ABSTRACT
Resumen ANTECEDENTES: en 80% de las ocasiones el cáncer de ovario epitelial se diagnostica en etapas III y IV, la recurrencia locorregional es una característica frecuente en esta neoplasia maligna. La mortalidad asociada es una de las más importantes de todas las neoplasias malignas en la mujer, en todo el mundo. OBJETIVO: documentar las metástasis de cáncer de ovario a piel, la incidencia, presentación clínica, y pronóstico. CASO CLÍNICO: paciente de 67 años, con un carcinoma seroso papilar etapa IIIC de ovario; se efectuaron cirugía óptima y cuatro ciclos de quimioterapia (carboplatino y paclitaxel), con 21 meses de intervalo libre de enfermedad. La paciente tenía: pápulas y nódulos inexplicables en la piel del abdomen y las piernas. La biopsia incisional documentó la recaída a la piel, sin otro sitio de metástasis a distancia. La paciente recibió tratamiento sistémico paliativo. CONCLUSIONES: las metástasis cutáneas de cáncer de ovario tienen una presentación clínica pleomórfica y distribución amplia en todo el organismo, con frecuencia afectan la región abdominal o torácica; las metástasis cutáneas de ovario tienen una expectativa de vida limitada, a pesar del tratamiento sistémico.
Abstract BACKGROUND: 80% of the cases of epithelial ovarian cancer are diagnosed in stages III and IV, locoregional recurrence is a frequent feature of this malignant neoplasm. Associated mortality is one of the most important of all malignant neoplasms in women, all over the world. OBJECTIVE: To document the metastasis of ovarian cancer to skin, incidence, clinical presentation, and prognosis. CLINICAL CASE: 67-year-old patient with papillary serous carcinoma stage IIIC of ovary; Optimal surgery and four cycles of chemotherapy (carboplatin and paclitaxel) were performed, with a 21-month disease-free interval. The patient had unexplained papules and nodules on the skin of the abdomen and legs. Incisional biopsy documented relapse to the skin, with no other site of distant metastases. The patient received systemic palliative treatment. CONCLUSIONS: Cutaneous metastases from ovarian cancer have a pleomorphic clinical presentation and widespread distribution throughout the body, often affecting the abdominal or thoracic region; cutaneous ovarian metastases imply a limited life expectancy, despite systemic treatment.
ABSTRACT
The mortality, incidence, morbidity, partial data and opportune detection, of the main cancer types were reviewed from de information register corresponding to 1987, to analyze the epidemiological panorama of cancer in Mexico. The main causes of death in women were cervix uterine, breast, stomach and lung carcinomas, leukemias and lymphomas; and in men were lung, gastric, prostate, leukemias and lymphomas. The most frequent localization of women's new cancer cases were cervix uterus, breast, ovary, lymphoma, thyroid gland and endometrium; and in men were prostate, lymphoma, stomach, leukemia and lung. In according to tendencies about the main death rates in Mexico, we estimate that 55.3 by 100.00 inhabitants will be the rate of cancer deaths in the year 2000, numerical character virtually bigger considering demographic variation like human life's hope and increase population with cancer risk.
Subject(s)
Neoplasms/epidemiology , Adult , Aged , Cause of Death , Female , Humans , Incidence , Male , Mexico/epidemiology , Middle Aged , Neoplasms/mortality , Registries/statistics & numerical data , Sex FactorsABSTRACT
1,200 cases of bone tumors were reviewed from the Orthopedic Hospital "Magdalena de las Salinas" between 1982 and 1989. 66.7% of them were benign tumors, 14.3% pseudotumoral lesions, 10.1% metastatic tumors, 8.6% primary malignant tumors, and 0.3% were malignant invasive tumors to bone. The most frequently found benign tumors were: osteochondroma, enchondroma and giant cell tumor; the most frequent pseudotumoral lesions were metaphyseal fibrous defects, solitary bone cysts and fibrous dysplasia; the most frequent primary malignant tumor was osteosarcoma. Prevalence, frequency, distribution, sex, most frequent ages, affected bones, multicentricity, and aggregated fractures, as well as the site of the primary lesion in metastatic and invading tumors, were similar to those reported in the classical series.
