Association between a guided meditation practice, sleep and psychological well-being in type 2 diabetes mellitus patients.

Background Type 2 diabetes mellitus [T2DM] is one of the leading causes for mortality. This study examined the role of an self-awareness based guided meditation practice, Cyclic Meditation [CM] on perceived stress, anxiety, depression, sleep and quality of life in T2DM patients. Design A single arm pre-post design was used for the study. Setting The study was conducted in an auditorium for general public diagnosed with T2DM in Ernakulam, Kerala, India. Subjects Subjects were 30 T2DM patients, both male and female of age 50.12 ± 11.15 years and BMI 25.14 ± 4.37 Kg/m2 and not having a history of hospitalisation were randomly recruited for the study following advertisements in national dailies. Intervention Participants completed a supervised CM programs in the evenings, 5 days a week for 4 weeks, in addition to their regular medication. Measures Perceived stress, anxiety and depression were assessed with Perceived Stress Scale, State Anxiety Inventory and Beck's depression inventory, respectively. Sleep and quality of life were assessed with Pittsburgh Sleep Quality Index and WHO-Quality of Life - BREF respectively. Analysis Changes in the outcome measures from baseline to 4 weeks were compared using paired "t" test. Results After 4 weeks, the quality of life and sleep scores increased 7.1% [p = 0.001] and 32.7% [p = 0.001], respectively. The perceived stress, anxiety and depression reduced 26.1% [p = 0.001], 16.01% [p = 0.003] and 37.63% [p = 0.006] as compared to their baseline reports. The CM practice also reduced daytime dysfunction. Conclusions A guided self-awareness based meditation program was safe and effective in improving depression, anxiety, perceived stress and enhance sleep and quality of life in T2DM patients, which could be helpful in reducing the future complications of T2DM. Mind management is essential along with medical management to achieve better clinical results.

Potential for Osseous Regeneration of Platelet-Rich Fibrin-A Comparative Study in Mandibular Third Molar Impaction Sockets.

PURPOSE: This study investigated the potential of platelet-rich fibrin (PRF) for osseous regeneration and soft tissue healing in mandibular third molar impaction sockets. MATERIALS AND METHODS: A prospective in vivo study was performed. Randomization was performed after extraction. On one side, the socket was sutured primarily (control site); on the other side, autologous PRF gel was placed and then the socket was sutured (test site). Postoperatively, grid periapical radiographs were obtained at periodic intervals (weeks 1, 4, and 16) and digitalized. Gray-level values were measured at 3 different regions of the socket (for regions of newly formed bone) compared with the natural bone area using HL Image++ software, and the percentage bone fill was measured. Clinical evaluation of soft tissue healing was performed using the healing index of Landry et al (J Periodontol 60:212, 1994) at the specific intervals. RESULTS: Thirty healthy men and women (age range, 18 to 35 yr) with bilaterally impacted mandibular third molars were enrolled in this study. In general, there was markedly greater bone formation in sockets treated with PRF (P < .05). In the PRF group, the average gray-level values at the cervical, middle, and apical regions were 61.85 (standard deviation [SD], ±25.186), 64.54 (SD, ±24.831), and 67.80 (SD, ±23.946), respectively, with a mean value of 64.73 (SD, ±24.411). In the control group, these values were 51.58 (SD, ±15.286), 54.30 (SD, ±16.274), and 57.53 (SD, ±16.187), respectively, with a mean of 53.67 (SD, ±16.528). The average percentage of bone fill in the PRF group was 57.90 (SD, ±26.789) and that of the non-PRF group was 46.74 (SD, ±17.713; P < .05). Soft tissue healing as evaluated by the healing index of Landry et al also was found to be better at the PRF test site and it was statistically significant (P < .05). CONCLUSIONS: There was evidence for better osseous regeneration and soft tissue healing in response to PRF. Further investigations to evaluate the application of PRF in other areas of oral and maxillofacial surgery are imperative.

A Comprehensive Proforma for Evaluation of Mandibular Third Molar Impactions.

We have developed a simple, but comprehensive proforma for evaluating mandibular third molar impactions and formulating a proper treatment plan. This proforma is aimed at residents in Oral and Maxillofacial Surgery, to help them during their initial phase, in evaluating and treating impacted mandibular third molars. This comprehensive proforma will help them to analyse third molar impactions, assess and anticipate the difficulty, judge intraoperative problems they might encounter, and evaluate the patient at post operative follow-up.