ABSTRACT
Twenty dogs with histopathologically confirmed primary (n=15) or metastatic (n=5) osteosarcoma (n=14) or fibrosarcoma (n=6) of the vertebral column were treated with surgery (n=4), radiation therapy and chemotherapy (n=6), surgery and chemotherapy (n=2), or surgery, radiation, and chemotherapy (n=8). All dogs died due to their disease; 15 died due to local failure, and five died due to nonvertebral metastasis. Overall median survival time was 135 days, with a range of 15 to 600 days. Of the factors evaluated, only postoperative neurological status had a significant influence on outcome by multivariate analysis. This study supports the overall guarded prognosis for dogs with vertebral neoplasia. Better combinations of surgery, chemotherapy, and radiation therapy remain to be defined for this difficult subset of animal cancer.
Subject(s)
Dog Diseases/mortality , Dog Diseases/therapy , Fibrosarcoma/veterinary , Osteosarcoma/veterinary , Spinal Neoplasms/veterinary , Animals , Colorado/epidemiology , Dog Diseases/pathology , Dogs , Female , Fibrosarcoma/mortality , Fibrosarcoma/therapy , Male , Osteosarcoma/mortality , Osteosarcoma/therapy , Records/veterinary , Spinal Neoplasms/mortality , Spinal Neoplasms/therapy , Survival AnalysisABSTRACT
Transcolonic portal scintigraphy was used to evaluate immediate and long-term changes in shunt blood flow after partial ligation of single extrahepatic portosystemic shunts in 8 dogs. Scintigraphy was performed before surgery, within the first 7 days after surgery, and 3 to 9 months after surgery. Shunt fraction values for this group of dogs before surgery ranged from 67 to 87% (normal reference range, < or = 15%). On the basis of postoperative scintigraphy, 4 dogs had immediate and lasting occlusion of shunt blood flow (shunt fraction, < or = 15%). One dog had a shunt fraction value within the reference range immediately after surgery, had evidence of recurrent shunt blood flow (shunt fraction, 23%) at 3 months after surgery, and again had a shunt fraction value within the reference range 9 months after surgery. Persistent, though reduced, shunt blood flow (shunt fractions, 23 and 27%) was evident immediately after surgery in 2 dogs. One of these dogs had a shunt fraction within the reference range 3 months after surgery, whereas shunt blood flow in the other dog had increased to 41%. One dog had no appreciable change in shunt blood flow immediately after surgery (shunt fraction, 70%), but the shunt fraction value had decreased to 41% at the time of the final scintigraphic examination. As assessed by transcolonic portal scintigraphy, partial single extrahepatic portosystemic ligation caused a significant decrease in mean shunt blood flow in this group of 8 dogs and resulted in eventual shunt occlusion in a majority of the dogs (6 of 8 dogs).(ABSTRACT TRUNCATED AT 250 WORDS)
Subject(s)
Dog Diseases/diagnostic imaging , Dog Diseases/surgery , Portal System/abnormalities , Animals , Congenital Abnormalities/diagnostic imaging , Congenital Abnormalities/surgery , Congenital Abnormalities/veterinary , Dogs , Female , Ligation/veterinary , Male , Portal System/diagnostic imaging , Portal System/surgery , Postoperative Care/veterinary , Preoperative Care/veterinary , Radionuclide Imaging , Regional Blood FlowABSTRACT
Middiaphyseal radial ostectomy was performed in 2 dogs that had premature closure of their distal radial physes. Complications included disuse osteoporosis, carpal hyperextension of the affected and contralateral limbs, degenerative joint disease involving the cubital and carpal joints, synostosis of the radius to the ulna, premature closure of the distal portion of the ulna, and failure to achieve normal limb length. Both dogs were lame after exercise.
