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[A comparative analysis of the action of zootoxins on the isolated heart]. / Sravnitel'nyi analiz deistviia nekotorykh zootoksinov na izolirovannoe serdtse.

Val'tseva, I A; Krylov, V N; Egorov, V V; Sheshina, N P.

Nauchnye Doki Vyss Shkoly Biol Nauki ; (4): 47-53, 1991.

Article in Russian | MEDLINE | ID: mdl-1859858

ABSTRACT

A comparative analysis of cardiotropic activity of toxins has been studied in experiments on isolated heart of the poisonous animals from different systematic groups living on the territory of the USSR: reptiles (the venom of cobra, Vipera lebetina, Ancistrodon blomhoffi), amphibian (the venom of Bufo, Bombina, salamander), arachnids (the venom of Apis, Scolopendra, scorpion). The specific cardiotropic activity of the scorpion and Bufo venom has been discovered. The mechanisms of the cardiostimulative activity of scorpion venom have been found to be due to the activation of cellular adrenoreactive structures, and the Bufo venom to the activation of the intracellular calcium. The prospects of zootoxins using in cardiology for development of cardiotonic drugs and modelling the pathologic states in blood circulation system is substantiated.

Subject(s)

Cardiotonic Agents , Heart/drug effects , Toxins, Biological/pharmacology , Amphibian Venoms/pharmacology , Animals , Arthropod Venoms/pharmacology , Cats , Guinea Pigs , Heart/physiology , Heart Rate/drug effects , In Vitro Techniques , Myocardial Contraction/drug effects , Rats , Snake Venoms/pharmacology

[Evaluation of the possibility of determining the activity of the Willebrand factor using snake venoms from Soviet fauna]. / Otsenka vozmozhnosti opredeleniia aktivnosti faktora Villebranda s primeneniem iadov zmei otechestvennoi fauny.

Iakunin, G A; Val'tseva, I A; Smolianitskii, A Ia; Shumbalina, L F; Zille, L N.

Lab Delo ; (12): 717-20, 1981.

Article in Russian | MEDLINE | ID: mdl-6172640

Subject(s)

Blood Coagulation Factors/physiology , Elapid Venoms , Viper Venoms , von Willebrand Factor/physiology , Humans , Methods

[The influence of genotype on changes in serum protein composition of rats and their role in the development and manifestation of polymorphism in the body's protective-adaptive response]. / Vliianie genotipa na izmeneniia v belkovom sostave syvorotki krovi krys i ikh znachenie v vozniknovenii i proiavlenii polimorfizma zashchitno-adaptatsionnykh reaktsii organizma

Shchukin, P I; Val'tseva, I A; Novikova, A N; Kurilenko, N I; Il'ina, T I.

Izv Akad Nauk SSSR Biol ; (3): 406-18, 1975.

Article in Russian | MEDLINE | ID: mdl-1214025

Subject(s)

Blood Proteins , Genotype , Peritonitis/genetics , Polymorphism, Genetic , Animals , Peritonitis/blood , Rats , Species Specificity

[Biological reactions of the organism to the effects on the skin of laser rays]. / Biologicheskie reaktsii organizma pri vosdeistvii na kozhu lucha

Shakhtmeister, I Ia; Val'tseva, I A; Shekhter, A B; Iakunin, G A; Novikova, A N.

Vestn Dermatol Venerol ; (12): 7-12, 1974 Dec.

Article in Russian | MEDLINE | ID: mdl-4446750

Subject(s)

Lasers/adverse effects , Skin , Animals , Blood Cells , Blood Coagulation , Central Nervous System , Chlorobenzenes , Dermatitis/therapy , Dermatitis, Contact/therapy , Dogs , Helium , Laser Therapy , Lasers/instrumentation , Neon , Rabbits , Skin Ulcer/therapy

[Anticoagulant and toxic properties of various fractions of the venom of the Middle Asian cobra]. / Antikoaguliruiushchie i toksicheskie svoistva raalichnykh raktsii iada sredneaziatskoi kobry.

Barkagen, Z S; Val'tseva, I A; Mitel'man, L Sh; Talyzin, F F; Iagodkin, S I.

Izv Akad Nauk SSSR Biol ; 1: 116-25, 1967.

Article in Russian | MEDLINE | ID: mdl-5621069

Subject(s)

Anticoagulants , Venoms/toxicity , Animals , Rabbits , Snakes , Venoms/pharmacology

[The neutralizing effect of inhibitors of radical-chain processes (propygallate), heparin and hydrocortisone on the venom of Vipera lebetina]. / Obezvrezhivaiushchee deistvie ingibitorov radikal'no-tsepnykh protsessov (propilgallat), geparina i gidrokortizona na iad giurzy (Vipera lebetina)

Pavlovskii, E N; Talyzin, F F; Emanuel', N M; Val'tseva, I A; Pchelkina, A A; Iurkova, I B.

Zh Obshch Biol ; 27(3): 276-81, 1966.

Article in Russian | MEDLINE | ID: mdl-5999193

Subject(s)

Heparin/pharmacology , Hydrocortisone/pharmacology , Animals , Antivenins , Free Radicals/antagonists & inhibitors , Mice , Snakes

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