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Fiziol Zh (1994) ; 51(3): 25-31, 2005.
Article in Ukrainian | MEDLINE | ID: mdl-16108222

ABSTRACT

Fifteen participants of the Antarctic expedition (men, 27-51 years old) have been investigated after their return from a one-year stay there. All subjects have signs of latent hypoxia. Compensation of hypoxic reactions depended on the initial state of organism oxygen regimen as well as on the features of a genotype. It was supposed that, after a long stay by a person in the coastal Antarctic conditions, the latent form of hypoxia could develop. The latter was accompanied by reorganizations of oxygen regimen and determined by specific features of a genotype.


Subject(s)
Adaptation, Physiological/physiology , Hypoxia/physiopathology , Oxygen/blood , Pulmonary Gas Exchange/physiology , Adaptation, Physiological/genetics , Adult , Antarctic Regions , Blood Volume/physiology , DNA-Binding Proteins/genetics , Exercise Test , Genotype , Hemodynamics/physiology , Humans , Hypoxia/blood , Hypoxia-Inducible Factor 1 , Hypoxia-Inducible Factor 1, alpha Subunit , Male , Middle Aged , Nuclear Proteins/genetics , Oxidative Stress/physiology , Polymorphism, Genetic , Transcription Factors/genetics
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