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2.
Paediatr Anaesth ; 31(12): 1350-1356, 2021 Dec.
Article in English | MEDLINE | ID: mdl-34510638

ABSTRACT

BACKGROUND: Radial artery catheterization in neonates, infants, and young children is a common and useful invasive procedure that brings technical placement challenges and potential complications due to the small diameter size of the radial artery in these patients. The aim of this study is to determine appropriate catheter sizes in infants up to 6 months of age. MATERIALS AND METHODS: A total of fifty infants undergoing general anesthesia or hospitalized in the neonatal intensive care unit were included. Images of the radial artery diameter were obtained from the infant's wrist using Philips EPIQ Diagnostic Ultrasound System CVX Release 4.0. All images obtained were distal in the forearm, medial to the border of the styloid process of the radius, at the point of maximal impulse of the radial artery, and with the wrist at a 45-degree angle position. We recorded postmenstrual age, chronological age, gender, weight, location, comorbidities, medications, weight, and vital signs of each individual. RESULTS: In this single cohort study of 50 children whose ages ranged from 0 to 6 months chronological age, their radial artery diameters were averaged proportionally to their weight and age. Use of a 22G catheter would result in 100% occlusion of the diameter of the artery in most study subjects. Use of a 24G catheter would result in a range of 75%-99% occlusion depending on weight, postmenstrual age, and chronological age of the infants. CONCLUSIONS: In view of these findings, we recommend using US to measure the diameter of the radial artery and choose the most appropriate catheter size before proceeding with US-guidance for radial artery cannulation in infants. This will prevent inappropriate sizing of the catheter and the thrombotic complications this can incur.


Subject(s)
Catheterization, Peripheral , Radial Artery , Catheters , Child , Child, Preschool , Cohort Studies , Cross-Sectional Studies , Humans , Infant , Infant, Newborn , Radial Artery/diagnostic imaging , Ultrasonography , Ultrasonography, Interventional
3.
J Investig Med High Impact Case Rep ; 9: 23247096211015025, 2021.
Article in English | MEDLINE | ID: mdl-33978500

ABSTRACT

Propionic acidemia is an inborn error of metabolism characterized by accumulation of propionic acid due to deficiency of propionyl-CoA carboxylase. Main stay of treatment focuses on reducing dietary protein. However, orthotropic liver transplantation decreases the frequency of metabolic decompensations and improves life expectancy. We report a case of a 4-year-old boy undergoing orthotropic liver transplantation to treat propionic acidemia. This case highlights the use of intraoperative monitoring of metabolic markers like urine ketones, arterial ammonia, and lactate levels as these patients are at risk for hyperammonemia and metabolic acidosis. Also, the relevance in outcomes when performing early extubation in fast-tracking recovery.


Subject(s)
Anesthetics , Liver Transplantation , Propionic Acidemia , Child , Child, Preschool , Humans , Male , Methylmalonyl-CoA Decarboxylase/genetics , Propionic Acidemia/complications
4.
Paediatr Anaesth ; 23(5): 460-2, 2013 May.
Article in English | MEDLINE | ID: mdl-23577822

ABSTRACT

In this study, we measure the radial artery internal diameter (RAID) in children up to 4 years of age before and after the induction of anesthesia. A B-mode portable color Doppler ultrasound was used to measure the RAID. Three sets of measurements were taken for each child before and after the induction of anesthesia and with the wrist in the neutral and dorsiflexed positions. The reliability of the mean value of the RAID in the three sets in 24 patients was established. There were discrepancies between the RAID and the proposed catheter size in some individuals, which may not only render placement difficult but also have potential for arterial injury. There are good reasons to measure the RAID in small children prior to insertion of an intra-arterial catheter.


Subject(s)
Radial Artery/diagnostic imaging , Ultrasonography, Interventional/methods , Age Factors , Anatomy, Cross-Sectional , Anesthesia, General , Catheterization, Peripheral/methods , Catheters , Child, Preschool , Female , Humans , Image Processing, Computer-Assisted , Infant , Male , Radial Artery/anatomy & histology , Radial Artery/growth & development , Ultrasonography, Doppler, Color
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