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2.
Am J Med Genet Suppl ; 2: 45-52, 1986.
Article in English | MEDLINE | ID: mdl-3146299

ABSTRACT

We describe a median "cleft" face anomaly (MCFA) with congenital hypothalamic hamartoma in a newborn girl. The MCFA was associated with a frontal midline skull lipoma and a complex congenital heart defect. Possible pathogenetic mechanisms are discussed, and a review of the pertinent literature is given. It is concluded that probably all malformations in our patient are disturbances of a single developmental field defect, ie, the midline.


Subject(s)
Face/abnormalities , Hamartoma/congenital , Hypothalamic Neoplasms/congenital , Brain/abnormalities , Brain/diagnostic imaging , Female , Hamartoma/pathology , Humans , Hypothalamic Neoplasms/pathology , Infant, Newborn , Radiography
3.
Br Heart J ; 54(3): 337-9, 1985 Sep.
Article in English | MEDLINE | ID: mdl-4041304

ABSTRACT

A large cardiac tumour occupying most of the right atrium and the right ventricle and causing inflow obstruction to the right heart was confirmed by cross sectional echocardiography in a 41 year old man. After surgical resection histological examination showed that the atrial tumour had the characteristics of splenic tissue. Possible mechanisms for the development of such a tumour include an origin analogous to that of an accessory spleen or the implantation and subsequent growth of lymphoid tissue in a pre-existing superior vena caval or high right atrial angioma.


Subject(s)
Choristoma/diagnosis , Heart Neoplasms/diagnosis , Spleen , Adult , Echocardiography , Heart Atria/pathology , Humans , Male
4.
Clin Neurol Neurosurg ; 87(4): 287-90, 1985.
Article in English | MEDLINE | ID: mdl-4092410

ABSTRACT

A patient is presented who developed a frontal intracerebral hemorrhage, which proved to be due to a metastasis of a choriocarcinoma. The patient's uterus and adnexa had been removed two years previously for a non-malignant disorder. two years previously for a non-malignant disorder. The authors stress the importance of cytological examination of the bloody fluid on evacuation of a hematoma.


Subject(s)
Brain Neoplasms/secondary , Cerebral Hemorrhage/pathology , Choriocarcinoma/secondary , Uterine Neoplasms/pathology , Adult , Brain Neoplasms/pathology , Cerebral Cortex/pathology , Choriocarcinoma/pathology , Female , Humans , Pregnancy , Tomography, X-Ray Computed
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