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5.
Arzneimittelforschung ; 25(5): 769-71, 1975 May.
Article in English | MEDLINE | ID: mdl-1242318

ABSTRACT

The therapeutic influence of the spider Latrodectus tredecimguttatus poison on the progressive muscular dystrophy in rats caused by the method of Mendell's et al., as well as on the genetic dystrophy in mice, was examined. It was shown that the poison produces a functional and histological improvement, wheras the weight of the dystrophic muscles was not affected.


Subject(s)
Muscular Dystrophy, Animal/drug therapy , Spiders/physiology , Venoms/therapeutic use , Animals , Muscles/pathology , Muscles/physiopathology , Muscular Dystrophy, Animal/genetics , Muscular Dystrophy, Animal/physiopathology , Necrosis/pathology , Rats
6.
Neoplasma ; 22(1): 69-71, 1975.
Article in English | MEDLINE | ID: mdl-1153038

ABSTRACT

Beta-L-aspartyl-hydrazine can significantly prolong survival of the A mouse strain infected with a lymphatic leukemia sensitive to L-asparaginase. By combining the above substance with L-asparaginase even better results can be obtained.


Subject(s)
Aspartic Acid/analogs & derivatives , Hydrazines/therapeutic use , Leukemia, Lymphoid/drug therapy , Animals , Asparaginase/administration & dosage , Asparaginase/therapeutic use , Aspartic Acid/administration & dosage , Aspartic Acid/therapeutic use , Carcinoma, Ehrlich Tumor/drug therapy , Hydrazines/administration & dosage , Leukemia, Experimental , Mice , Sarcoma 180/drug therapy
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