgery , Palate, Soft/surgery , Pharynx/surgery , Velopharyngeal Insufficiency/surgery , Adolescent , Adult , Female , Humans , Male , Reoperation , Surgical Flaps , Suture Techniques
5.
Stomatologiia (Mosk)
; 57(6): 30-4, 1978.
Article
in Russian
| MEDLINE
| ID: mdl-281026
6.
Stomatologiia (Mosk)
; 55(5): 33-7, 1976.
Article
in Russian
| MEDLINE
| ID: mdl-798348
Subject(s)
Bone Transplantation , Cleft Palate/surgery , Adolescent , Adult , Child , Child, Preschool , Female , Humans , Male , Methods , Osteotomy , Transplantation, Homologous
7.
Stomatologiia (Mosk)
; 54(6): 70-1, 1975.
Article
in Russian
| MEDLINE
| ID: mdl-1061360