Impact Of PET/CT On Treatment In Patients With Head And Neck Squamous Cell Carcinoma.

<b><br>Introduction:</b> Although PET/CT is effective for staging HNSCC, its impact on patient management is somewhat controversial. For this reason, we considered it necessary to carry out a study in order to verify whether PET/CT helps to improve the prognosis and treatment in patients. This study was designed to address the impact of PET-FDG imaging when used alongside CT in the staging and therapeutic management of patients with HNSCC.</br> <b><br>Material and methods:</b> Data was collected from 169 patients diagnosed with HNSCC with both CT and PET/CT (performed within a maximum of 30 days of each other). It was evaluated whether discrepancies in the diagnosis of the two imaging tests had impacted the treatment.</br> <b><br>Results:</b> The combined use of CT and PET/CT led to a change in the treatment of 67 patients, who represented 39.7% of the sample. In 27.2% of cases, it entailed a change in the type of treatment which the patient received. In 3.0% of the cases, using both diagnostic tests led to modifications of the therapeutic intention of our patients.</br> <b><br>Conclusions:</b> Using PET/CT in addition to the conventional imaging method in staging resulted in more successful staging and more appropriate therapeutic decision-making.</br>.

Correlation between PET-CT and ct in the staging after the treatment of head and neck squamous cell carcinoma

Abstract Objective: The aim of this study is to find out if a single imaging test is enough to follow-up on an oncological post-treatment patient. In such a case, we would know which was more valuable after comparing the two, by CT or PET-CT. Methods: Between January 2012 and July 2018, we collected data from all patients with previous medical history who were treated with a head and neck squamous cell carcinoma in our hospital, through surgery or by using an organ preservation protocol which we had done. Patients were required to have a CT and a PET-CT performed in a maximum period of 30 days between techniques. We compared the post post-treatment stage given to each case by using only the physical examination (only the CT and the PET-CT), with the ones given by the Tumor Board. After treatment, we analysed the similarity through Cramer's V statistic test. Results: We performed a comparative analysis, obtaining a correlation of 0.426 between the stages given by the Tumor Board and the one assigned based on physical examination, without imaging techniques. By only using the computed tomography as an imaging method the correlation was 0.565, whereas with only the use of positron emission computed technology, it was estimated at 0.858. When we compared the statistical association between stages using exclusively one of the two imaging techniques, the correlation was 0.451. Conclusion: Independent of the modality, we have demonstrated that in patients who have received previous treatment, there was a higher correlation in the stages with respect to the diagnostic method conducted by the Tumor Board using PET-CT as the sole image. Level of evidence: Level 1.

Survival study in early stages of glottis cancer, stratified by treatment.

INTRODUCTION: Squamous cell carcinoma (SCC) of the vocal cord in stages I or II can be treated with radiotherapy (RT) or transoral CO2 laser microsurgery (TLM), with good oncological results. OBJECTIVES: To study the survival of patients with SCC of the vocal cord in early stages, treated with RT or TLM, in a tertiary hospital. MATERIAL AND METHODS: Disease-free survival (DFS), specific survival (SS), and overall survival (OS) were studied in patients diagnosed with stage I and II SCC of the vocal cord, for a span of 10 years of follow-up, based on sociodemographic characteristics of the patient and the primary treatment (TLM or RT). RESULTS: Both treatments achieved good survival rates. However, long-term SS was greater in patients treated with TLM compared to those treated with RT (91.7% vs. 50%, respectively, p = .001). In addition, patients treated with TLM presented a higher OS in the short term than those treated with RT (99.0% vs. 89.1%, respectively. p = .004). CONCLUSIONS AND SIGNIFICANCE: Primary treatment with TLM obtained better results than RT in the survival of patients with SCC of the vocal cord in the early stages.

Correlation between PET-CT and ct in the staging after the treatment of head and neck squamous cell carcinoma.

OBJECTIVE: The aim of this study is to find out if a single imaging test is enough to follow-up on an oncological post-treatment patient. In such a case, we would know which was more valuable after comparing the two, by CT or PET-CT. METHODS: Between January 2012 and July 2018, we collected data from all patients with previous medical history who were treated with a head and neck squamous cell carcinoma in our hospital, through surgery or by using an organ preservation protocol which we had done. Patients were required to have a CT and a PET-CT performed in a maximum period of 30 days between techniques. We compared the post post-treatment stage given to each case by using only the physical examination (only the CT and the PET-CT), with the ones given by the Tumor Board. After treatment, we analysed the similarity through Cramer's V statistic test. RESULTS: We performed a comparative analysis, obtaining a correlation of 0.426 between the stages given by the Tumor Board and the one assigned based on physical examination, without imaging techniques. By only using the computed tomography as an imaging method the correlation was 0.565, whereas with only the use of positron emission computed technology, it was estimated at 0.858. When we compared the statistical association between stages using exclusively one of the two imaging techniques, the correlation was 0.451. CONCLUSION: Independent of the modality, we have demonstrated that in patients who have received previous treatment, there was a higher correlation in the stages with respect to the diagnostic method conducted by the Tumor Board using PET-CT as the sole image. LEVEL OF EVIDENCE: Level 1.

Correlation between PET/CT and CT in the staging prior to the treatment of head and neck squamous cell carcinoma / Correlação entre PET/TC e TC no estadiamento pré tratamento do carcinoma espinocelular de cabeça e pescoço

Abstract Introduction: Head and neck squamous cell carcinoma is the seventh most common malignant tumor. The advances in treatment have improved the global survival rates in the past years, although the prognosis is still grave. Objective: The aim of the present study is to evaluate the correlation between positron emission computed tomography and computed tomography at the time of staging a previously untreated head and neck squamous cell carcinoma, and to determine which of the two imaging techniques gives us more information at the time of initial diagnosis. Methods: Data from all patients diagnosed in our hospital of head and neck squamous cell carcinoma by a biopsy of any location or unknown primary tumor was collected, between January 2012 and July 2017. In all cases, computed tomography and positron emission computed tomography were performed with a maximum of 30 days difference between them and patients had not received any prior treatment to staging. The stage given to each case was compared based solely on the physical examination, only on the computed tomography/positron emission computed tomography, with respect to the stage given by the tumor board, observing the concordance obtained through Cramer's V statistical test. Results: We performed a comparative analysis obtaining a correlation of 0.729 between the stage given by the tumor board and the one assigned based on the physical examination without imaging techniques. When only using computed tomography as an imaging method, the correlation was 0.848, whereas with only the use of positron emission computed tomography it was estimated at 0.957. When comparing the statistical association between staging using exclusively one of the two imaging techniques, correlation was 0.855. Conclusion: Positron emission computed tomography is useful for the diagnosis of head and neck squamous cell carcinoma, improving the patient's staging especially when detecting cervical and distant metastases. Therefore, we consider that the use of positron emission computed tomography for the staging of patients with head and neck squamous cell carcinoma is a diagnostic test to be considered.

Resumo Introdução: O carcinoma espinocelular de cabeça e pescoço é o sétimo tumor maligno mais comum. Os avanços no tratamento melhoraram as taxas de sobrevida global nos últimos anos, embora o prognóstico ainda seja grave. Objetivo: Avaliar a correlação entre a tomografia computadorizada por emissão de pósitrons e a tomografia computadorizada no estadiamento de carcinomas espinocelulares da cabeça e pescoço não tratados previamente e verificar qual das duas técnicas de imagem nos fornece mais informações no momento do diagnóstico inicial. Método: Os dados de todos os pacientes diagnosticados em nosso hospital com carcinoma espinocelular de cabeça e pescoço por biópsia de qualquer região ou adenopatias de origem desconhecida foram colhidos no período entre janeiro de 2012 e julho de 2017. Em todos os casos, uma tomografia computadorizada e uma tomografia computadorizada por emissão de pósitrons foram realizadas com um máximo de 30 dias de diferença entre elas. Nenhum paciente deveria ter recebido tratamento antes do estadiamento. O estadiamento atribuído a cada caso foi comparado com base apenas no exame físico, pela tomografia computadorizada ou apenas pela tomografia computadorizada por emissão de pósitrons, com relação ao estadiamento concedido pela margem tumoral, observou-se a concordância obtida pelo teste estatístico de V de Cramer. Resultado: Realizamos a análise comparativa obtendo uma correlação de 0,729 entre o estadio concedido pela margem tumoral e aquele atribuído com base no exame físico sem técnicas de imagem. Usando apenas a tomografia computadorizada como método de imagem, a correlação foi de 0,848, enquanto que a correlação com a tomografia computadorizada por emissão de pósitrons foi estimada em 0,957. Ao comparar a associação estatística entre o estadiamento usando exclusivamente uma das duas técnicas de imagem, foi de 0,855. Conclusão: Tomografia computadorizada por emissão de pósitrons é útil para o diagnóstico de carcinoma espinocelular de cabeça e pescoço, melhora o estadiamento, especialmente na detecção de metástases cervicais e à distância. Portanto, concluimos que seu uso para o estadiamento de pacientes com carcinoma espinocelular de cabeça e pescoço é um exame diagnóstico a ser considerado.

Correlation between PET/CT and CT in the staging prior to the treatment of head and neck squamous cell carcinoma.

INTRODUCTION: Head and neck squamous cell carcinoma is the seventh most common malignant tumor. The advances in treatment have improved the global survival rates in the past years, although the prognosis is still grave. OBJECTIVE: The aim of the present study is to evaluate the correlation between positron emission computed tomography and computed tomography at the time of staging a previously untreated head and neck squamous cell carcinoma, and to determine which of the two imaging techniques gives us more information at the time of initial diagnosis. METHODS: Data from all patients diagnosed in our hospital of head and neck squamous cell carcinoma by a biopsy of any location or unknown primary tumor was collected, between January 2012 and July 2017. In all cases, computed tomography and positron emission computed tomography were performed with a maximum of 30 days difference between them and patients had not received any prior treatment to staging. The stage given to each case was compared based solely on the physical examination, only on the computed tomography/positron emission computed tomography, with respect to the stage given by the tumor board, observing the concordance obtained through Cramer's V statistical test. RESULTS: We performed a comparative analysis obtaining a correlation of 0.729 between the stage given by the tumor board and the one assigned based on the physical examination without imaging techniques. When only using computed tomography as an imaging method, the correlation was 0.848, whereas with only the use of positron emission computed tomography it was estimated at 0.957. When comparing the statistical association between staging using exclusively one of the two imaging techniques, correlation was 0.855. CONCLUSION: Positron emission computed tomography is useful for the diagnosis of head and neck squamous cell carcinoma, improving the patient's staging especially when detecting cervical and distant metastases. Therefore, we consider that the use of positron emission computed tomography for the staging of patients with head and neck squamous cell carcinoma is a diagnostic test to be considered.

Radiotherapy versus laser microsurgery in the treatment of early glottic cancer.

BACKGROUND: Glottic squamous cell carcinoma (SCC) in stages I or II can be treated by transoral CO2 laser microsurgery (TLM) or exclusive radiotherapy (RT). OBJECTIVES: To compare the oncological results of patients treated with TLM, to those treated with RT, in a tertiary hospital. MATERIAL AND METHODS: Data from patients diagnosed with glottic SCC in stages I and II between 2004 and 2018 were analyzed. Response to treatment was studied in terms of recurrence, local control and laryngeal preservation. RESULTS: Of 164 patients, 63.41% received treatment with TLM and 36.58% with RT. 26.21% presented a recurrence or progression of the tumor. Both treatments obtained good local control rates (84.15% in the case of TLM and 89.6% in the case of RT) and no significant association was found between tumor recurrence and type of treatment, nor with the involvement of the anterior commissure. However, treatment with RT obtained worse laryngeal preservation rate compared to TLM (81.6% and 100% respectively) (p < .001LR). Conclusions and significance: Both treatments obtained good oncological results. There were no significant differences regarding local control. However, TLM obtained a better laryngeal preservation rate. The involvement of the anterior commissure was not a poor prognosis factor for tumor recurrence.

Enfermedad relacionada con IgG4 con afectación exclusiva nasosinusal: presentación de un caso clínico y revisión de la literatura / IgG4 related disease with exclusive sinonasal involvement: A case report and literature review

La enfermedad relacionada con IgG4 (ER-IgG4) es un proceso patológico que ha unificado un gran número de enfermedades consideradas como propias de distintos órganos cuya etiopatogenia se desconocía. Su diagnóstico se establece mediante criterios histológicos, radiológicos y serológicos. El tratamiento se basa en corticoides durante tiempo prolongado, reservándose el uso de rituximab para casos refractarios. Es extremadamente inusual que esta entidad asiente solo en cabeza y cuello sin afectación sistémica, por lo que hay pocos casos como el que presentamos descritos en la literatura. Exponemos el caso de una paciente con una tumoración orbitaria con afectación de senos paranasales, diagnosticada de ER-IgG4 nasosinusal. La precisión del diagnóstico propició el inicio precoz de tratamiento corticoideo. En la actualidad la paciente se encuentra asintomática

IgG4 related disease (igG4-RD) is a pathological process which integrates a large number of diseases of unknown pathogenesis, considered as being exclusive to many different organs. Diagnosis is established through histological, radiological and serological criteria. Treatment is based on long term corticosteroids; rituximab being used only in refractory cases. It is unusual for this entity to be found exclusively in the head and neck, without systemic involvement; there are only a few reported cases to date. We present a case of a nasosinusal IgG4-RD orbital tumor with paranasal sinus involvement. The accurate diagnosis made early onset corticosteroid treatment possible and the patient is currently asymptomatic

[IgG4 related disease with exclusive sinonasal involvement: A case report and literature review]. / Enfermedad relacionada con IgG4 con afectación exclusiva nasosinusal: presentación de un caso clínico y revisión de la literatura.

IgG4 related disease (igG4-RD) is a pathological process which integrates a large number of diseases of unknown pathogenesis, considered as being exclusive to many different organs. Diagnosis is established through histological, radiological and serological criteria. Treatment is based on long term corticosteroids; rituximab being used only in refractory cases. It is unusual for this entity to be found exclusively in the head and neck, without systemic involvement; there are only a few reported cases to date. We present a case of a nasosinusal IgG4-RD orbital tumor with paranasal sinus involvement. The accurate diagnosis made early onset corticosteroid treatment possible and the patient is currently asymptomatic.

Patient-Related Benefits for Adults with Cochlear Implantation: A Multicultural Longitudinal Observational Study.

OBJECTIVES: To assess subjectively perceived, real-world benefits longitudinally for unilateral cochlear implant (CI) recipients in a multinational population treated routinely. To identify possible predictors of self-reported benefits. DESIGN: This was a prospective, multicenter, repeated-measures study. Self-assessment of performance at preimplantation and postimplantation at 1, 2, and 3 years using standardized, validated, local language versions of the Speech, Spatial, and Qualities of Hearing Scale (SSQ), and the Health Utilities Index Mark 3 (HUI3) was performed. Outcomes were analyzed using a longitudinal mixed-effects model incorporating country effect. Patient demographics were explored for associations with change over time. SUBJECTS: Two hundred ninety-one routinely treated, unilateral CI recipients, aged 13-81 years, from 9 clinics across 4 countries. RESULTS: Highly significant improvements were observed for all outcome measures (p < 0.0001). Postimplantation, mean outcome scores remained stable beyond 1 year, with notable individual variability. A significant association for one or more outcomes with preimplantation contralateral hearing aid use, telephone use, age at implantation, implantation side, preimplantation comorbidities, dizziness, and tinnitus was observed (p < 0.004). CONCLUSIONS: Longitudinal benefits of CI treatment can be measured using clinically standardized self-assessment tools to provide a holistic view of patient-related benefits in routine clinical practice for aggregated data from multinational populations. Self-reported outcomes can provide medical-based evidence regarding CI treatment to support decision-making by health service providers.

Plasmocitoma extramedular como localización excepcional en seno frontal / Extramedullary plasmacytoma as an exceptional location in frontal sinus

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El implante coclear como tratamiento del acúfeno / The cochlear implant as a tinnitus treatment

Introducción y objetivos: El acúfeno es un síntoma de elevada prevalencia en pacientes afectados de una cocleopatía. Estudiamos la evolución del acúfeno en pacientes sometidos a implantación coclear unilateral como tratamiento de la hipoacusia profunda. Métodos: Estudio longitudinal y retrospectivo de pacientes intervenidos de implantación coclear unilateral que presentaban acúfenos bilaterales. Se ha realizado valoración cuantitativa y cualitativa de los acúfenos previo a la cirugía, y a los 6 y 12 meses de la intervención quirúrgica. Resultados: Se han valorado 20 pacientes, intervenidos de implantación coclear unilateral con un dispositivo Nucleus® CI24RE con electrodo Contour Advance TM. Durante los periodos en que el dispositivo se encontraba en funcionamiento se ha evidenciado una mejoría significativa o desaparición de los acúfenos, en el oído homolateral al implante coclear en el 65% de los pacientes, y en el oído contralateral al implante en el 50% de los pacientes. En los periodos en que el dispositivo se encontraba desconectado; se comprobó una mejoría significativa o desaparición de los acúfenos, en el oído homolateral al implante coclear en el 50% de los pacientes, y en el oído contralateral al implante en el 45% de los pacientes. En un 10% de los pacientes ha aparecido un nuevo acúfeno en el oído homolateral al implante coclear. Conclusiones: Los acúfenos bilaterales que presentaban los pacientes sometidos a implantación coclear unilateral como tratamiento de la hipoacusia profunda, han mejorado en un porcentaje elevado de los casos tanto en el oído homolateral como en el contralateral al implante (AU)

Introduction and objectives: Tinnitus is a symptom of high prevalence in patients with cochlear pathology. We studied the evolution of tinnitus in patients undergoing unilateral cochlear implantation for treatment of profound hearing loss. Methods: This was a longitudinal, retrospective study of patients that underwent unilateral cochlear implantation and who had bilateral tinnitus. Tinnitus was assessed quantitatively and qualitatively before surgery and at 6 and 12 months after surgery. Results: We evaluated 20 patients that underwent unilateral cochlear implantation with a Nucleus® CI24RE Contour Advance TM electrode device. During the periods in which the device was in operation, improvement or disappearance of tinnitus was evidenced in the ipsilateral ear in 65% of patients, and in the contralateral ear, in 50%. In periods in which the device was disconnected, improvement or disappearance of tinnitus was found in the ipsilateral ear in 50% of patients, and in the ear contralateral to the implant in 45% of the patients. In 10% of the patients, a new tinnitus appeared in the ipsilateral ear. Conclusions: The patients with profound hearing loss and bilateral tinnitus treated with unilateral cochlear implantation improved in a high percentage of cases, in the ipsilateral ear and in the contralateral ear (AU)

The cochlear implant as a tinnitus treatment.

INTRODUCTION AND OBJECTIVES: Tinnitus is a symptom of high prevalence in patients with cochlear pathology. We studied the evolution of tinnitus in patients undergoing unilateral cochlear implantation for treatment of profound hearing loss. METHODS: This was a longitudinal, retrospective study of patients that underwent unilateral cochlear implantation and who had bilateral tinnitus. Tinnitus was assessed quantitatively and qualitatively before surgery and at 6 and 12 months after surgery. RESULTS: We evaluated 20 patients that underwent unilateral cochlear implantation with a Nucleus(®) CI24RE Contour Advance™ electrode device. During the periods in which the device was in operation, improvement or disappearance of tinnitus was evidenced in the ipsilateral ear in 65% of patients, and in the contralateral ear, in 50%. In periods in which the device was disconnected, improvement or disappearance of tinnitus was found in the ipsilateral ear in 50% of patients, and in the ear contralateral to the implant in 45% of the patients. In 10% of the patients, a new tinnitus appeared in the ipsilateral ear. CONCLUSIONS: The patients with profound hearing loss and bilateral tinnitus treated with unilateral cochlear implantation improved in a high percentage of cases, in the ipsilateral ear and in the contralateral ear.

Cierre de una fístula oroantral usando cemento óseo y un colgajo de mucosa yugal / Closure of an oroantral fistula using bone cement and a jugal mucosa flap

Una fístula oroantral es una solución de continuidad patológica entre el seno maxilar y la cavidad oral, producida frecuentemente tras una extracción dentaria, en la mayoría de los casos, del primer o segundo molar. El síntoma más común que provoca es una sinusitis aguda, que evolucionará a la cronicidad si la fístula permanece. El diagnóstico se realiza mediante endoscopia transalveolar, ortopantografía o tomografía computarizada dental. Su cierre quirúrgico es necesario cuando la fístula tiene más de 3 mm, o no sella por sí misma en 3 semanas. Existen, para ello, varias técnicas, usando distintos materiales y colgajos, cuyo fin es ocluir, tanto el defecto óseo, como el mucoso, para solucionar así a la vez la fístula y el problema sinusal(AU)

The oroantral fistula is a solution of pathological continuity between the maxillary sinus and the oral cavity, frequently produced after a teeth extraction in most of cases of the first or second molars. The commonest symptom provoked is an acute sinusitis evolving to chronicity if the fistula remains. The diagnosis is made by transalveolar, orthopantography or dental computerized tomography. Its surgical closure is necessary when the fistula has more than 3 mm or not seal by itself in three weeks. For it, there are some techniques using different materials and flaps where its objective is to occlude the bone defect as well as the mucous one thus solving the fistula and the sinus problem(AU)

Utilidad del botón septal y nivel de satisfacción obtenido en los pacientes con perforaciones del septum: nuestra experiencia / Septal button utility and level of satisfaction obtained in patients with drilling septal: our experience

Introducción: La mayoría de las perforaciones septales suelen ser asintomáticas, aunque algunas pueden presentar una rinitis costrosa, obstrucción nasal, epistaxis recidivante o sibilancias nasales. Su origen es sobre todo iatrogénico o idiopático, pero también podemos encontrar otras causas. Los botones septales constituyen una solución útil por la sencillez de su colocación, siendo de elección en pacientes que no deseen una intervención quirúrgica más compleja. Objetivo: Conocer las características de las perforaciones septales, además de, realizar un estudio sobre los resultados obtenidos en la cirugía de botón septal y el nivel de satisfacción obtenido por los pacientes tras esta intervención. Material y método: Análisis retrospectivo de 22 pacientes intervenidos quirúrgicamente de colocación de botón septal entre enero de 2008 a agosto 2010 en el Hospital Clínico Universitario Lozano Blesa de Zaragoza. El análisis incluye un estudio sobre la etiología, tamaño y sintomatologia de dichas perforaciones candidatas a la utilización del botón septal. Además del análisis de la presencia o ausencia de complicaciones tras la cirugía, la evolución y la mejoría o empeoramiento posoperatorio, en cuanto a los cinco síntomas principales; obstrucción nasal, las sibilancias, las costras endonasales con sequedad, la epistaxis y la rinorrea con tres posibles respuestas; igual, mejor o peor. En el consultorio y a los tres meses de la intervención, se realiza una encuesta con una escala analógica visual (EVA), en la que el paciente realiza una puntuación subjetiva del 1 al 10 para valorar su nivel de satisfacción tras la colocación del obturador Por último se le pregunta si volvería a ponérselo. Los resultados no fueron analizados con pruebas estadísticas dado el pequeño tamaño muestral. Resultados: Nuestros pacientes han presentado una importante mejoría en síntomas como la obstrucción nasal...

Introduction: Most of the septal perforations are usually asymptomatic, although some may have a crusty rhinitis, nasal obstruction, recurrent epistaxis or nasal wheeze. Its origin is mostly iatrogenic or idiopathic but can also find other causes. Septal buttons are a useful solution for the simplicity of their placement, being of choice in patients who do not want surgery more complex. Aim: Knowing the characteristics of septal perforations, in addition, a study on the results of septal button surgery and the level of satisfaction obtained by patients after the intervention. Material and method: Retrospective analysis of 22 patients with surgical septal button surgical placement between January 2008 to August 2010 at the Hospital Clinico Universitario Lozano Blesa from Zaragoza. The analysis includes a study on the etiology, symptoms of such size and drilling candidates for the use of septal button. Besides the analysis of the presence or absence of complications after surgery, and postoperative improvement or worsening in the five main symptoms, stuffy, nose, wheezing, endonasal crust with dryness, epistaxis and rhinorrhea with three possible answers, same, better or worse. Three months after surgery in the office is conducting a survey with a visual analogue scale (VAS), in which the patient makes a subjective score of 1 to 10 to assess their level of satisfaction after the placement of the shutter. Finally asked if he would wear it. The results were analyzed with statistical tests given the small sample size. Results: Our patients have experienced a significant improvement in symptoms such as nasal obstruction and wheezing. Nasal dryness has been with worse clinical outcomes after placement of the button. Subjectively 77.2(0) percent of patients would put him back. Conclusions: The septal buttons are a therapeutic tool to keep in mind for the closure of septal perforations with good results in patients unsuitable for surgical correction.

Utilidad del material sustitutivo óseo en la cirugía del implante coclear, base de cráneo y senos paranasales: nuestra experiencia / Utility of bone replacement material in cochlear implant, skull base and sinus surgery: Our experience

Introducción: Para solucionar determinados problemas que nos surgen en la cirugía del implante coclear, de los senos paranasales y de la base de cráneo hemos introducido en nuestro servicio el uso de un cemento óseo (PolyBone®). Con el objetivo de lograr la elaboración de cementos óseos de uso quirúrgico, la unión de factores de crecimiento óseo y polifosfatos ha permitido el estudio de estos materiales biológicos. Material y resultados: Presentamos un total de 28 pacientes con edades comprendidas entre 2 y 69 años, y una edad media de 29,2 años en los que el PolyBone® nos ha servido como un arma terapéutica más en el área quirúrgica de la ORL. En dos de los pacientes (7,4%) aparecieron complicaciones. Una menor que solucionamos con tratamiento conservador y una complicación mayor, que requirió una cirugía de extracción del material y explantación del implante. En los otros 26 (92,6%) pacientes se obtuvieron excelentes resultados. Conclusiones: Existen diferentes materiales autólogos y aloplásticos que nos sirven de gran utilidad para el manejo de fístulas, relleno de cavidades, u obliteración de senos entre otros. El cirujano debe conocer las propiedades biológicas, características fundamentales, técnica de obtención y posibles aplicaciones quirúrgicas para ser capaz de prevenir futuras complicaciones. Entre estos materiales, el cemento óseo (PolyBone®) es una alternativa eficaz a tener en cuenta en el manejo quirúrgico de nuestra patología (AU)

Introduction: To solve certain problems that arise in cochlear implant, sinus and skull base surgery, the use of bone cement (PolyBone®) has been introduced in our department. With the goal of making use of surgical bone cements, combining bone growth factors and polyphosphates has allowed the study of these biological materials. Materials and Results: We present a total of 28 patients aged between 2 and 69 years (mean age of 29.2 years) in whom PolyBone® has been used as an additional therapeutic tool in the ENT surgical area. Complications occurred in 2 patients (7.4%). One was minor, solved with conservative treatment; one was a major complication that required surgery to extract the material and remove the implant. In the other 26 patients (92.6%), excellent results were achieved. Conclusions: Different autogenous and alloplastic materials are of great utility for fistula management, cavity filling or sinus obliteration, among other uses. The surgeon must understand their biological properties, fundamental characteristics, production technique and potential surgical applications to be able to prevent future complications. Among these materials, bone cement (PolyBone®) is an effective alternative that should be considered in surgical management of ENT pathology (AU)

[Utility of bone replacement material in cochlear implant, skull base and sinus surgery: our experience]. / Utilidad del material sustitutivo óseo en la cirugía del implante coclear, base de cráneo y senos paranasales: nuestra experiencia.

INTRODUCTION: To solve certain problems that arise in cochlear implant, sinus and skull base surgery, the use of bone cement (PolyBone®) has been introduced in our department. With the goal of making use of surgical bone cements, combining bone growth factors and polyphosphates has allowed the study of these biological materials. MATERIALS AND RESULTS: We present a total of 28 patients aged between 2 and 69 years (mean age of 29.2 years) in whom PolyBone® has been used as an additional therapeutic tool in the ENT surgical area. Complications occurred in 2 patients (7.4%). One was minor, solved with conservative treatment; one was a major complication that required surgery to extract the material and remove the implant. In the other 26 patients (92.6%), excellent results were achieved. CONCLUSIONS: Different autogenous and alloplastic materials are of great utility for fistula management, cavity filling or sinus obliteration, among other uses. The surgeon must understand their biological properties, fundamental characteristics, production technique and potential surgical applications to be able to prevent future complications. Among these materials, bone cement (PolyBone®) is an effective alternative that should be considered in surgical management of ENT pathology.

Evolución de la actividad mucociliar tubotimpánica, estudiada por gammagrafía, tras la colocación de tubos de ventilación en adultos con otitis media seromucosa crónica / Evolution of the tubotympanal mucociliary system activity evaluated with scintigraphy, after ventilation tube insertion in adults with chronic otitis media with effusion

Introducción y objetivos: La función mucociliar tubotimpánica está alterada en los pacientes con otitis media seromucosa. Nuestro objetivo es estudiar su situación y recuperación tras la colocación del drenaje transtimpánico. Métodos: Hemos evaluado la actividad mucociliar del oído medio y de la trompa de Eustaquio por gammagrafía, en 4 grupos de adultos con otitis media seromucosa crónica, tras la colocación del tubo de ventilación. La exploración se llevó a cabo 3 días (grupo I), 6 días (grupo II), 9 días (grupo III), y 12 días (grupo IV) tras la colocación del drenaje. Resultados: Tras excluir algunos pacientes con otorrea autolimitada, los que normalizaron la función mucociliar, resultaron ser en cada grupo: grupo I, 0 de 13, 0%; en el grupo II, 4 de 15 pacientes, 26,6%; para el grupo III: 14 de 18 casos, 88,8% y, por último, en el grupo IV, 18 de 18, 100%. Conclusiones: En los pacientes con otitis media seromucosa crónica la función mucociliar está alterada. La inserción del tubo de ventilación reestablece el aclaramiento mucociliar de forma progresiva, alcanzando la normalidad tras 12 días en todos los pacientes (AU)

Introduction and goals: Tubotympanal mucociliary function is damaged in patients with otitis media with effusion. Our objective was to study its situation and recovery after timopanostomy tube insertion. Methods: We evaluated the mucociliary activity of the ear and Eustachian tube with scintigraphy in four groups of adults with chronic otitis media with effusion after ventilation tube insertion. The test was performed on 3 days (Group I), 6 days (Group II), 9 days (Group III) and 12 days (Group IV) after tympanostomy tube insertion. Results: After excluding some patients with limited otorrhea, the percentages of patients that normalised mucociliary function in the different groups were: Group I, 0 of 13, 0%; Group II, 4 of 15 patients, 26,6%; Group III, 14 de 18 cases, 88,8%; and, in Group IV, 18 of 18, 100%. Conclusions: Mucociliary function is altered in patients with chronic otitis media with effusion. With the insertion of tympanostomy tubes, mucociliary clearance is restored progressively, reaching normal after 12 days in all the patients (AU)

[Evolution of the tubotympanal mucociliary system activity evaluated with scintigraphy, after ventilation tube insertion in adults with chronic otitis media with effusion]. / Evolución de la actividad mucociliar tubotimpánica, estudiada por gammagrafía, tras la colocación de tubos de ventilación en adultos con otitis media seromucosa crónica.

INTRODUCTION AND GOALS: Tubotympanal mucociliary function is damaged in patients with otitis media with effusion. Our objective was to study its situation and recovery after timopanostomy tube insertion. METHODS: We evaluated the mucociliary activity of the ear and Eustachian tube with scintigraphy in four groups of adults with chronic otitis media with effusion after ventilation tube insertion. The test was performed on 3 days (Group I), 6 days (Group II), 9 days (Group III) and 12 days (Group IV) after tympanostomy tube insertion. RESULTS: After excluding some patients with limited otorrhea, the percentages of patients that normalised mucociliary function in the different groups were: Group I, 0 of 13, 0%; Group II, 4 of 15 patients, 26,6%; Group III, 14 de 18 cases, 88,8%; and, in Group IV, 18 of 18, 100%. CONCLUSIONS: Mucociliary function is altered in patients with chronic otitis media with effusion. With the insertion of tympanostomy tubes, mucociliary clearance is restored progressively, reaching normal after 12 days in all the patients.