Impact of the 2005 and 2010 Spanish smoking laws on hospital admissions for tobacco-related diseases in Valencia, Spain.

OBJECTIVES: This study aimed to assess the impact of the latest smoke-free legislation on hospital admission rates due to smoking-related diseases in Spain. STUDY DESIGN: A retrospective cohort study was conducted to evaluate changes in hospital admission rates for cardiovascular, respiratory diseases, and smoking-related cancer in Valencia, Spain, during the period 1995-2013. Law 28/2005 and then law 42/2010 prohibited smoking in bars and restaurants as well as playgrounds and access points to schools and hospitals. METHODS: General population data by age and sex were obtained from the National Institute of Statistics census. Data on hospital admissions were obtained from the Minimum Basic Data Set. Diagnoses were codified according to the International Classification of Diseases-9th revision. Data from all hospitals of the Valencian Community from 1995 to 2013 were analysed. Trend analyses in the periods before and after the approval of the 2005 law were conducted using least-squares linear regression models. RESULTS: Adjusted hospital admission rates per 100,000 inhabitants for cardiovascular diseases significantly decreased after the 2005 Law (from 550.0/100,000 in 2005 to 500.5/100,000 in 2007), with a further decrease (to 434.6/100,000) in 2013, after the 2010 Law. Reductions in hospital admissions were seen in men and women, although declining trends were more marked in men. Hospital admission rates for respiratory diseases showed a reduction of a lower magnitude, whereas for smoking-related cancer admissions there was a slight decline only among men. CONCLUSIONS: The Spanish comprehensive smoking ban resulted in a remarkable reduction of the adjusted rate of hospital admissions mainly associated to cardiovascular diseases. The decrease in the number of persons requiring in-patient care is relevant and may be viewed as an improvement of the public's health.

Variabilidad de la práctica clínica para la enfermedad pulmonar obstructiva crónica en consultas externas / Variability in clinical practice for chronic obstructive pulmonary disease in outpatient clinics

OBJETIVOS: hasta el momento no existen trabajos de auditorías clínicas que evalúen la práctica clínica en la enfermedad pulmonar obstructiva crónica (EPOC) en el ámbito de consultas externas. El presente trabajo es un primer proyecto piloto que tiene por objetivo evaluar la variabilidad de la práctica clínica para la EPOC en este ámbito asistencial. MÉTODO: proyecto piloto de auditoría de historias clínicas llevada a cabo en consultas externas de Neumología en 9 hospitales públicos de Andalucía entre octubre 2013 y septiembre 2014. El objetivo era auditar 80 casos por centro, repartidos durante los 4 trimestres del año. La información se recogió mediante cuestionario estandarizado con 182 variables. Los datos se describen con medias y rangos interhospitalarios para evaluar la variabilidad. RESULTADOS: durante el año de estudio se analizaron 621 historias. Los pacientes eran mayoritariamente hombres, en la séptima década de la vida, con un porcentaje de fumadores activos del 26,2%, un considerable número de comorbilidades y mayoritariamente del ámbito urbano. Los datos indican que la atención sanitaria es en general correcta como promedio, pero indicando áreas de mejora en algunos puntos y una considerable variabilidad entre centros con diferencias significativas (p <0,001) para los cambios intercentro de la mayoría de las variables. CONCLUSIONES: la atención sanitaria al paciente con EPOC en consultas externas de Neumología en Andalucía muestra una considerable variabilidad que probablemente no pueda ser explicada sólo por la condición clínica del paciente. Estudios futuros deberán dilucidar qué factores inciden en esta variabilidad

OBJECTIVES: To date, there have been no clinical audits that evaluate clinical practice for chronic obstructive pulmonary disease (COPD) in outpatient clinics. This study is the first pilot project that aims to evaluate the variability in clinical practice for COPD in this healthcare setting. METHOD: A medical history audit pilot project carried out in outpatient pulmonology clinics in 9 public hospitals in Andalusia from October 2013 to September 2014. The objective was to audit 80 cases per center, distributed across the 4 quarters of the year. Information was collected using a standardized questionnaire with 182 variables. Data is described as averages and inter-hospital ranges to evaluate variability. RESULTS: 621 histories were analyzed during the year of the study. Patients were primarily male, in the seventh decade of life, 26.2% were active smokers, there were a considerable number of comorbidities and subjects lived in mainly urban areas. Data indicates that healthcare is generally appropriate on average, but there are areas of improvement in some points and there is a considerable variability between centers with significant differences (p <0.001) for inter-center changes for the majority of variables. CONCLUSIONS: Healthcare for patients with COPD in outpatient pulmonology clinics in Andalusia shows considerable variability that likely cannot be explained solely by the patient's clinical condition. Future studies must clarify what factors come into play in this variability

Size-dependent trapping behavior and optical emission study of NaYF4 nanorods in optical fiber tip tweezers.

Trapping of NaYF4:Er/Yb/Gd nanorods using an original optical fiber-tip tweezers is reported. Depending on their length, nanorods are reproducibly trapped in single or dual fiber tip configurations. Short rods of 600 nm length are trapped with two fiber tips facing each other. In contrary, long rods (1.9 µm) can be stably trapped at the apex of one single fiber tip and at a second stable trapping position 5 µm away from the tip. The up-conversion emission of trapped long nanorods is studied as a function of the position on the nanorod and in three orthogonal directions. The experimental results are discussed using numerical simulations based on exact Maxwell Stress Tensor approach.

Recomendaciones sobre el diagnóstico y manejo de la enfermedad pleural y pulmonar por asbesto / Recommendations for the diagnosis and management of asbestos-related pleural and pulmonary disease

Asbesto, también conocido en España como amianto, es el término utilizado para nombrar a un conjunto de silicatos minerales que suelen romperse en fibras. Su uso ha comportado la aparición de numerosas enfermedades, especialmente pleuropulmonares, todas ellas caracterizadas por su prolongada latencia. El asbesto es, además, un carcinógeno del grupo IA reconocido por la OMS desde 1987. En España está prohibido desde 2002. La publicación en 2013 de la 3.ª edición del protocolo de vigilancia sanitaria específica del amianto junto con la aparición de nuevas técnicas diagnósticas han motivado al grupo EROM de SEPAR a promover la elaboración de esta normativa que revisa aspectos clínicos, radiológicos y funcionales de las diferentes enfermedades relacionadas. También establece recomendaciones para el diagnóstico y seguimiento de los pacientes expuestos. Dichas recomendaciones han sido establecidas mediante sistema GRADE.(AU)

Asbestos is the term used for a set of mineral silicates that tend to break up into fibers. Its use has been associated with numerous diseases affecting the lung and pleura in particular, all of which are characterized by their long period of latency. Asbestos, moreover, has been recognized by the WHO as a Group IA carcinogen since 1987 and its use was banned in Spain in 2002. The publication in 2013 of the 3rd edition of the specific asbestos health monitoring protocol, together with the development of new diagnostic techniques, prompted the SEPAR EROM group to sponsor publication of guidelines, which review the clinical, radiological and functional aspects of the different asbestos-related diseases. Recommendations have also been made for the diagnosis and follow-up of exposed patients. These recommendations were drawn up in accordance with the GRADE classification system.(AU)

Neumonía familiar grave con aislamiento de Streptococcus pneumoniae / No disponible

Introducción: Presentamos una agregación intrafamiliar de neumonía grave, con aislamiento de Streptococcus pneumoniae en la esposa. Caso 1: Hombre de 54 años, ingresa el 27 de julio por dolor torácico y fiebre. Radiografía de tórax consolidación LID. Microbiología: antígenos urinarios negativos. Hemocultivos y cultivo de esputo negativos. A las pocas horas es trasladado a Cuidados Intensivos por shock séptico. Se instauró levofloxacino y ceftriaxona. Fiebre persistente, que mejoró tras la administración de vancomicina. Evolución favorable. Caso 2: Mujer de 50 años, esposa del caso 1, consulta el 31 de julio por fiebre y tos. Rx tórax condensación alveolar basal bilateral, pequeño derrame pleural derecho. Microbiología: antígeno neumococo en orina positivo, Streptococcus pneumoniae serotipo 1 en los hemocultivos. Toracocentesis exudado pleural con pH 7,46, cultivo negativo. Presentó hipotensión, oliguria, sepsis grave, e ingreso en UCI el mismo día del ingreso. Inicialmente se trata con ceftriaxona y azitromicina. Por persistencia de la fiebre, posteriormente con levofloxacino y vancomicina, con recuperación. Conclusiones: Presentamos un brote familiar de neumonía grave con aislamiento de neumococo serotipo 1

Introduction: We present a case of family aggregation of severe pneumonia with Streptococcus pneumoniae isolation in wife. Case 1: A 54 year old man was admited on July 27 for chest pain and fever. The chest radiograph LID consolidation. Microbiology: Streptococcus pneumoniae urinary antigens and Legionella pneumophila serogroup 1: negative. Negative blood cultures and sputum culture. A few hours later he was transferred to intensive care from septic shock. It was established antibiotic therapy with levofloxacin and ceftriaxone. He had persistent fever despite antibiotic, which improved after administration of vancomycin. Favorable clinical evolution. Case 2: 50 year old woman, wife of case 1, consulting on July 31 with fever and cough. The Rx chest bilateral basal alveolar condensation, small right pleural effusion. Microbiology: positive urine pneumococcus antigen, was isolated Streptococcus pneumoniae serotype 1 in blood cultures. Thoracentesis pleural exudate with pH 7.46, negative culture. He presented hypotension, oliguria, severe sepsis, and ICU admission the day of admission. Initially it treated with ceftriaxone and azithromycin. By persistent fever, later with levofloxacin and vancomycin, with recovery. Conclusions: We present a family outbreak of severe pneumonia with pneumococcal serotype 1 isolation

Empiema pleural por Actinomyces meyeri. Un nuevo caso / No disponible

Varón de 23 años que ingresa por presentar dolor costal izquierdo de dos semanas de evolución, tos y sudoración nocturna. Entre los antecedentes, fumador de 15 cigarrillos al día, consumo esporádico de alcohol, deportista aficionado al boxeo y traumatismo craneoencefálico 6 años antes por accidente doméstico. En la exploración física, temperatura 39°C. En el análisis de sangre, leucocitos 21.890/μL, neutrófilos 90%, proteína C reactiva 246,8 mg/L. La radiografía de tórax presentaba un pequeño derrame pleural izquierdo. En la toracocentesis, líquido pleural amarillento, exudado de predominio polinuclear (neutrófilos 93%), ADA 93 U/L, glucosa 1 mg/dL, pH 6,8. La citología resultó negativa y en el cultivo bacteriológico del líquido pleural se aisló Actinomyces meyeri. Al día siguiente a la hospitalización presentó empeoramiento del derrame pleural, con empiema masivo tabicado. Se indicó tratamiento antibiótico con amoxicilina/ácido clavulánico (intravenoso 14 días y oral 30 días), drenaje torácico y uroquinasa intrapleural, con recuperación completa

A 23 year old male was admitted to hospital two weeks left to submit evolution, coughing and night sweats rib pain. The background, smoking 15 cigarettes a day, occasional consumption of alcohol, boxing fan and athlete head injury six years ago by domestic accident. On physical examination, temperature 39°C. In the blood, leukocytes 21,890/PL, 90% neutrophils, CRP 246.8 mg/L. Chest radiography showed a small left pleural effusion. In thoracentesis, pleural fluid yellowish exudate polynuclear predominance (93% neutrophils), ADA 93 U/L, glucose 1 mg/dL, pH 6.8. The cytology negative bacterial culture and pleural fluid Actinomyces meyeri was isolated. The day after hospitalization presented worsening pleural effusion, with partitioning massive empyema. Antibiotic treatment was indicated with amoxicillin/clavulanate acid (intravenous 14 days and oral 30 days), thoracic drainage and intrapleural urokinase, with complete recovery

Biodiesel production from crude Jatropha oil catalyzed by non-commercial immobilized heterologous Rhizopus oryzae and Carica papaya lipases.

The aim of this study was to evaluate the feasibility of biodiesel production by transesterification of Jatropha oil with methanol, catalyzed by non-commercial sn-1,3-regioselective lipases. Using these lipases, fatty acid methyl esters (FAME) and monoacylglycerols are produced, avoiding the formation of glycerol as byproduct. Heterologous Rhizopus oryzae lipase (rROL) immobilized on different synthetic resins and Carica papaya lipase (rCPL) immobilized on Lewatit VP OC 1600 were tested. Reactions were performed at 30°C, with seven stepwise methanol additions. For all biocatalysts, 51-65% FAME (theoretical maximum=67%, w/w) was obtained after 4h transesterification. Stability tests were performed in 8 or 10 successive 4h-batches, either with or without rehydration of the biocatalyst between each two consecutive batches. Activity loss was much faster when biocatalysts were rehydrated. For rROL, half-life times varied from 16 to 579h. rROL on Lewatit VPOC 1600 was more stable than for rCPL on the same support.

Evaluation of emerging contaminants in a drinking water treatment plant using electrodialysis reversal technology.

Emerging contaminants (EC) have gained much attention with globally increasing consumption and detection in aquatic ecosystems during the last two decades from ng/L to lower ug/L. The aim of this study was to evaluate the occurrence and removal of pharmaceutically active compounds (PhACs), endocrine disrupting chemicals (EDCs) and related compounds in a Drinking Water Treatment Plant (DWTP) treating raw water from the Mediterranean Llobregat River. The DWTP combined conventional treatment steps with the world's largest electrodialysis reversal (EDR) facility. 49 different PhACs, EDCs and related compounds were found above their limit of quantification in the influent of the DWTP, summing up to a total concentration of ECs between 1600-4200 ng/L. As expected, oxidation using chlorine dioxide and granular activated carbon filters were the most efficient technologies for EC removal. However, despite the low concentration detected in the influent of the EDR process, it was also possible to demonstrate that this process partially removed ionized compounds, thereby constituting an additional barrier against EC pollution in the product. In the product of the EDR system, only 18 out of 49 compounds were quantifiable in at least one of the four experimental campaigns, showing in all cases removals higher than 65% and often beyond 90% for the overall DWTP process.

Neumonía por citomegalovirus en un adulto inmunocompetente / No disponible

No disponible

Comparación entre la prueba de marcha de 6 minutos y la prueba de esfuerzo cardiopulmonar en pacientes con hipertensión arterial pulmonar / Comparison between 6 minutes walking test and cardiopulmonary exercise test in patients with arterial pulmonary hypert tension

OBJETIVO: evaluar la relación existente entre la distancia caminada en la PM6M y la capacidad de ejercicio determinada por la PECP máxima en pacientes con HAP. MATERIAL Y MÉTODOS: estudio prospectivo de pacientes diagnosticados de HAP, a los que se les realizaron en el mismo día exploración funcional respiratoria completa, PM6M y, tras una hora de reposo, el mismo día, se procedió a realizar la PECP en bicicleta ergométrica, mediante protocolo incremental limitado por síntomas, con medición de parámetros de intercambio gaseoso, ventilatorios y cardiológicos. RESULTADOS: se evaluaron 39 pruebas realizadas durante los últimos 6 años. 34 de ellas (89,7%) fueron realizadas por mujeres. La edad media de los pacientes fue de 45,02 ± 10,5 años. Las pruebas fueron realizadas por 12 pacientes con HAP. Tres tenían HAP idiopática, 5 secundaria a conectivopatía, 2 secundaria a cortocircuitos sistémico-pulmonar corregidos y 2 a HAP secundaria a infección por VIH. La distancia media recorrida en la PM6M fue de 458,4 ± 85,4 metros. Existió una correlación directa significativa entre la distancia recorrida en la PM6M y el VO2p, AT, la carga máxima en watios, la VE, VT final, SpO2 inicial y final, FC final, el VO2/FC y Qtc final. La distancia recorrida también tuvo una correlación inversa significativa con la clase funcional medida mediante la escala NYHA, el VE/VCO2 y la FR y FC iniciales. CONCLUSIONES: la PM6M es una prueba de esfuerzo submáxima que refleja la capacidad de ejercicio determinada por la prueba de esfuerzo cardiopulmonar máxima en pacientes con hipertensión arterial pulmonar

OBJECTIVE: to assess the relationship between the distance walked during the 6MWT and exercise capacity determined by maximal CPET in patients with PAH. MATERIAL AND METHODS: prospective study in patients with PAH, that underwent complete pulmonary function test, standardized 6MWT and after an hour of rest, the same day, an incremental symptom-limited CPET on cycle ergometer, with measurement of ventilatory and cardiac parameters and gas analysis. RESULTS: thirty nine tests were performed during the last 6 years. 34 (89.7%) tests were performed by women. The mean age of the patients was 45.02 ± 10.5 years. The tests were performed by 12 patients. Three patients had idiopathic PAH, 5 PAH secondary to connective disease, 2 secondary to corrected congenital systemic-to-pulmonary shunts, and 2 secondary to HIV infection. The mean distance walked in the 6MWT was 458.4 ± 85.4 meters. There was a significant direct correlation between the distance walked in the 6MWT and VO2p, AT, the maximum load in watts, VE, final VT, initial and final SpO2, final HR, VO2/HR and final Qtc. The distance walked in the 6MWT had a significant inverse correlation with the functional class measured by the NYHA scale, VE/VCO2 and initial BR and HR. CONCLUSION: the 6MWT is a submaximal exercise test that reflects exercise capacity determined by maximal cardiopulmonary exercise testing in patients with pulmonary arterial hypertension

Neumonitis linfocitaria en la colitis ulcerosa. Presentación de un caso y revisión de la literatura / No disponible

La colitis ulcerosa (CU) afecta sobre todo al tubo digestivo distal, aunque debe ser considerada un trastorno sistémico, ya que puede presentar síntomas extraintestinales que tienen un impacto importante en la morbi-mortalidad de los pacientes. Las complicaciones pulmonares pueden comprometer el parénquima pulmonar, el árbol bronquial y la pleura. La prevalencia y etiología de estas lesiones son desconocidas, no siempre se asocian a la actividad de la enfermedad. Pueden presentarse de forma sintomática o asintomática. Los casos publicados sobre afectación pulmonar en la CU son excepcionales, por lo que presentamos el caso de un varón con diagnóstico de colitis ulcerosa que desarrolló un cuadro de neumonitis linfocitaria, con clínica de fiebre, tos y expectoración, e infiltrados pulmonares bilaterales en la radiografía y en la TAC de tórax. El lavado broncoalveolar presentaba predominio de linfocitos. La biopsia transbronquial descartó la NOC. Se descartó la toxicidad por fármacos. Se prescribe corticoide con evolución favorable

Ulcerative colitis (UC) affects mainly the digestive tract distal, although it should be considered a systemic disorder and extraintestinal symptoms may have a major impact on morbidity and mortality of patients. Pulmonary complications may compromise the lung parenchyma, the bronchial tree and pleura. Prevalence and etiology of these lesions is unknown, is not always associated with disease activity. There may be symptomatic or asymptomatic form. The reported cases of pulmonary involvement in UC are exceptional, so we present the case of a man diagnosed with ulcerative colitis who developed lymphocytic pneumonitis with clinical signs of fever, cough and expectoration. The chest radiograph and TAC showed alveolar infiltrates bilateral. Bronchoalveolar lavage showed lymphocyte predominance. Transbronchial biopsy ruled out the NOC. Was discarded drug toxicity. Corticosteroid is prescribed with favorable evolution

Optical binding of cylinder photonic molecules in the near field of partially coherent fluctuating Gaussian Schell model sources: a coherent mode representation.

We present a theory and computation method of radiation pressure from partially coherent light by establishing a coherent mode representation of the radiation forces. This is illustrated with the near field emitted from a Gaussian Schell model source, mechanically acting on a single cylinder with magnetodielectric behavior, or on a photonic molecule constituted by a pair of such cylinders. Thus after studying the force produced by a single particle, we address the effects of the spatial coherence on the bonding and antibonding states of two particles. The coherence length manifests the critical limitation of the contribution of evanescent modes to the scattered fields, and hence to the nature and strength of the electromagnetic forces, even when electric and/or magnetic partial wave resonances are excited.

Carcinoma pulmonar sarcomatoide de células gigantes. Afectación pulmonar bilateral / Young patient with pulmonary nodules

Es necesaria la investigación para realizar un diagnóstico precoz del cáncer de pulmón, así como valorar nuevas terapias en su tratamiento. Como es sabido, tiene una importante prevalencia y una elevada letalidad, ya que es la primera causa de muerte prematura en los países desarrollados. Aunque el subtipo de carcinoma sarcomatoide de pulmón es poco frecuente, la aportación de la experiencia clínica puede ayudar a conocer mejor este tipo de tumores. Por su comportamiento clínico y evolución, aún más agresivos, es fundamental que se consigan diagnósticos cada vez más precoces y unos regímenes terapéuticos más efectivos, en pro de lograr mayores tasas de curación en estos pacientes. Por este motivo, aportamos nuestra experiencia clínica con un nuevo caso con presentación bilatera (AU)

It is necessary to investigate for a best and more quickly diagnosis in lung cancer, and to evaluate new therapies, because this disease has an important prevalence and causes a high mortality rate. Lung cancer is the first cause of death in the first world. Although the subtype of sarcomatoid carcinoma is unfrequent, the clinical experience in this case can contribute to know better these tumors; for the aggressive clinical evolution, it is essential to reach a more early diagnosis and more effective treatments, for better outcomes in these patients. For these reasons, we provide our experience with a new case with bilateral presentation (AU)

Síndrome de las uñas amarillas. Presentación de un caso y revisión de la literatura / No disponible

El síndrome de uñas amarillas es una enfermedad muy poco frecuente, con alrededor de 200 casos comunicados hasta la actualidad, que se caracteriza por la presencia de dos o más de las siguientes manifestaciones: uñas amarillas, afectación pulmonar y afectación linfática con linfedema. Es una entidad poco conocida y, por lo tanto, poco diagnosticada. Por su rareza, presentamos un nuevo caso de síndrome de las uñas amarillas en un varón de 56 años de edad con bronquiectasias infectadas y mielopatía cervical (AU)

The yellow nail syndrome is a very rare disease, with about 200 cases repoted to date, which is characterized by the presence of two or more of the following manifestations: yellow nails, lung involvement and lymphatic involvement with lymphedema. It is a barely known and therefore not diagnosed. We present a new case of yellow nail syndrome in a 56 year old man with infected bronchiestasis and cervical myelopaty (AU)

Agenesia de la arteria pulmonar / No disponible

No disponible

Silicoproteinosis pulmonar. Un caso con supervivencia prolongada / Pulmonary silicoproteinosis. A case of prolonged survival

La silicoproteinosis pulmonar es una forma muy rara de la silicosis, que puede desarrollarse con un período de latencia entre pocos meses y 5 años de la primera exposición a sílice y cursa, invariablemente, con un rápido deterioro de la función pulmonar, sin respuesta eficaz a tratamiento alguno. Por su rareza y por su excepcional evolución, comunicamos el caso de una mujer de 55 años, diagnosticada en nuestro hospital de silicoproteinosis, que mejoró al retirar la exposición laboral al polvo de sílice y que permanece estable, sin empeoramiento radiológico ni de la función pulmonar 4 años después del diagnóstico de la enfermedad. En nuestro conocimiento, se trata del primer caso de silicoproteinosis que cursa con una buena evolución(AU)

Alveolar silicoproteinosis is a very rare form of silicosis that can develop after a latency period of between a few months and 5 years after the first exposure to silica, and courses invariably, with rapid deterioration of lung function, without an effective response to treatment. Because of its rarity and its unique outcome, the case is presented of a 55 year old woman, diagnosed with alveolar silicoproteinosis in our hospital, who improved by removing the occupational exposure to silica dust and remains stable with no radiological or lung function worsening four years after diagnosis of the disease. To our knowledge, this is the first case of alveolar silicoproteinosis that had a good outcome(AU)

[Pulmonary silicoproteinosis. A case of prolonged survival]. / Silicoproteinosis pulmonar. Un caso con supervivencia prolongada

Alveolar silicoproteinosis is a very rare form of silicosis that can develop after a latency period of between a few months and 5 years after the first exposure to silica, and courses invariably, with rapid deterioration of lung function, without an effective response to treatment. Because of its rarity and its unique outcome, the case is presented of a 55 year old woman, diagnosed with alveolar silicoproteinosis in our hospital, who improved by removing the occupational exposure to silica dust and remains stable with no radiological or lung function worsening four years after diagnosis of the disease. To our knowledge, this is the first case of alveolar silicoproteinosis that had a good outcome.

El coste del tabaquismo en tiempos de crisis económica / The cost of the smoking habit in times of economic crisis

No disponible

Optical forces on cylinders near subwavelength slits: effects of extraordinary transmission and excitation of Mie resonances.

We study the optical forces on particles, either dielectric or metallic, in or out their Mie resonances, near a subwavelength slit in extraordinary transmission regime. Calculations are two-dimensional, so that those particles are infinite cylinders. Illumination is with p-polarization. We show that the presence of the slit enhances by two orders of magnitude the transversal forces of optical tweezers from a beam alone. In addition, a drastically different effect of these particle resonances on the optical forces that they experience; namely, we demonstrate an enhancement of these forces, also of binding nature, at plasmon resonance wavelengths on metallic nanocylinders, whereas dielectric cylinders experience optical forces that decrease at wavelengths exciting their whispering gallery modes. Particles located at the entrance of the slit are easily bound to apertures due to the coincidence in the forward direction of scattering and gradient forces, but those particles at the exit of the slit suffer a competition between forward scattering force components and backward gradient forces which make more complex the bonding or antibonding nature of the resulting mechanical action.