Cross-linking chitosan-Fe(III), an oral phosphate binder: studies in vitro and in vivo.

The objective was to evaluate the in vitro and in vivo phosphate binding properties of cross-linked chitosan iron (III) (CH-Fe(III)-CL), a potential oral phosphate binder for treating hyperphosphatemia. At equilibrium, the in vitro phosphate binding of CH-Fe(III)-CL was 23.6 mg g(-1) for simulated gastrointestinal conditions. In hyperphosphatemic rats, CH-Fe(III)-CL was similar to iron sulfate in reducing serum phosphate by about 35%.

[Economic and social recognition: where are we?]. / Riconoscimento sociale ed economico: a che punto siamo?

The Author analyses the contemporary Nursing working situation referring it to the economical point of view. A discussion is reported on the new working contract and on the future of professionals looking at the economical and jiuridical classification.