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1.
Bone Joint J ; 97-B(9): 1175-82, 2015 Sep.
Article in English | MEDLINE | ID: mdl-26330582

ABSTRACT

Patients from a randomised trial on resurfacing hip arthroplasty (RHA) (n = 36, 19 males; median age 57 years, 24 to 65) comparing a conventional 28 mm metal-on-metal total hip arthroplasty (MoM THA) (n = 28, 17 males; median age 59 years, 37 to 65) and a matched control group of asymptomatic patients with a 32 mm ceramic-on-polyethylene (CoP) THA (n = 33, 18 males; median age 63 years, 38 to 71) were cross-sectionally screened with metal artefact reducing sequence-MRI (MARS-MRI) for pseudotumour formation at a median of 55 months (23 to 72) post-operatively. MRIs were scored by consensus according to three different classification systems for pseudotumour formation. Clinical scores were available for all patients and metal ion levels for MoM bearing patients. Periprosthetic lesions with a median volume of 16 mL (1.5 to 35.9) were diagnosed in six patients in the RHA group (17%), one in the MoM THA group (4%) and six in the CoP group (18%). The classification systems revealed no clear differences between the groups. Solid lesions (n = 3) were exclusively encountered in the RHA group. Two patients in the RHA group and one in the MoM THA group underwent a revision for pseudotumour formation. There was no statistically significant relationship between clinical scoring, metal ion levels and periprosthetic lesions in any of the groups. Periprosthetic fluid collections are seen on MARS-MRI after conventional CoP THA and RHA and may reflect a soft-tissue collection or effusion. Currently available MRI classification systems seem to score these collections as pseudotumours, causing an-overestimatation of the incidence of pseudotumours.


Subject(s)
Arthroplasty, Replacement, Hip/adverse effects , Granuloma, Plasma Cell/etiology , Hip Joint/pathology , Hip Prosthesis/adverse effects , Metal-on-Metal Joint Prostheses/adverse effects , Adult , Aged , Arthroplasty, Replacement, Hip/instrumentation , Arthroplasty, Replacement, Hip/methods , Artifacts , Ceramics , Cross-Sectional Studies , Exudates and Transudates , Female , Granuloma, Plasma Cell/diagnosis , Humans , Magnetic Resonance Imaging/methods , Male , Middle Aged , Polyethylene , Prosthesis Design , Prosthesis Failure/etiology , Reoperation/methods , Severity of Illness Index
2.
Clin Radiol ; 69(11): 1157-64, 2014 Nov.
Article in English | MEDLINE | ID: mdl-25218253

ABSTRACT

AIM: To prospectively evaluate the influence of observer experience, consensus assessment, and abduction and external rotation (ABER) view on the diagnostic performance of magnetic resonance arthrography (MRA) in patients with traumatic anterior-shoulder instability (TASI). MATERIALS AND METHODS: Fifty-eight MRA examinations (of which 51 had additional ABER views) were assessed by six radiologists (R1-R6) and three teams (T1-T3) with different experience levels, using a seven-lesion standardized scoring form. Forty-five out of 58 MRA examination findings were surgically confirmed. Kappa coefficients, sensitivity, specificity, and differences in percent agreement or correct diagnosis (p-value, McNemar's test) were calculated per lesion and overall per seven lesion types to assess diagnostic reproducibility and accuracy. RESULTS: Overall kappa ranged from poor (k = 0.17) to moderate (k = 0.53), sensitivity from 30.6-63.5%, and specificity from 73.6-89.9%. Overall, the most experienced radiologists (R1-R2) and teams (T2-T3) agreed significantly more than the lesser experienced radiologists (R3-R4: p = 0.014, R5-R6; p = 0.018) and teams (T2-T3: p = 0.007). The most experienced radiologist (R1, R2, R3) and teams (T1, T2) were also consistently more accurate than the lesser experienced radiologists (R4, R5, R6) and team (T3). Significant differences were found between R1-R4 (p = 0.012), R3-R4 (p = 0.03), and T2-T3 (p = 0.014). The overall performance of consensus assessment was systematically higher than individual assessment. Significant differences were established between T1-T2 and radiologists R3-R4 (p<0.001, p = 0.001) and between T2 and R3 (p<0.001/p = 0.001) or R4 (p = 0.050). No overall significant differences were found between the radiologists' assessments with and without ABER. CONCLUSION: The addition of ABER does not significantly improve overall diagnostic performance. The radiologist's experience level and consensus assessment do contribute to higher reproducibility and accuracy.


Subject(s)
Clinical Competence , Consensus , Joint Instability/diagnosis , Joint Instability/physiopathology , Magnetic Resonance Imaging/methods , Radiology/standards , Shoulder Joint/physiopathology , Adolescent , Adult , Contrast Media , Female , Humans , Iohexol/analogs & derivatives , Male , Meglumine , Middle Aged , Organometallic Compounds , Prospective Studies , Reproducibility of Results , Rotation
4.
Ned Tijdschr Geneeskd ; 151(11): 642, 2007 Mar 17.
Article in Dutch | MEDLINE | ID: mdl-17441568

ABSTRACT

Patients with an atypical presentation of acute appendicitis may benefit from ancillary diagnostic imaging, especially CT. The literature shows a decrease of the number of negative appendectomies with this approach, and other causes are diagnosed in about one third of the patients. In addition, costs were reduced. Ultrasonography is a good alternative in pregnant women and in women with suspected gynaecological pathology.


Subject(s)
Appendicitis/diagnosis , Diagnostic Errors/prevention & control , Tomography, X-Ray/methods , Acute Disease , Appendicitis/diagnostic imaging , Diagnosis, Differential , Humans , Ultrasonography
5.
Circulation ; 109(17): 2092-6, 2004 May 04.
Article in English | MEDLINE | ID: mdl-15078796

ABSTRACT

BACKGROUND: Because of risk of outlet strut fracture, prophylactic replacement should be considered for Björk-Shiley convexo-concave (BScc) valve recipients. We assessed the effects of epidemiological and decision-analytic guidelines on actual BScc valve replacement. METHODS AND RESULTS: We performed a retrospective cohort study including all 2263 Dutch BScc patients with a mean follow-up of 11.3 years (range, 0 to 23 years). Outcomes were outlet strut fracture, mortality, and BScc valve replacement. For the surviving patients in 1992 (n=1330), we calculated the expected differences in life expectancy (LE) with and without BScc valve replacement according to decision guidelines developed in 1992. Differences in LE were compared with actual replacements. During 8 years of follow-up, there were 494 deaths (40%), and 11 patients had suffered outlet strut fracture. Of 1330 patients, 96 (10%) had undergone BScc valve replacement, particularly in years after introduction of initial and updated guidelines. One hundred seventeen patients (9%) had an estimated gain in LE after BScc valve replacement. These patients were more likely to undergo replacement than patients with an estimated loss of LE (hazard ratio, 6.6; 95% CI, 4.4 to 10; P<0.0001). A loss in LE after reoperation was predicted for 8 of 11 patients who experienced outlet strut fracture after guidelines were available. CONCLUSIONS: Valve replacement for BScc heart valve patients was largely in concordance with guidelines in the Netherlands. Individualized guidelines that are based on high-quality epidemiological data and are updated and implemented rigorously can influence clinical practice in complex decision problems.


Subject(s)
Decision Support Techniques , Guideline Adherence/statistics & numerical data , Heart Valve Prosthesis Implantation/statistics & numerical data , Practice Guidelines as Topic , Adult , Aged , Cause of Death , Cohort Studies , Disease-Free Survival , Emergencies , Equipment Failure , Female , Follow-Up Studies , Heart Valve Prosthesis Implantation/mortality , Humans , Life Expectancy , Male , Middle Aged , Netherlands , Reoperation/statistics & numerical data , Retrospective Studies , Survival Rate
6.
J Clin Epidemiol ; 56(10): 1006-12, 2003 Oct.
Article in English | MEDLINE | ID: mdl-14568633

ABSTRACT

BACKGROUND AND OBJECTIVE: We aimed to develop a clinical prediction rule for 30-day mortality in patients undergoing Björk-Shiley convexo-concave (BScc) valve replacement, based on primary valve implantation procedures. METHODS: We studied 30-day mortality in 2,263 patients who received a BScc valve between 1979 and 1985 in The Netherlands. A logistic regression model was constructed and internally validated with bootstrapping techniques. RESULTS: Predictors for mortality were emergency operation, coronary artery disease, mitral or double-valve replacement, BScc implant being a reoperation, endocarditis, poor left ventricular function, age, concomitant tricuspid valve plasty, and aortic root replacement. The area under the receiver operating characteristic curve (AUC) for the predicted probability of death was 0.76 (95% CI 0.72-0.80). The model calibrated well, and had adequate discriminative ability in 195 BScc valve patients who underwent explantation, including 53 prophylactic explantations (AUC 0.81, 95% CI 0.73-0.89). CONCLUSION: A prediction rule derived from BScc valve implantation data performed well in patients undergoing explantation. Because the model provides accurate individualized estimates of the risk of mortality after reoperation, it may be helpful for decision making in patients with BScc valves.


Subject(s)
Heart Valve Prosthesis Implantation/mortality , Heart Valve Prosthesis , Adult , Aged , Coronary Disease/complications , Emergencies , Follow-Up Studies , Humans , Logistic Models , Middle Aged , Models, Statistical , Netherlands/epidemiology , Prognosis , Reoperation , Risk Assessment , Risk Factors
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