Microlens testing on back-illuminated image sensors for space applications.

The optoelectronic properties of image sensors, among which are the photosensitivity and resolution, are key to the quality factors for imaging as well as spectrometry in Earth observation and scientific space exploration missions. Microlens arrays (MLAs) further improve state-of-the-art CMOS image sensors (CIS) by redirecting more photons into the photosensitive surface/volume of each pixel. This paper reports the design, deposition, optical characterization, and reliability assessment of such an MLA made from a UV-curable hybrid polymer and replicated on a packaged back-illuminated CIS having a pixel pitch of 15.5 µm. We find that such MLAs are highly stable to temperature variations, exposure to humidity, mechanical shocks and vibrations, as well as irradiation by gamma rays, while improving the parasitic light sensitivity by a factor of 1.8. Such MLAs can be applied on a large variety of image sensors, back-illuminated but mostly front-illuminated, with pixel pitches ranging from a few to several hundreds of micrometers, making them suitable for most specifications of the space industry.

Infections with gastrointestinal nematodes, Fasciola and Paramphistomum in cattle in Cambodia and their association with morbidity parameters.

Prevalence and seasonal variations of helminth infections and their association with morbidity parameters were studied in traditionally reared Cambodian cattle. Four villages in two provinces of West Cambodia were visited on monthly intervals over a period of 11 months, during which 2391 animals were faecal and blood sampled for parasitological and haematological examinations. The body condition score (BCS), faecal consistency (diarrhoea score, DS), colour of the ocular conjunctivae (FAMACHA(©)) and packed cell volume were determined for each individual animal. The overall proportion of samples that was positive for gastrointestinal nematodes was 52%, 44% and 37% in calves (from 1 to 6 months), young animals (6 to 24 months) and adults (over 24 months), respectively, while geometric mean faecal egg counts (FECs) for each of these age categories were 125, 66 and 15 eggs per gram, respectively. Six genera of strongyles were found in the faecal cultures, i.e. in descending order of occurrence, Cooperia, Oesophagostomum, Haemonchus, Trichostrongylus, Mecistocirrus and Bunostomum. The prevalences of Fasciola and Paramphistomum, estimated by coprological examination, varied between 5-20% and 45-95%, respectively. Logistic mixed models were used to investigate associations of morbidity markers with the presence of parasite infection. A low BCS was associated with gastrointestinal nematode and liver fluke infections, and soft faecal consistency with Paramphistomum infections. However, other factors such as nutritional deficiencies and intercurrent diseases are likely to enhance the effects of parasites and should therefore be considered when using these morbidity parameters as indicators of parasitism.

Framework model of product risk assessment.

Risk assessment has been a vital tool in the consumer product safety arena. However, the challenges have been to ensure scientific and robust assessments and to eliminate diverging risk results. Back in year 2005, EuroSafe took the initiative and orchestrated a working group (WG) on risk assessment (EuroSafe WGRA). The WG includes subject experts from regulatory bodies and industry. In the past 2 years the WG has devoted itself to vigorous research in the harmonisation of nomenclatures and the identification of basic principles of non-food consumer product risk assessment. More importantly, it has undertaken the groundbreaking work of the establishment of a risk assessment framework model. The framework model took a step-by-step approach to exemplifying a disciplined thought process: defining the objective, hazard identification and characterisation, exposure assessment, risk characterisation, risk evaluation, risk reduction and residual risk communication. The model is enriched with information source inventories and resource recommendations that can be consulted to develop practical risk assessment methods.

Assessing risks--challenges posed by the European general product safety directive.

The concept of risk appears in a prominent way in the recently revised European Directive on General Product Safety (GPSD). Risk assessment is therefore an important tool for the success of the Directive; the question is how risk assessment should be carried out in a systematic manner in order to meet the aims of the Directive. In this paper, the references in the GPSD concerning the concept of risk are reviewed and compared with reported problems in European risk assessment. Existing guidelines for risk assessment are examined in order to determine what factors determine the consistency of the outcome. This leads to recommendations for a process that could be followed in order to make risk assessment successful in the context of the GPSD. On the basis of existing guidelines for risk assessment, criteria are formulated with which methods of risk assessment should comply. A stepwise process is proposed in order to develop a common method of risk assessment that can be applied in Europe to support the GPSD. The requirements for risk management in the new GPSD are rather abstract and lack specification, both for producers and for enforcement authorities. The Directive further refers to the need to develop non-binding guidelines in due course. Sources of different outcomes of the risk assessment process are outlined in this paper as well as possibilities to achieve a more consistent basis for decision, more uniformity and transparency. These are essential conditions if one wishes to avoid both undue trade barriers and unsafe products on the market. A leading role for the European Commission seems necessary to make sure that the intentions of the GPSD are accomplished.