[Magnesium orotate in treatment of chronic hypertension in pregnant women].

We examined 150 pregnant women with essential hypertension (EHT), EHT and connective tissue dysplasia (CTD), and healthy. Presence of CTD aggravated clinical picture of EHT and was associated with pronounced cardialgic, neurological, asthenic, vertebrogenic, visceral, and other syndromes. The use of antihypertensive, metabolic (magnesium orotate) drugs, sedative and uroseptic phytotherapy, application of other nondrug measures in conditions of multidisciplinary dynamic support of the gestational period facilitated regress of clinical symptoms of EHT and EHT+CTD, favorable course of pregnancy and successful delivery.

[Structure of cardiovascular pathology in pregnant women and efficacy of regional specialized management].

From 2000 to 2011 in prospective and retrospective studies we investigated pregnancy outcomes in all 30417 women treated within framework of the multidisciplinary management system for pregnant patients with cardiovascular diseases (hypertension, structural heart disease, aortic pathology and inflammatory autoimmune rheumatic diseases) designed and conducted in the Udmurt Republic of Russian Federation in late 1980-th. The system comprises specialized outpatient and inpatient departments, sanatorium and a maternity hospital at the regional cardiological center and provides ambulatory and hospital management and rehabilitation. Perinatal mortality decreased 65.8% from 11.1% in 2000 to 3.8% in 2011. Within 20 years no mother died.

[Cardiac angiosarcoma in a pregnant women].

We present a case of cardiac angiosarcoma in a pregnant women. Clinical manifestations of angiosarcoma were unspecific and progressed rapidly as hemopericardium, cardiac tamponade, heart failure, fever, chest pain. Pregnancy was interrupted at 22-nd week. The patient died in 6 months after appearance of first symptoms.

[Experience in using helium-neon laser irradiation alone and in the combined therapy of myocardial infarct and other forms of IHD]. / Opyt primeneniia gelii-neonovogo lazernogo oblucheniia i kompleksnoi terapii na ego osnove pri infarkte mickarda i drugikh formakh IBS.

349 chronic sufferers from coronary heart disease (functional class II-IV) were exposed to He-Ne laser radiation, received alpha-tocopherol acetate, solcoseryl, mildronate. Alleviation of pain syndrome, quicker increase of exercise tolerance were observed in patients treated with combined regimens: i.v. laser radiation+alpha-tocopherol acetate, i.v. laser therapy+alpha-tocopherol acetate+solcoseryl. Solcoseryl proved efficient against arrhythmia, positive trends in lipid peroxidation were observed in the use of preradiation antioxidants. It is thought valid to use drug "protection" in laser therapy of CHD, especially in growing intensity of the exposure and power of the beam, to control parameters of coagulation, hemostasis, microcirculation and lipid peroxidation.

[The use of kontrikal in treating unstable stenocardia by specialized first-aid teams]. / Primenenie kontrikala pri lechenii nestabil'noi stenokardii spetsializirovannymi brigadami skoroi pomoshchi.

The paper presents the results of unstable angina pectoris treatment in 121 patients who received or did not receive (65 and 56 patients, respectively) contrykal in a dose of 20,000 units as an adjuvant to standard treatment (analgetics, tranquilizers, vasodilators). All the patients were admitted to cardiological departments. The comparative assessment of the data favours contrykal infusions in emergency prehospital care of developing unstable angina pectoris. The drug produces a cardioprotective effect reducing the risk of macrofocal myocardial infarction.

[Use of contrykal in intensive care of myocardial infarct during the prehospital stage]. / Primenenie kontrykala v intensivnoi terapii infarkta miokarda na dogospital'nom étape.

The effect of contrykal was evaluated in 146 male patients with first myocardial infarction and 116 control patients in the prehospital period. Intravenous contrykal was given in a single dose of 20,000 IU within 30 to 360 minutes of onset of myocardial infarction, followed by intravenous administration of heparin, 10,000-15,000 U. The control patients received conventional therapy. Earlier application of contrykal contributed to attenuation of clinical manifestations of myocardial infarction. The drug was found to produce a clear-cut antianginal effect. It also exerted a positive action on the abdominal syndrome. There was a rapid inverse dynamics in ECG changes, fermentaemia (aspartate aminotransferase and alanine aminotransferase), decreased myocardial necrotic mass.