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1.
Sportverletz Sportschaden ; 21(2): 79-82, 2007 Jun.
Article in German | MEDLINE | ID: mdl-17559021

ABSTRACT

INTRODUCTION: Rehabilitation in ambulatory heart groups has become well established in comprehensive cardiac care. The prevention of injuries is critical to the safety and efficiency of the program. METHODS: Questionnaires were mailed to the ambulatory heart groups in the state of Hessen, Germany and answered by 1935/13 000 (15 %) patients (65.9 +/- 7.6 years, 1504/1935 (77.7 %) men covering approximately 674,000 patient exercise hours. RESULTS: Seventy-eight of the 106 (73.6 %) injuries reported occurred during games encompassing 28/106 (26.4 %) strains, 24/106 (22.6 %) bruises, 17/106 (16.0 %) sprains, 11/106 (10.4 %) bone fractures, 6/106 (5.7 %) ruptured tendons, 8/106 (7.5 %) ruptured muscles, 3/106 (2.8 %) ruptured ligaments, and 9/106 (8.5 %) miscellaneous. The injury risk was neither related to the cardiovascular diagnosis, the prevalence of diabetes, body mass index, previous sport experience, duration of participation in rehabilitation programs, nor to the participant's age. Patients on anticoagulants or after cardiovascular surgery had no excess risk. Gender was the only independent predictor of injuries. In men the overall incidence of injuries was higher (97/1504 [6.4 %]) than in women (9/431 [2.1 %]), p < 0.0005) while the severity was higher in women (6/9 = 66.7 % vs. 22/97 = 22.7 % p < 0.001). The injuries were treated by elastic bandages or band-aids in 69/106 (65.1 %), by splinting in 4/106 (3.8 %), by local injections in 4/106 (3.8 %), by massages in 3/106 (2.8 %), and by others in 26/106 (24.5 %). Five of the 106 (4.7 %) injuries required hospitalization. CONCLUSION: The traumatologic risk in the rehabilitation of cardiovascular outpatients is associated with a low incidence of injuries.


Subject(s)
Ambulatory Care , Athletic Injuries/epidemiology , Exercise , Heart Diseases/rehabilitation , Leisure Activities , Adult , Aged , Aged, 80 and over , Athletic Injuries/etiology , Contusions/epidemiology , Contusions/etiology , Cross-Sectional Studies , Female , Fractures, Bone/epidemiology , Fractures, Bone/etiology , Germany , Health Surveys , Heart Diseases/epidemiology , Humans , Incidence , Ligaments, Articular/injuries , Male , Middle Aged , Muscle, Skeletal/injuries , Risk , Sex Factors , Sprains and Strains/epidemiology , Sprains and Strains/etiology , Surveys and Questionnaires , Tendon Injuries/epidemiology , Tendon Injuries/etiology
2.
Cardiovasc Intervent Radiol ; 25(2): 127-32, 2002.
Article in English | MEDLINE | ID: mdl-11901431

ABSTRACT

PURPOSE: The lifelong persistence of foreign bodies within the arteries may contribute to restenosis. Thus, biodegradable devices might decrease recurrence rates. METHODS: Eleven polyhydroxybutyrate biodegradable stents and 13 tantalum stents were implanted into the iliac arteries of New Zealand white rabbits for up to 30 weeks. After killing the animals, the specimens were harvested, fixed in formalin, processed in paraffin, and stained. RESULTS: Polyhydroxybutyrate instigated intense inflammatory and proliferative reactions with an increase in collagen (2.4- to 8-fold vs native segments), thrombosis and in-stent lumen narrowing (375.5-606.6 mm vs 655.6 +/- 268.8 mm in native segments). The elastic membranes were destroyed in all specimens. The tantalum stents increased the in-stent lumen progressively (769.7 +/- 366.6 mm vs 1309.9 +/- 695.3 mm), penetrated the external elastic membrane, and increased mural collagen content (6- to 8.6-fold vs native segments). Neither restenoses nor thromboses occurred. CONCLUSIONS: In the rabbit iliac artery, polyhydroxybutyrate stents caused intensive inflammatory vascular reactions which ban them from clinical use.


Subject(s)
Iliac Artery/pathology , Iliac Artery/surgery , Polyesters/chemistry , Stents , Animals , Biopsy, Needle , Coated Materials, Biocompatible , Equipment Safety , Female , Immunohistochemistry , Models, Animal , Rabbits , Risk Assessment , Sensitivity and Specificity , Tantalum/chemistry
3.
J Invasive Cardiol ; 13(12): 774-81, 2001 Dec.
Article in English | MEDLINE | ID: mdl-11731687

ABSTRACT

PURPOSE: The trauma induced by balloon angioplasty has an impact on the outcome of coronary interventions, such as stent procedures. However, balloon inflation for PTCA is not yet standardized even though procedural and long-term outcomes might be affected. METHODS: During routine PTCA, a total of 454 patients [mean age, 60.9 +/- 9.0 years; 162 (35.7%) with 1-vessel disease; 159 (35%) with 2-vessel disease; 133 (29.3%) with 3-vessel disease] were allotted to computer-assisted dilatation (CAPS) with a pressure slope of 0.2 bar/s (CAPS 0.2; n = 149 patients), 1.0 bar/s (CAPS 1.0; n = 154 patients) or to standard inflation with a hand-driven pump (n = 151 patients). Angiographic follow-up rates after 4.1 +/- 3.2 months were 88.1% for the hand-driven pump, 94% for CAPS 0.2 and 87.7% for CAPS 1.0. RESULTS: Flow reducing (1.3-2.0%) and non-flow reducing (12.6-14.9%) dissections were equally distributed among all groups as were major adverse cardiac events (2.6-4.0%). The stent rate was 1.3% with the hand-driven pump, 0.7% with CAPS 0.2 and 1.3% with CAPS 1.0. Angiographic restenosis rate was 48.9% with the hand-driven pump, 44.3% with CAPS 0.2 and 32.6% with CAPS 1.0. (hand-driven pump versus CAPS 1.0, p < 0.007; CAPS 0.2 versus CAPS 1.0, p < 0.049). CONCLUSIONS: The pressure slope during balloon inflation in PTCA has a significant impact on restenosis. The impact on stent procedures has yet to be determined.


Subject(s)
Angioplasty, Balloon, Coronary/instrumentation , Coronary Restenosis/etiology , Adult , Aged , Aged, 80 and over , Coronary Restenosis/diagnostic imaging , Endpoint Determination , Female , Follow-Up Studies , Humans , Male , Middle Aged , Myocardial Infarction/etiology , Prospective Studies , Radiography , Recurrence , Time , Treatment Outcome
4.
Rofo ; 173(9): 836-41, 2001 Sep.
Article in German | MEDLINE | ID: mdl-11582564

ABSTRACT

OBJECTIVES: Mechanisms of restenosis after coronary stent implantation include marked intimal proliferation as well as vascular tissue protrusion through the meshes. Thus, stent sheathed with membranes may be an alternative to improve the long-term outcome. METHODS: Seventeen cylindric serpentine shaped 316L stainless steel stents (nominal diameter 3.0 mm, length 15 mm) lined and covered by a polytetrafluoroethylene (PTFE) membrane and 10 unsheathed devices were implanted into the iliac arteries of 14 New Zealand White Rabbits for an observation period of 1 - 10, 11 - 20, and 21 - 30 weeks. After sacrificing the animals, specimens were harvested, fixed in formalin, processed in paraffin, serially sliced into 5 microm thick preparations, and stained (hematoxylin & eosin, elastica von Gieson). RESULTS: The polytetrafluoroethylene membrane stents increased the vascular lumen significantly (p < 0.04) to 1185.3 - 1620.4 microm compared with the native segments (655.6 +/- 268.8 microm). In the stainless steel stents the lumen decreased from 1873.1 microm to 719.1 microm. None of the devices penetrated the internal elastic membrane. There was no inflammatory vascular reaction. Compared to the native segments, the amount of elastic fibres was slightly less (native: 8.9 %, PTFE: 2.3 - 3.5 %, without PTFE: 1.9 - 5.5 %) whereas the collagen fibres increased marginally (native: 5.1 %, PTFE: 6 - 6.9 %, without PTFE: 6.4 - 8.4 %). CONCLUSIONS: In the rabbit iliac artery, stents sheathed with a microporous polytetrafluoroethylene membrane showed good tissue compatibility with no restenosis. These results warrant clinical trials.


Subject(s)
Angioplasty, Balloon, Coronary/instrumentation , Coated Materials, Biocompatible , Models, Cardiovascular , Polytetrafluoroethylene , Stents , Animals , Equipment Failure Analysis , Humans , Iliac Artery/pathology , Muscle, Smooth, Vascular/pathology , Prosthesis Design , Rabbits
5.
Med Sci Sports Exerc ; 32(10): 1674-8, 2000 Oct.
Article in English | MEDLINE | ID: mdl-11039636

ABSTRACT

PURPOSE: Sports in cardiovascular patients (CVP) should serve for risk factor management, increase of exercise capacity, and reintegration into daily life. Competition of cardiac patients with healthy sportsmen is often discouraged and thus reintegration hampered. Golf, with its endurance component and exceptional rules (e.g., the handicap) should be an alternative. METHODS: In 20 male golfers (65.2 +/- 6.1 yr, 1.4 +/- 0.3 W x kg(-1) body weight (approximately 4.8 METs)) with cardiovascular diseases and eight controls (C) (62 +/- 5 yr, 2 +/- 0.4 W x kg(-1) body weight (approximately 6.9 METs)), the performance assessed in the laboratory (ergospirometry, serum lactate) allowed for comparison of the cardiovascular load on the golf course (lactate, Holter monitoring, blood pressure, urine catecholamines). RESULTS: In comparison with in the hospital, resting heart rates were significantly (P < 0.001) elevated in both groups immediately before the tournament (CVP: 76.1 +/- 10.8 vs 90.1 +/- 8.6 bpm; C: 74.8 +/- 6.3 vs 92.3 +/- 9.7 bpm). On the course, the mean heart rates of the patients were closer (P < 0.01) to the anaerobic threshold (105.4 +/- 11.0 vs 115.3 +/- 10.8 bpm) in comparison with controls (100.5 +/- 7.3 vs 125.6 +/- 16.6 bpm) corresponding to 0.9 +/- 0.3 W x kg(-1) (approximately 3.1 METs) or 76.0 +/- 13.1%VO2max (CVP) and to 0.9 +/- 0.2 W x kg(-1) (approximately 3.1 METs) or 55.3 +/- 9.1%VO2max (C). Serum lactate levels were 1.36 +/- 0.7 mmol x L(-1) (approximately 12.4 +/- 6.4 mg x dL(-1)) (CVP) and 1.1 +/- 0.4 mmol x L(-1) (approximately 9.1 +/- 3.6 mg x dL(-1)) (C). In patients, arrhythmias were lower in quantity and quality (LOWN) in comparison with other activities as registered by means of the 24-Holter-ECG. CONCLUSION: In cardiovascular patients, competitive golf reaches an intensity that may positively influence cardiovascular risk factors, depending on the type of the course and may provide patients the desired integration with healthy sportsmen.


Subject(s)
Cardiac Rehabilitation , Cardiovascular Diseases/physiopathology , Golf , Aged , Cardiovascular Diseases/urine , Case-Control Studies , Epinephrine/urine , Germany/epidemiology , Humans , Male , Middle Aged , Monitoring, Ambulatory , Norepinephrine/urine , Physical Endurance , Pilot Projects , Risk Factors
6.
Biomed Tech (Berl) ; 44(11): 300-7, 1999 Nov.
Article in German | MEDLINE | ID: mdl-10608073

ABSTRACT

In this report, the results of complementary studies of pressure-volume (p-V) measurements on balloon catheters with balloons of low (LC) and high compliance (HC) used for percutaneous transluminal coronary angioplasty are discussed. The measurements were performed with balloons unconfined in air (free dilatation) and also confined in different shells. In the case of rigid shells, a surprisingly high self-expansion of the catheters was found. Although this self-expansion does not contribute to the radial dilatation, it cannot be neglected, but must be taken into account when the success of balloon dilatation is determined on the basis of measured p-V curves. The investigations performed using wrapped shells clearly show the different dilatation properties of LC and HC balloons. The results provide important information on the feasibility of controlled balloon dilatation on the basis of p-V measurements performed on-line during PTCA.


Subject(s)
Angioplasty, Balloon, Coronary/instrumentation , Materials Testing , Compliance , Equipment Design , Humans , Models, Cardiovascular , Pressure
7.
Eur J Radiol ; 29(3): 273-5, 1999 Mar.
Article in English | MEDLINE | ID: mdl-10399616

ABSTRACT

Five years after open chest surgery because of three vessel coronary artery disease a patient was referred for progressing dyspnea and recent onset of atrial fibrillation. A retrocardiac mass was detected on chest X-ray and echocardiography. On CT-scan, the inhomogenous tumor made the diagnosis of a retained surgical gauze likely. Through a left incision the sponge was removed uneventfully and the dyspnea resolved.


Subject(s)
Coronary Artery Bypass , Heart Neoplasms/diagnostic imaging , Surgical Sponges , Foreign Bodies/diagnostic imaging , Humans , Male , Middle Aged , Radiography
8.
J Invasive Cardiol ; 11 Suppl B: 14B-18B, 1999 Sep.
Article in English | MEDLINE | ID: mdl-10745612

ABSTRACT

UNLABELLED: One-hundred patients undergoing routine diagnostic or interventional catheterization were randomly assigned to receive either percutaneously applied collagen (group A; n = 50) or conventional pressure dressing (group B; n = 50) for sealing of the femoral artery. Clinical variables were comparable in both groups. The heparin dose was 100 IU/kg in 30 patients and 200 IU/kg in 20 patients of either group. The average compression time was 4.3 minutes in group A and 42.3 minutes in group B (p < 0.001). Bleeding was not observed in group A but was observed in 6/50 patients in group B. The time to ambulation was 6.4 hours (range: 4-12 hours) in group A and 21.6 hours (range: 10-48 hours) in group B (p < 0.001). Hematomas with a diameter of > 6 cm developed in 4/50 patients in group A and in 11/50 patients in group B (p < 0.05). Blood transfusion or surgical interventions were not required and there was no loss of ankle pulses in either group. CONCLUSION: Percutaneously applied collagen reduced compression time and duration of bedrest after diagnostic catheterization and PTCA. Despite earlier ambulation, the incidence of bleeding was lower with collagen than with conventional pressure dressing.


Subject(s)
Angioplasty, Balloon, Coronary/adverse effects , Cardiac Catheterization/adverse effects , Hemostatic Techniques , Needlestick Injuries/therapy , Postoperative Hemorrhage/prevention & control , Aged , Bandages , Collagen/therapeutic use , Equipment and Supplies , Female , Femoral Artery/injuries , Hemostatics/therapeutic use , Humans , Male , Middle Aged , Needlestick Injuries/complications , Postoperative Hemorrhage/etiology , Pressure , Treatment Outcome
13.
Cathet Cardiovasc Diagn ; 41(4): 430-4, 1997 Aug.
Article in English | MEDLINE | ID: mdl-9258492

ABSTRACT

In a patient with proven myocardial infarction, coronary artery disease was excluded angiographically. Four weeks later the patient experienced recurrent syncope of unknown cause. By means of Holter monitoring, ST-segment elevation with subsequent first-degree AV block progressing to asystole and resulting in loss of consciousness were documented. Treatment with gallopamil and a VVI-pacemaker led to complete relief of all symptoms. Hence, Prinzmetal's angina may be a rare cause of syncope even in smooth coronary arteries.


Subject(s)
Coronary Vasospasm/complications , Heart Arrest/etiology , Syncope/etiology , Angina Pectoris, Variant/complications , Cardiac Pacing, Artificial , Coronary Angiography , Coronary Vasospasm/therapy , Electrocardiography, Ambulatory , Gallopamil/therapeutic use , Heart Arrest/physiopathology , Heart Block/complications , Humans , Male , Middle Aged , Myocardial Infarction/complications , Myocardial Infarction/diagnosis , Recurrence , Time Factors , Vasodilator Agents/therapeutic use
14.
J R Soc Med ; 90(4): 209-11, 1997 Apr.
Article in English | MEDLINE | ID: mdl-9155755

ABSTRACT

In chronic coronary occlusions the chance of successful reopening by angioplasty can be judged from the age of the occlusion. Often, however, time since occlusion cannot be accurately assessed. Therefore we determined whether the chance of reopening can be predicted from angiographic morphology. In cineangiograms from 60 consecutive patients with chronic coronary occlusions morphological details in at least two projections were evaluated in relation to the rate of success and the estimated age of occlusion. Morphological features associated with a higher rate of success (type A) were a clearcut proximal stump, absence of side branches at the site of occlusion, absence of bridging collaterals, and only slight filling of the distal part of the vessel. Features associated with a low success rate (type B) were absence of proximal stump, side branches at the site of occlusion, bridging collaterals, and rapid high-contrast filling of the distal part of the vessel. 48/60 (80%) of occlusions could be classified as type A or type B. The success rate was 17/21 (81%) in type A versus 5/27 (18.5%) in type B (P < 0.0002). The estimated age of type B occlusions was higher than that of type A medians 8 and 4 months (P < 0.002). Thus in chronic coronary occlusions the likelihood of successful reopening can be judged in many patients from morphological features.


Subject(s)
Angioplasty, Balloon, Coronary , Coronary Disease/diagnostic imaging , Coronary Disease/therapy , Chronic Disease , Cineangiography , Coronary Disease/pathology , Female , Humans , Male , Middle Aged , Prognosis , Time Factors , Treatment Outcome
15.
Int J Sports Med ; 18(1): 62-5, 1997 Jan.
Article in English | MEDLINE | ID: mdl-9059907

ABSTRACT

In outpatient rehabilitation involving cardiac patients apprehension of the rare cardiovascular complications are crucial determinants of the sports activities whereas prophylactics of injuries is thought to be less important. Retrospectively, questionnaires to specify injuries were answered by 903 patients (61.7 +/- 8 years, 753 men, 150 women from 116 coronary care groups, approximately 270,000 patient exercise hours [PEH]). Independently of the patient's age and frequency of participation 123 traumas (1 per 2,200 PEH) occurred. Ball games accounted for the majority of the injuries (101/123 = 82.1%). Overstrains and distorsions were most frequent (53.7% approximately equal to 1 per 4,100 PEH) followed by bruises/ hematomas (15.4% approximately equal to 1 per 14,200 PEH), ruptured muscles, tendons and ligaments (12.2% approximately equal to 1 per 18,000 PEH), bone fractures (11.4% approximately 1 per 19,300 PEH), and abrasions or slashes (6.5% approximately 1 per 33,750 PEH). Two of the slashes and the loss of eyesight in one patient were caused by broken spectacles. Strains and distorsions were primarily located in the upper (25/27 = 43.8%) or lower limbs (22/57 = 38.6%). All ruptured muscles, tendons and ligaments were of the lower extremities. The 14 bone fractures were localized over the body. In sports with cardiac patients physicians must focus on the cardiovascular system and stress the prophylaxis of injuries by teaching motor and technical skills as well as tactics. Non-breakable spectacles are mandatory.


Subject(s)
Athletic Injuries , Cardiac Rehabilitation , Adolescent , Adult , Aged , Aged, 80 and over , Athletic Injuries/epidemiology , Athletic Injuries/prevention & control , Child , Female , Humans , Male , Middle Aged , Outpatients , Retrospective Studies , Surveys and Questionnaires
16.
Comput Biomed Res ; 30(5): 403-13, 1997 Oct.
Article in English | MEDLINE | ID: mdl-9457440

ABSTRACT

In percutaneous balloon angioplasty the extent of trauma to the vessel as determined by slope of balloon inflation, peak pressure, and inflation time is crucial to the success of the intervention. These parameters are still not standardized and hence open to the operator. To elucidate this problem, a computer-assisted PTCA system (CAPS) was developed. CAPS is composed of a motor driven unit, a central processing and power unit, and a notebook. A syringe is clamped onto the motor unit and connected to a pressure gauge. CAPS may be linked to all types of balloon catheters. The notebook allows for preselection of peak pressure, slope of pressure increase, and inflation time. During balloon inflation, adjustments are made in a closed-loop system. On a screen, the inflation process is supervised in digital numbers and analogous curves. After the procedure, patient data and inflation curves may be recalled for analysis. In conclusion, CAPS by controlled inflation theoretically may reduce the mechanical trauma to the arteries. Further refinements should aim at gaining information on the lesions' characteristics and on the dilatation process itself.


Subject(s)
Angioplasty, Balloon, Coronary/instrumentation , Therapy, Computer-Assisted , Angioplasty, Balloon, Coronary/methods , Equipment Design , Humans , Reproducibility of Results
17.
Med Klin (Munich) ; 91(3): 131-5, 1996 Mar 15.
Article in German | MEDLINE | ID: mdl-8628198

ABSTRACT

BACKGROUND: In Israel in 1956 Gottheiner introduced outpatient rehabilitation programs in patients who had survived a myocardial infarction. In Germany one decade later these WHO phase III activities were established as well. At present any patient with cardiovascular disease is included unless suffering from acute illnesses or presenting with symptoms at rest. Gymnastics, stretching and the "historic" volleyball are completed by jogging, soccer, basketball and anaerobic exercise. Thus, a notable trauma rate would be expected especially in the elderly and those who are on anticoagulation. METHODS: A retrospective analysis evaluated questionnaires of 903 patients in 116 outpatient coronary care groups covering approximately equal to 270,000 patient exercise hours. RESULTS: 101 of 123 injuries (approximately equal to 1/2 200 patient exercise hours) occurred during games the majority of which having been distortions (53.7%), hematomas, or bruises (15.4%). Severe traumas included bone fractures (11.4%) and ruptured muscles, tendons, or ligaments (12.2%). One patient lost the sight of one eye due to a broken spectacle frame. Patients who had felt exercise as too exhausting (p < 0.001) or complained of cardiovascular symptoms (p < 0.01) showed a significantly elevated trauma rate. CONCLUSIONS: Thus, in outpatient cardiac rehabilitation the trauma rate is within the range of healthy sports men. To prevent injuries sports should be limited to the patient's level of activity. Improved skills in techniques and strategies as well as unbreakable glasses are recommended.


Subject(s)
Athletic Injuries/etiology , Cardiac Rehabilitation , Exercise , Aged , Athletic Injuries/epidemiology , Cardiovascular Diseases/drug therapy , Female , Humans , Incidence , Male , Middle Aged , Retrospective Studies
18.
Herz ; 19(3): 162-5, 1994 Jun.
Article in German | MEDLINE | ID: mdl-7927127

ABSTRACT

Today indication for percutaneous transluminal coronary angioplasty is based on typical chest pain and objective signs of myocardial ischemia during exercise. Especially in chronic coronary occlusions, however, prognostic implications may play an increasing role in the future. The case report describes long-term follow-up of a patient in whom a chronic complete occlusion of the right coronary artery could be reopened successfully back in September 1988. At this time, the peripheral part of the occluded RCA was filled retrogradely by septal collaterals from the LAD. After reopening the patient remained symptom-free for more than two years. In January 1991 again severe angina recurred and ECG showed a non-transmural anterior myocardial infarction. The LAD was occluded proximal and the peripheral part was filled retrogradely by septal collaterals coming from the right coronary artery which was still open (flow reversal). Left ventricular function was only slightly impaired and the LAD occlusion could be reopened successfully too. The case suggests that prognostic implications should be taken into consideration in addition to symptoms especially in complete coronary occlusions.


Subject(s)
Atherectomy, Coronary , Coronary Angiography , Myocardial Infarction/surgery , Aged , Collateral Circulation/physiology , Coronary Circulation/physiology , Follow-Up Studies , Humans , Male , Myocardial Infarction/diagnostic imaging , Recurrence , Reoperation , Ventricular Function, Left
19.
Presse Med ; 23(4): 164-8, 1994 Feb 05.
Article in English | MEDLINE | ID: mdl-8177858

ABSTRACT

OBJECTIVES AND METHODS: In 10 patients with peripheral arterial occlusive disease (intermittent claudication) and in 10 healthy volunteers serving as controls, muscle tissue pO2, transcutaneous pO2, arterial pO2 and rheological parameters were measured before and during breathing (for 20 min) of an oxygen reduced gas mixture simulating an altitude of about 8500 feet (2600 m, approximately 116 mm Hg pO2). Oxygen pressure values were determined by means of a polarographic method according to Ehrly and Schroeder using atraumatic micro-pt-needle electrodes. RESULTS: Tissue oxygen tension in the tibialis anterior muscle of patients with peripheral arterial occlusive disease decreased significantly from 6.5 mm Hg to 2.4 mm Hg (medians). The pooled histograms were markedly shifted to hypoxic values. The controls showed a decrease from 20.8 to 12.2 mm Hg and a strong shift to the left. Transcutaneous pO2 measured in the diseased leg decreased from 53.4 +/- 11.6 to 36.1 +/- 9.3 mm Hg (controls 57.1 +/- 9.9 to 39.7 +/- 8.9 mm Hg), arterial pO2 decreased from 80.2 +/- 15.1 to 60.0 +/- 10.4 mm Hg (controls: 86.5 +/- 16.0 to 64.7 +/- 13.6 mm Hg) and pulsoximetrically determined O2-saturation from 95.0 +/- 2.5 to 90.0 +/- 5.5% (controls: 96.1 +/- 2 to 92.0 +/- 4.2%). CONCLUSIONS: Exposure of patients with intermittent claudication to moderate altitude led to a marked decrease of tissue pO2 values in the diseased legs without any evidence of clinical worsening, especially no rest pain. It may be discussed if rest pain in ischaemic legs is due to low pO2-values or to disturbed microcirculatory perfusion.


Subject(s)
Arteritis/blood , Atmospheric Pressure , Blood Gas Monitoring, Transcutaneous/methods , Intermittent Claudication/blood , Muscles/physiology , Aged , Altitude , Arteritis/complications , Aviation , Blood Pressure Determination , Female , Humans , Intermittent Claudication/etiology , Male , Middle Aged , Reference Values , Rheology
20.
Presse Med ; 23(1): 28-31, 1994.
Article in English | MEDLINE | ID: mdl-8127812

ABSTRACT

OBJECTIVES: The risk of cardiac surgery in dialysis patients is increased compared with other patient groups. We analyzed early and long term results following various cardiac procedures. METHODS: Between 1981 and 1992, 40 patients underwent cardiac surgery with a mean age of 55.7-years (range 31-71 years). Cardiac procedures: Coronary artery bypass grafting (CABG) n = 20, aortic valve replacement (AVR) n = 6, mitral valve replacement (MVR) n = 4, AVR+CABG n = 1, MVR+CABG n = 1, AVR+MVR n = 2, combined heart and renal transplantation n = 2, atrial septal defect-closure n = 1, pericardial decortication n = 3. The preoperative NYHA functional classes were: NYHA II 5%, III 52.2%, IV 42.5%. Operative mortality was 15% (6/40). Hospital survivors were in NYHA functional classes I (3%), II (88.2%) and III (8.8%). A follow-up study was performed at 35 months (mean, range 1-93 months) postoperatively. RESULTS: There were 11 late deaths. The actuarial survival of all patients was 91% (1 year) and 69% (5 years). Following CABG it was 95% (1 year) and 72% (5 years). Survivors were in NYHA functional classes I 4.7%, II 85.8%, III 9.5%. CONCLUSION: Cardiac surgery in dialysis patients is associated with an acceptable hospital mortality. The quality of life of long term survivors is increased significantly. Thus we advocate surgical treatment in patients with symptomatic heart disease. Early diagnosis and surgical intervention in the NYHA functional class II may lead to a lower perioperative mortality.


Subject(s)
Coronary Artery Bypass/mortality , Heart Diseases/complications , Heart Valve Prosthesis/mortality , Kidney Failure, Chronic/complications , Renal Dialysis , Adult , Aged , Female , Follow-Up Studies , Heart Diseases/surgery , Heart Transplantation/mortality , Humans , Male , Middle Aged , Postoperative Complications , Risk Factors
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