ABSTRACT
Obesity and osteoporosis are both chronic conditions with multi-factor aetiologies and a considerable associated level of morbidity and mortality. They are endemic in economically developed countries. Various epidemiological studies have indicated an overweight condition to have a protective effect on the occurrence of osteoporotic fractures, but the data available on the effects of weight loss on the conservation of bone mass are scant and fragmented. The present review attempts to give a critical assessment of the published trials that have analyzed the evolution of bone mass during the administration of low calorie diets to obese females, as well as to identify those aspects that would deserve special attention in the planning of future research in this field.
Subject(s)
Body Weight/physiology , Bone Density , Obesity/therapy , Osteoporosis/prevention & control , Fractures, Spontaneous/etiology , Fractures, Spontaneous/prevention & control , Humans , Obesity/complications , Osteoporosis/complications , Risk Factors , Weight LossABSTRACT
Tanto la obesidad como la osteoporosis son enfermedades de etiología multifactorial, de curso crónico, con una importante morbi-mortalidad asociada y endémica en las sociedades económicamente desarrolladas. Diversos estudios epidemiológicos muestran un efecto protector del sobrepeso en la ocurrencia de fracturas osteoporóticas, pero la información que existe respecto a los efectos de una pérdida de peso en la conservación de la masa ósea es escasa y fraccionaria. La presente revisión pretende hacer una valoración crítica de los estudios publicados que han analizado la evolución de la masa ósea durante la administración de dietas hipocalóricas en pacientes obesas, así como identificar los aspectos que merececerían especial atención en la planificación de futuras investigaciones en este campo (AU)
Obesity and osteoporosis are both chronic conditions with multi-factor aetiologies and a considerable associated level of morbidity and mortality. They are endemic in economically developed countries. Various epidemiological studies have indicated an overweight condition to have a protective effect on the occurrence of osteoporotic fractures, but the data available on the effects of weight loss on the conservation of bone mass are scant and fragmented. The present review attempts to give a critical assessment of the published trials that have analyzed the evolution of bone mass during the administration of low calorie diets to obese females, as well as to identify those aspects that would deserve special attention in the planning of future research in this field (AU)
