1.
Org Biomol Chem
; 21(13): 2816-2821, 2023 Mar 29.
Article
in English
| MEDLINE
| ID: mdl-36924392
ABSTRACT
We report here an efficient synthesis of fused bis-indazoles/indazoles via a one-pot sequential strategy starting from o-azido aldehydes and amines. This novel method involves the sequential formation of 2H-indazole followed by a Pd-catalyzed intramolecular cross-dehydrogenative coupling reaction. Overall, this one-pot sequential reaction involved the formation of new five bonds, resulting in the formation of three heterocyclic rings.