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1.
Protocol based non-clinical biomedical laboratory data-collection.
O'Kane, K C; Leaders, F E; Van Hoose, M C.
Med Inform (Lond) ; 5(3): 205-13, 1980.
Article in English | MEDLINE | ID: mdl-7464347

ABSTRACT

In this paper we describe the design details of a system for protocol based non-clinical biomedical data-collection and reporting. This system permits the biomedical scientist to define one or more data-collection and analysis protocols dynamically into the system and then to cause these protocols to be executed on detached, mobile microprocessor-based work-stations. The system permits both keyboard and attached instrument data-collection as well as random animal assignment and study status reporting.


Subject(s)
Computers , Data Collection/methods , Laboratories/organization & administration , Filing , Information Systems/organization & administration , Systems Analysis
2.
Antihypertensive efficacy of metolazone (Zaroxolyn) alone and combined with reserpine in treatment of essential hypertension.
Van Hoose, M C; Cutler, R E.
Curr Ther Res Clin Exp ; 20(3): 266-76, 1976 Sep.
Article in English | MEDLINE | ID: mdl-822985

Subject(s)
Diuretics/therapeutic use , Hypertension/drug therapy , Metolazone/therapeutic use , Reserpine/therapeutic use , Adult , Aged , Blood Glucose , Blood Pressure , Body Weight , Clinical Trials as Topic , Drug Therapy, Combination , Female , Humans , Male , Metolazone/administration & dosage , Metolazone/adverse effects , Middle Aged , Placebos , Potassium/blood , Reserpine/administration & dosage , Reserpine/adverse effects
3.
The role of the cornea in the biologic response to pilocarpine.
Van Hoose, M C; Leaders, F E.
Invest Ophthalmol ; 13(5): 377-83, 1974 May.
Article in English | MEDLINE | ID: mdl-4823178

Subject(s)
Cornea/metabolism , Pilocarpine/pharmacology , Animals , Contact Lenses, Hydrophilic , Cornea/drug effects , Female , Male , Methods , Miotics/pharmacology , Pilocarpine/administration & dosage , Pilocarpine/metabolism , Pupil/drug effects , Rabbits , Time Factors
4.
The pharmacology of dl-1-(4-hydroxyphenyl)-2-isopropylamino ethanol hydrochloride, an ocular hypotensive agent in rabbits.
Leaders, F E; Fortenberry, B R; Chiang, T S; Van Hoose, M C.
Arch Int Pharmacodyn Ther ; 190(2): 368-82, 1971 Apr.
Article in English | MEDLINE | ID: mdl-5575590

Subject(s)
Amino Alcohols/therapeutic use , Antihypertensive Agents/therapeutic use , Intraocular Pressure/drug effects , Animals , Antihypertensive Agents/adverse effects , Pupil/drug effects , Rabbits
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