ABSTRACT
Presentation of results obtained in 171 evaluable patients from a series of 181, presenting surface vesical cancer in Tis, Ta and T1 stages, treated with 3 different dosages of endovesical BCG as prophylaxis for tumour relapse: a) high dose, 100 to 120 mg, 72 patients; b) intermediate dose, 20 to 50 mg, 39 patients; and, c) minidose of 1 mg, 60 patients. Complications and adverse reactions were seen to be dose-dependent, also percentage of patients free of disease both after treatment and following addition of retreatment in several patients was similar in all the dosages used. It is thus concluded that endovesical BCG 1 mg, would be an optimal dosage for the prophylaxis of surface vesical cancer relapse.
Subject(s)
BCG Vaccine/administration & dosage , Neoplasm Recurrence, Local/prevention & control , Urinary Bladder Neoplasms/prevention & control , Administration, Intravesical , Adult , Aged , Aged, 80 and over , BCG Vaccine/therapeutic use , Drug Administration Schedule , Female , Follow-Up Studies , Humans , Male , Middle Aged , Neoplasm Staging , Urinary Bladder Neoplasms/pathologySubject(s)
Aneurysm , Renal Artery , Adult , Aneurysm/diagnosis , Aneurysm/diagnostic imaging , Aneurysm/surgery , Female , Humans , Kidney Transplantation , Male , Radiography , Rupture, Spontaneous , UltrasonographyABSTRACT
114 patients were treated for urethral strictures. 54% of the strictures were of infectious origin and 46% of traumatic origin. Of the urethral plastic procedures the methods according to Turner-Warwick and Johanson have been the best. 10 of 14 operations according to the method of Turner-Warwick had good results. All 5 operations according to the method of Johanson showed good results. The best results however, were found following internal urethrotomy according to the method of Sachse. 80 patients were treated by this method and 35 were followed for more than one year. 71% had good results and an additional 26% had good results following a second procedure. We prefer the internal urethrotomy under direct vision and only when this fails we consider the open plastic procedures.
Subject(s)
Urethral Stricture/surgery , Follow-Up Studies , Humans , MethodsABSTRACT
182 patients with testicular tumors were treated since 1960. The best results from treatment of nonseminomatous germinative testicular tumors were obtained according to the following regimen: Stage A: (Tumor limited to the testis without invasion of the cord): Radical orchiectomy, lymphadenectomy, immune stimulation. Stage B1 (Invasion of the cord but less than 6 positive retroperitoneal lymph nodes): Additional triple chemotherapy with Actinomycin D, Chlorambucil and Methotrexate for 2 years. Stage B2 (More than 6 positive retroperitoneal lymph nodes): Additional radiotherapy with 4500 rads. Stage C (Distant metastases): Radical orchiectomy, retroperitoneal lymphadenectomy, immune stimulation, triple drug chemotherapy for 2 years with Actinomycin D, Methotrexate and Vincristine.
