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1.
Acta Gastroenterol Belg ; 87(1): 37-39, 2024.
Article in English | MEDLINE | ID: mdl-38431789

ABSTRACT

Acute colitis is a common feature of infection with Shiga-toxin producing Escherichia coli (STEC) and can mimic acute severe ulcerative colitis. Early recognition is important as there is a risk of developing Shiga toxin-induced haemolytic uremic syndrome (STEC-HUS), defined by the triad of microangiopathic haemolytic anemia, thrombocytopenia and organ damage. In severe cases STEC-HUS can cause severe neurological complications and can be fatal. We present a patient with a medical history of refractory ulcerative colitis, where making the diagnosis of STEC-HUS was challenging since the initial clinical presentation was difficult to differentiate from a flare of ulcerative colitis. This case illustrates that STEC induced colitis can mimic acute severe ulcerative colitis. This finding is of utmost clinical importance because of the potential life-threatening complications of STEC-HUS. Therefore it should be excluded promptly in patients with acute severe ulcerative colitis by using multiplex-PCR assay on a faecal sample.


Subject(s)
Colitis, Ulcerative , Colitis , Escherichia coli Infections , Hemolytic-Uremic Syndrome , Shiga-Toxigenic Escherichia coli , Humans , Escherichia coli Infections/complications , Escherichia coli Infections/diagnosis , Colitis, Ulcerative/complications , Colitis, Ulcerative/diagnosis , Hemolytic-Uremic Syndrome/diagnosis , Hemolytic-Uremic Syndrome/complications , Colitis/diagnosis
2.
Acta Gastroenterol Belg ; 81(4): 534-537, 2018.
Article in English | MEDLINE | ID: mdl-30645926

ABSTRACT

Meckel's diverticulum is the most common congenital gastrointestinal malformation and may present with bleeding, obstruction and diverticulitis. Symptomatic Meckel's diverticulum is associated with age <50 years, male gender, diverticular length > 2 cm and ectopic mucosa. Formation of enteroliths is a rare complication of Meckel's diverticulum and the majority of stones will remain in the diverticulum. Factors promoting enterolith formation through precipitation of calcium in the small intestinal alkaline environment include stasis as well as diverticular anatomy and histology. Mechanical obstruction due to liberation of enteroliths is even more rare and other mechanisms include intussusception, adhesions, volvulus and neoplasms. Visualization of enteroliths on plain abdominal films is challenging because not all stones are radiopaque. Surgical diverticulectomy or segmental bowel resection with anastomosis is preferred in case of complications. We present a case of mechanical small bowel sub-obstruction resulting from an expelled Meckel's enterolith.


Subject(s)
Calculi/diagnostic imaging , Intussusception/etiology , Meckel Diverticulum/complications , Meckel Diverticulum/diagnostic imaging , Abdominal Pain/etiology , Adult , Anastomosis, Surgical/methods , Humans , Intestinal Obstruction , Intussusception/pathology , Intussusception/surgery , Male , Meckel Diverticulum/pathology
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