ABSTRACT
Objetivos : Determinar las características clínicas y epidemiológicas de niños con hipoplasia del timo y enfermedad respiratoria en Cuba. Material y Métodos : Estudio descriptivo retrospectivo en niños con edades comprendidas entre 1 y 6 años, de ambos sexos, atendidos en la consulta de Inmunología Pediátrica del Programa de Proyección Comunitaria del Municipio Arroyo Naranjo de La Habana o en la consulta de Inmunología Pediátrica del Hospital Materno Infantil Ángel Arturo Aballí Arellano del Municipio Arroyo Naranjo La Habana, entre los meses de septiembre 2019 y agosto 2022. Se incluyeron los niños con hipoplasia tímica y con antecedentes personales de enfermedad respiratoria infecciosa o no infecciosa diagnosticadas durante el período de estudio. Resultados : No se encontró relación entre la hipoplasia tímica y la edad o el sexo; se encontró mayor frecuencia de la hipoplasia tímica leve y moderada en niños con desarrollo de enfermedad respiratoria grave. Los factores con mayor frecuencia descritos en la enfermedad respiratoria complicada fueron la lactancia materna inefectiva, los antecedentes patológicos personales de atopia, el embarazo de riesgo, la prematuridad, el humo de tabaco en el ambiente y la asistencia a círculo infantil o a casa de cuidado infantil. Conclusiones : El desarrollo de hipoplasia tímica no mostró relación con la edad y el sexo. Se describieron varias condiciones con mayor frecuencia en niños con hipoplasia tímica y con enfermedad respiratoria complicada. La frecuencia de la hipoplasia tímica leve y moderada fue mayor en los pacientes con enfermedad respiratoria grave.
SUMMARY Objective : To determine the clinical and epidemiologic features of children with thymic hypoplasia and respiratory illnesses in Cuba. Methods : A retrospective study was conducted among children of 1-6 years of age of both sexes attended at a Pediatric Immunology Program of Hospital Materno Infantil Ángel Arturo Aballí Arellano in Habana, Cuba from September 2019 to August 2022. Children with thymic hypoplasia with and without a history of a respiratory illness either infectious or non-infectious were included. Results : No association between age and sex with thymic hypoplasia but an association was found with children with a severe respiratory illness. Factors associated with a severe respiratory illness were ineffective breastfeeding, history of an atopic condition, pregnancy of high risk, prematurity and exposure to tobacco smoke. Conclusions : Thymic hypoplasia was not associated with age or sex. An association with mild-moderate thymic hypoplasia was found with a severe respiratory illness.
Subject(s)
Humans , Male , Female , Child, Preschool , Pediatrics , Respiratory System , Respiratory Tract Diseases , Thymus Gland , Ultrasonography , Allergy and Immunology , CubaABSTRACT
Hematology and blood chemistry reference values in wildlife animals are considered a key element to evaluate their health and welfare status. The incidence of birds rescued is increasing, thus, rehabilitation centers worldwide need valid reference values to improve medical care for wild individuals. The objective of this study was to obtain the reference values of the adult black-faced ibis (Theristicus melanopis). Blood was taken from adult rehabilitated birds and analyzed to obtain red and white line values such as hematocrit, hemoglobin, mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), heterophils, lymphocytes, monocytes, eosinophils and basophils. Values for blood glucose, proteins, albumin, globulin, calcium, phosphorus, blood urea nitrogen (BUN), creatinine, alkaline phosphatase, aspartate aminotransferase (AST), gamma-glutamyl transpeptidase (GGT), lactate dehydrogenase (LDH), creatine phosphokinase (CPK) and albumin:globulin (A/G) ratio were also obtained. The results were similar to others reported for species of the Threskiornithidae family (bald, glossy and Puna ibises), but showed higher values for white blood cells (WBC), heterophils, monocytes and heterophil-lymphocyte (H/L) ratio, but lower values for basophils and eosinophils. Moreover, higher values in albumin, BUN and CPK were observed. This is the first report of the hematology references values for the black-faced ibis showing differences to other closely related species. The results may be of use in rescue and rehabilitation centers for animal welfare and health assessments of the black-faced ibis.
