[The radiation load on patients during electron x-ray scanning]. / Luchevaia nagruzka na patsientov pri élektrorentgenoskanirovanii.

Radiation exposure of critical organs and tissues to external x-ray radiation and internal irradiation from a RP was estimated on the basis of analysis of dosimetric investigations during electron x-ray scanning in 645 cancer patients. Radiation exposure of critical organs and tissues during electron x-ray scanning was shown to depend on the properties of PRs and on the location of a beam of x-ray radiation with relation to an organ. During the use of electron x-ray scanning equivalent doses exceeded doses of short-lived PRs (113mIn, 99mTc) and, on the contrary, at administration of such RPs as 75Se, 67Ga, 85Sr these doses were much lower.

[The use of 131I in the combined modality therapy of highly differentiated cancer of the thyroid gland]. / Primenenie 131I v kompleksnom lechenii vysokodifferentsirovannogo raka shchitovidnoi zhelezy.

The materials of observation over 231 patients with highly differentiated thyroid cancer were used to define indications for 131I-therapy, to specify course and summary doses taking into account side-effects of 131I. 131I-therapy is an effective method in multimodality therapy of highly differentiated thyroid cancer.

[Xeroradiographic scanning in clinical oncology]. / Elektrorentgenoskanirovanie v klinicheskoi onkologii.

A combined method of xeroradiographic scanning (ERS) was used for the recognition of tumors of different organs. Altogether 645 cancer patients were investigated: 98 with head and neck tumors, 102--with pulmonary and mediastinal tumors, 254--with liver tumors, 86--with renal tumors, 52--with bone tumors, and 53--with prostatic tumors. Special methods of investigation and tumoritropic radiopharmaceuticals 75Se-methionine, 67Ga-citrate, 85Sr, 113In, 99Tc, etc. were used. Statistical data processing was done using Olivetti computer M-24. ERS was shown to be the most effective method for the detection of cancer of the lung mediastinum (90%), head and neck (89%), and prostate (89%). The method is particularly valuable for tumors developing in anatomical regions inaccessible for examination, biopsy, and x-ray findings are not sufficiently clear. The use of ERS excludes possible errors in diagnosing disease on the edges of an organ, especially in liver and kidney investigation. The method also proved to be valuable for the assessment of therapeutic efficacy and correction of fields of irradiation.

[Electroroentgen scanning in the diagnosis of bone metastases]. / Elektrorentgenoskanirovanie v diagnostike metastazov opukholei kosti.

For diagnosis of metastatic bone pathology x-ray and radionuclide studies were combined into one: electroroentgenoscanography. A total of 48 patients with different sites of a primary tumor process were examined using 99mTc-pyrophosphate. Electroroentgenograms were obtained with the help of the Soviet ERGA-MP apparatus in the negative regimen without enlarging the scale of skeletal imaging. The scanning was done on the Scinticart and Deltronix-Nuclear units. The peculiarity o this technique is visualization of the skeleton 2-4 and 20-24 h after i.v. injection of the radioactive indicator. Bone pathology was observed in 85.4% of the cases, and the results of the roentgenoradionuclide studies were identical. In 18 out of the 41 patients visualization of the skeleton with 99mTc-pyrophosphate made it possible to specify the number of foci of pathological bone tissue transformation. In 5 patients (10.4%), secondary metastatic involvement of the skeleton was found by the radionuclide method only. The results of repeated x-ray studies of these patients over the period of 3 months were negative. Clinical-radionuclide information was the reason for revising the clinical staging of tumors and correcting therapeutic methods. The new methodological approach in the diagnosis of bone pathology: electroroentgenoscanning on the 1st and 2nd days after injection of 99mTc-pyrophosphate opens up other opportunities for diagnosing metastatic involvement of the osseous system.