ABSTRACT
Two young males with acne fulminans (AF) are described. In addition to severe skin lesions, they had musculoskeletal symptoms including bacteriologically negative osteolytic lesions in the clavicles. Both patients received antibiotics for suspected septic infections. The response was unsatisfactory in both patients, and combination treatment with prednisolone was started. A favourable response was observed, and a relapse occurring in the first patient was controlled by steroids alone. The possible pathomechanism of bone lesions in AF is discussed.
Subject(s)
Acne Vulgaris/complications , Osteomyelitis/complications , Prednisolone/therapeutic use , Tetracycline/therapeutic use , Adolescent , Drug Therapy, Combination , Humans , Male , Osteomyelitis/diagnostic imaging , Osteomyelitis/drug therapy , Prednisolone/administration & dosage , Radionuclide Imaging , Recurrence , Tetracycline/administration & dosageABSTRACT
Antenatal and postnatal ultrasonic findings of a case of cystic dilatation of the fourth cerebral ventricle (the Dandy-Walker syndrome) are presented. The triangular enlargement of the ventricle visualized ultrasonically was associated with mild widening of the lateral ventricles, and the finding was established postnatally by computer-assisted x-ray tomography.
Subject(s)
Dandy-Walker Syndrome/diagnosis , Hydrocephalus/diagnosis , Pregnancy Complications , Ultrasonography , Adult , Female , Humans , Infant, Newborn , Pregnancy , Prenatal Diagnosis , Tomography, X-Ray ComputedSubject(s)
Cerebral Ventricles , Echoencephalography/methods , Adolescent , Cerebellar Diseases/diagnosis , Child , Child, Preschool , Female , Humans , Hydrocephalus/diagnosis , Infant , MaleABSTRACT
A follow-up study including examinations made by a paediatrician, an ophthalmologist and a psychologist and complemented with EEG-recordings and a number of laboratory determinations was performed at the age of 3 years on 41 children who had received phototherapy during the first week of life and on 42 control children of the same age. No differences were found in growth, development, social maturity, neurological or ophthalmologic disorders, EEG-recordings or laboratory determinations between both groups. It seems unlikely that phototherapy causes any harmful longterm effects provided that the eyes are shielded.
Subject(s)
Jaundice, Neonatal/therapy , Phototherapy/adverse effects , Brain Diseases/etiology , Child Development , Child, Preschool , Electroencephalography , Eye Diseases/etiology , Female , Follow-Up Studies , Growth , Humans , Infant, Newborn , MaleABSTRACT
Significant but slight decreases in the biparietal and bitemporal diameter were observed during the first week of life with different ultrasonic methods. The lowest value was reached after two days. Between two and six days a small increase was observed in the biparietal diameter, corresponding well with the rate of growth reported for the foetal head during the last weeks of pregnancy. Reasons for these changes cannot be clarified on the basis of the present study.
