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2.
Eur J Neurol ; 24(7): 995-998, 2017 07.
Article in English | MEDLINE | ID: mdl-28544000

ABSTRACT

BACKGROUND AND PURPOSE: A Consensus document on palliative care and neurology has made recommendations on the care of people with chronic and progressive neurological disease. This study aimed to investigate whether these recommendations are understood by, acceptable to and used in practice by neurologists in Belgium. METHODS: An online survey was undertaken of 100 neurologists in Belgium, asking for their opinion on all of the recommendations in the Consensus document. RESULTS: Sixty-four of the neurologists replied. Overall, they expressed support for the recommendations, in particular open communication with patients, open assessment of patient and family needs, and discussion of dying. There was less understanding of the role of palliative care in the implementation of palliative care early in disease progression and the role of palliative care multidisciplinary teams. CONCLUSIONS: The survey shows that many of the recommendations in the European Academy of Neurology/European Association for Palliative Care Taskforce on Neurology Consensus document are understood by neurologists, and several are now seen as part of normal clinical practice. However, there is still a need to develop a more collaborative approach between neurology and palliative care services, for the benefit of patients and families.


Subject(s)
Nervous System Diseases/therapy , Neurologists , Palliative Care/standards , Belgium , Chronic Disease , Consensus , Death , Disease Progression , Europe , Family , Health Care Surveys , Patient Care Team , Surveys and Questionnaires
3.
J Neurol Sci ; 356(1-2): 19-26, 2015 Sep 15.
Article in English | MEDLINE | ID: mdl-26159625

ABSTRACT

Waldenström macroglobulinemia (WM) is a lymphoplasmacytic lymphoma characterized by the proliferation of small B-lymphocytes in the bone marrow that produce monoclonal immunoglobulin M (IgM). We describe two patients with WM who presented with neurological symptoms due to infiltration of lymphoplasmacytoid tumor cells in the central nervous system, a condition known as Bing-Neel syndrome. A literature review revealed that this syndrome is rare and commonly missed in clinical practice due to its variable presentation and a lack of awareness or knowledge. Brain and spinal magnetic resonance imaging may show a focal mass or diffuse infiltration. The diagnosis of Bing-Neel syndrome requires proof of IgM or lymphoplasmacytoid cells in cerebrospinal fluid or in a brain biopsy. Treatment with intravenous and/or intrathecal chemotherapy and cranial radiotherapy is described in literature with generally poor outcome, although a combination of these therapies seems to improve outcome. Nevertheless, insufficient data are currently available to make general treatment recommendations.


Subject(s)
Waldenstrom Macroglobulinemia/diagnosis , Waldenstrom Macroglobulinemia/immunology , Waldenstrom Macroglobulinemia/therapy , Aged , Aged, 80 and over , B-Lymphocytes/pathology , Bone Marrow/pathology , Cerebral Cortex/pathology , Drug Therapy , Female , Flow Cytometry , Humans , Hydrocephalus/etiology , Hydrocephalus/pathology , Immunoglobulin M/metabolism , Magnetic Resonance Imaging , Male , Mutation/genetics , Myeloid Differentiation Factor 88/genetics , Myeloid Differentiation Factor 88/metabolism , Radiotherapy , Spinal Cord/pathology , Waldenstrom Macroglobulinemia/genetics
4.
Neurol Sci ; 35(12): 1997-9, 2014 Dec.
Article in English | MEDLINE | ID: mdl-25139108

ABSTRACT

The most frequent complication of lumbar puncture is post lumbar puncture headache (PLPH). Recent studies confirmed that the use of atraumatic spinal needles significantly reduces the risk of PLPH. However, the majority of neurologists still use traumatic needles, possibly caused by misconceptions and beliefs about practical performance of atraumatic spinal needles. Therefore, we investigated the practical characteristics of atraumatic and traumatic spinal needles. An experimental setup with a fluid column was used with (1) a physiological NaCl 0.9 % solution and (2) a high protein content solution. Flow rates and duration of pressure measurements were measured using a traumatic needle and an atraumatic needle. The average flow rate differed less than 10 % between the two needle types with NaCl solution, and for the high protein solution the difference was even smaller. Time taken to perform accurate pressure measurements did not differ between the two needle types using NaCl 0.9 %, and was even slightly shorter for the atraumatic needle when using the high protein solution. Average flow rates and duration of pressure measurements are comparable between atraumatic spinal needles and traumatic needles. Therefore, these performance characteristics are no reason to favor traumatic needles over atraumatic needles.


Subject(s)
Needles , Spinal Puncture/instrumentation , Humans , Post-Dural Puncture Headache/etiology
5.
J Neurol Neurosurg Psychiatry ; 76(7): 1017-8, 2005 Jul.
Article in English | MEDLINE | ID: mdl-15965217

ABSTRACT

Bell's palsy is an idiopathic facial palsy of the peripheral type. A herpes virus is the most likely mechanism. We report a patient with the often encountered combination of a facial palsy with ipsilateral sensory changes. Magnetic resonance imaging showed had contrast enhancement in the greater petrosal nerve. Viral spread through anatomical connections could be an explanation for the association of facial palsy with numbness.


Subject(s)
Bell Palsy/diagnosis , Functional Laterality/physiology , Hypesthesia/diagnosis , Image Enhancement , Image Processing, Computer-Assisted , Imaging, Three-Dimensional , Magnetic Resonance Imaging , Adult , Bell Palsy/physiopathology , Bell Palsy/virology , Diagnosis, Differential , Facial Nerve/pathology , Facial Nerve/physiopathology , Facial Nerve/virology , Geniculate Ganglion/pathology , Geniculate Ganglion/physiopathology , Geniculate Ganglion/virology , Humans , Hypesthesia/physiopathology , Hypesthesia/virology , Male , Neural Conduction/physiology , Petrous Bone/pathology , Remission, Spontaneous , Sensitivity and Specificity
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