ABSTRACT
We intended to estimate D.G.R. in patients suffering from GU, and CG, comparing them with healthy controls. 70 patients, divided in 3 groups, were studied; Group A (Control): 14 cases, Group B (GU) type I Johnson: 11 cases, type III Johnson: 20 cases; Group C (CG): 25 cases (11 antral and 14 antral and fundic). The following studies were performed in all of them upper digestive tract X-ray and fibro-endoscopy with multiple antral and fundic biopsies. Tc 99 HIDA 2 ml. Cu. I.V. was used as radioactive compound, and in the first hour 0.3 ml Cu. in 100 cc of water was administered orally, so as to confirm gastric topography. All patients were studied for 2 hour. Quantitative assessment of D.G.R. was expressed in % related to the hepatobiliary area. D.G.R. was detected in 7.1% of patients in Group A: 54.5% of GU type I and 70% in GU type III. In antral CG a 72.7% of D.G.R. was observed and in antral and fundic CG a 87.6% was found. The differences were significant in all the cases. D.G.R. MAGNITUDE, expressed as geometric mean, was: for Group A: 0.73%; for Group B: Ulcer type I: 6.26% and type III: 6.26%, for Group C: 6.78% in antral gastritis and 11.41% in antral and fundic gastritis.
Subject(s)
Duodenogastric Reflux/diagnostic imaging , Gastritis/physiopathology , Stomach Ulcer/physiopathology , Adult , Aged , Aged, 80 and over , Chronic Disease , Duodenogastric Reflux/complications , Female , Gastritis/complications , Humans , Imino Acids , Male , Middle Aged , Organometallic Compounds , Radionuclide Imaging , Stomach Ulcer/complications , Technetium Tc 99m LidofeninABSTRACT
We intended to estimate D.G.R. in patients suffering from GU, and CG, comparing them with healthy controls. 70 patients, divided in 3 groups, were studied; Group A (Control): 14 cases, Group B (GU) type I Johnson: 11 cases, type III Johnson: 20 cases; Group C (CG): 25 cases (11 antral and 14 antral and fundic). The following studies were performed in all of them upper digestive tract X-ray and fibro-endoscopy with multiple antral and fundic biopsies. Tc 99 HIDA 2 ml. Cu. I.V. was used as radioactive compound, and in the first hour 0.3 ml Cu. in 100 cc of water was administered orally, so as to confirm gastric topography. All patients were studied for 2 hour. Quantitative assessment of D.G.R. was expressed in
related to the hepatobiliary area. D.G.R. was detected in 7.1
of patients in Group A: 54.5
of GU type I and 70
in GU type III. In antral CG a 72.7
of D.G.R. was observed and in antral and fundic CG a 87.6
was found. The differences were significant in all the cases. D.G.R. MAGNITUDE, expressed as geometric mean, was: for Group A: 0.73
; for Group B: Ulcer type I: 6.26
and type III: 6.26
, for Group C: 6.78
in antral gastritis and 11.41
in antral and fundic gastritis.
ABSTRACT
Fifteen patients considered as "geronts" (average 70 years) have been performed Radiology, Endoscopy and Gastric Biopsies, with differents degrees of chronic gastritis as only gastric pathology, and 8 "healthy adults" (controls) were assessed on the T1/2 of gastric evacuation, with a solid meal marked with DPTA Tc 99 and measurement of isotopic activity in Gamma Camera before and after administration of a therapeutic dose of Clebopride. In the basal trial it was found that geronts gastric emptying is delayed more than controls (112 and 89 minutes). The activity of Clebopride revealed a significant decrease in both groups, being more important in geronts. This findings suggests the clinic usefulness in different pathological situations, where its useful to accelerate the time of gastric evacuation (gastric esofagic reflux, gastric ulcer) and in the geront with dispeptic symptoms and chronic gastritis related to age, as the only gastric pathology.
Subject(s)
Aged , Antiemetics/pharmacology , Benzamides/pharmacology , Gastric Emptying/drug effects , Adult , Female , Gastritis, Atrophic/physiopathology , Humans , Male , Pentetic Acid , Radionuclide Imaging , Stomach/diagnostic imagingABSTRACT
A 15 pacientes considerados "gerontes", (promedio 70 anos) a quienes se efectuo radiologia, endoscopia y biopsias gastricas, encontrandose distintos grados de gastritis cronica como unica patologia gastrica y a 8 "adultos sanos" (controles), se les evaluo el T1/2 de evacuacion gastrica,con una comida solida marcada con DTPA Tc 99 y medicion de la actividad isotopica en Camara Gamma, antes y despues de la administracion de una dosis terapeutica de clebopride. En la prueba basal se encontro que los gerontes evacuan mas tardiamente que los controles (112 y 89).La accion del clebopride revelo un descenso significativo en ambos grupos, siendo el mismo, mas importante en los gerontes.Estos hallazgos sugieren su utilidad clinica en distintas situaciones patologicas donde es util acelerar el tiempo de evacuacion gastrica (reflujo gastrico esofagico), ulcera gastrica) y en el geronte con sitomas dispepticos y gastritis cronica, vinculada a la edad como unica patologia gastrica
Subject(s)
Adult , Humans , Male , Female , Comparative Study , Antiemetics , Benzamides , Gastric Emptying , AgedABSTRACT
Fifteen patients considered as [quot ]geronts[quot ] (average 70 years) have been performed Radiology, Endoscopy and Gastric Biopsies, with differents degrees of chronic gastritis as only gastric pathology, and 8 [quot ]healthy adults[quot ] (controls) were assessed on the T1/2 of gastric evacuation, with a solid meal marked with DPTA Tc 99 and measurement of isotopic activity in Gamma Camera before and after administration of a therapeutic dose of Clebopride. In the basal trial it was found that geronts gastric emptying is delayed more than controls (112 and 89 minutes). The activity of Clebopride revealed a significant decrease in both groups, being more important in geronts. This findings suggests the clinic usefulness in different pathological situations, where its useful to accelerate the time of gastric evacuation (gastric esofagic reflux, gastric ulcer) and in the geront with dispeptic symptoms and chronic gastritis related to age, as the only gastric pathology.
ABSTRACT
A 15 pacientes considerados "gerontes", (promedio 70 anos) a quienes se efectuo radiologia, endoscopia y biopsias gastricas, encontrandose distintos grados de gastritis cronica como unica patologia gastrica y a 8 "adultos sanos" (controles), se les evaluo el T1/2 de evacuacion gastrica,con una comida solida marcada con DTPA Tc 99 y medicion de la actividad isotopica en Camara Gamma, antes y despues de la administracion de una dosis terapeutica de clebopride. En la prueba basal se encontro que los gerontes evacuan mas tardiamente que los controles (112' y 89').La accion del clebopride revelo un descenso significativo en ambos grupos, siendo el mismo, mas importante en los gerontes.Estos hallazgos sugieren su utilidad clinica en distintas situaciones patologicas donde es util acelerar el tiempo de evacuacion gastrica (reflujo gastrico esofagico), ulcera gastrica) y en el geronte con sitomas dispepticos y gastritis cronica, vinculada a la edad como unica patologia gastrica
