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Phytother Res ; 15(3): 263-4, 2001 May.
Article in English | MEDLINE | ID: mdl-11351366

ABSTRACT

Vernonioside B2 isolated from the methanol extract of the Brazilian herb Vernonia condensata Baker was evaluated in vivo for analgesic and antiinflammatory activities. The compound reduced writhings (93.28%) and Evans blue dye diffusion (91.80%) induced by acetic acid (0.1 N) in a dose-dependent manner.


Subject(s)
Analgesics/therapeutic use , Anti-Inflammatory Agents/therapeutic use , Asteraceae , Glucosides/therapeutic use , Pain/prevention & control , Plants, Medicinal , Acetic Acid , Analgesics/pharmacology , Animals , Anti-Inflammatory Agents/pharmacology , Dose-Response Relationship, Drug , Glucosides/pharmacology , Male , Mice , Pain/chemically induced , Pain Measurement/drug effects , Plant Extracts/pharmacology , Plant Extracts/therapeutic use
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