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Medicine (Baltimore) ; 103(3): e36804, 2024 Jan 19.
Article in English | MEDLINE | ID: mdl-38241565

ABSTRACT

BACKGROUNDS: Omega-3 supplements are endorsed for heart failure (HF) patients to reduce hospitalizations and mortality, offering anti-inflammatory and cardioprotective benefits. METHODS: A comprehensive search was conducted in various databases until November 2022. Eligible studies included clinical trials on patients with HF. Data extraction covered study details, omega-3 specifics, outcomes, and limitations. The JADAD scale was used to assess the risk of bias in randomized controlled trials. RESULTS: The review process involved 572 records from database searches, resulting in 19 studies after eliminating duplicates and screening. These studies assessed the impact of omega-3 on various clinical outcomes, such as mortality, hospitalization, cardiac function, and quality of life. Studied duration varied from weeks to years. Omega-3 supplementation demonstrated potential benefits such as improved heart function, reduced inflammation, and decreased risk of cardiovascular events. CONCLUSION: Omega-3 supplementation could benefit heart disease treatment, potentially reducing therapy duration and improving outcomes. Starting omega-3 supplementation for HF patients seems favorable.


Subject(s)
Fatty Acids, Omega-3 , Heart Diseases , Heart Failure , Humans , Clinical Trials as Topic , Dietary Supplements , Fatty Acids, Omega-3/therapeutic use , Heart Diseases/diet therapy , Heart Diseases/drug therapy , Heart Failure/diet therapy , Heart Failure/drug therapy , Quality of Life
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