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1.
Adv Exp Med Biol ; 263: 71-6, 1990.
Article in English | MEDLINE | ID: mdl-2162132

ABSTRACT

A new 4h rapid enzyme-immunoassay for direct detection of herpes simplex virus (HSV) antigen (Du Pont Herpchek) was evaluated with 743 clinical samples collected at obstetrics and gynecology (OB/GYN), sexually transmitted diseases (STD), and ophthalmology clinics. The sensitivity and specificity of Herpchek was 98.0% and 98.4% respectively compared to virus isolation in cell culture. Confirmatory blocking ELISA tests, clinical history and follow up indicate that the true specificity of the test is 100%.


Subject(s)
Enzyme-Linked Immunosorbent Assay , Herpes Simplex/diagnosis , Simplexvirus/isolation & purification , Adult , Antigens, Viral/analysis , Cells, Cultured , Evaluation Studies as Topic , Eye Infections, Viral/diagnosis , Female , Humans , Male , Middle Aged , Predictive Value of Tests , Reagent Kits, Diagnostic , Sexually Transmitted Diseases/diagnosis
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