[Prevention and early diagnosis of acute pancreatitis after surgery of abdominal organs]. / Profilaktika i ranniaia diagnostika ostrogo pankreatita posle operatsii na organakh briushnoi polosti.

Of the 506 patients, operated on the abdominal organs, the clinical signs of acute postoperative pancreatitis (APP) were revealed in 28 (5.5%), stable increase of the amylase activity in the blood-- in 98 (19.4%). Systematic study of the amylase activity in the blood permits to diagnose the mild forms of APP. In high probability of the APP development, its prophylaxis should be started before the operation by means of administration of the protease inhibitors and cytostatic agents.

[Effect of trypsin and kallikrein (andecalin) on the activity of proteolytic enzymes and their inhibitors in acute experimental pancreatitis]. / Vliianie tripsina i kallikreina (andekalina) na aktivnost' proteoliticheskikh fermentov i ikh ingibitorov pri ostrom éksperimental'nom pankreatite.

Intramuscular administration of trypsin and kallikrein (andecaline) into rats contributed to more favourable development of acute traumatic pancreatitis. Trypsin and andecaline prevented the activation of proteinases in blood serum and pancreas and promoted an increase in content of trypsin inhibitor in blood serum. The proteinases efficiency appears to depend on elevation of general resistance of the organism to the trauma.