ABSTRACT
Excessive, uncontrollable, and usually unjustified worry about certain things is a sign of the mental and behavioral disease known as generalized anxiety disorder (GAD). Genetic research suggests that numerous genes are likely implicated in the development of GAD, even if much is yet unclear about this. As a result, if someone in a family has GAD, there is a high likelihood that someone else will also suffer from the illness, as well as another anxiety disorder. Individuals with GAD are frequently overly bothered about workaday affairs like health, assets, demise, family, accord issues, or effort challenges. Worry frequently interferes with daily functioning. Excessive concern, restlessness, difficulty sleeping, tiredness, irritability, sweating, and trembling are a few symptoms that may be present. For a formal diagnosis of GAD, symptoms must be persistent for at least six months and consistent. Conversion in the amygdala's utilitarian congruence and how it processes fear and anxiety have been linked to generalized anxiety disorder. Neurotransmitters, and particularly the gamma-aminobutyric acid (GABA) variant, have long been known to cause GAD through dysregulating amygdala activity in the brain. Anxiety, concern, or physical symptoms must significantly hinder social, academic, or occupational functioning in order to qualify for a GAD diagnosis. The Diagnostic and Statistical Manual of Mental Disorders-V (DSM-V) provides explicit ethos to aid doctors in identifying this disorder. Psychological therapy based on cognitive behavioral therapy (CBT) principles is effective in reducing anxiety symptoms for short-term treatment of GAD. In this, the patient's thinking ability and methods are focused. The main principle behind CBT is that your thought patterns affect your feelings, which in turn can affect your behavior. Drugs like antidepressants, buspirone, benzodiazepines, and can all be worn to goody GAD. Outside of therapy, patients with anxiety can learn to manage it by practicing relaxation methods, reframing unfavorable ideas, and adopting stress-relieving adjustments. Being socially active and setting aside time for proper self-care are crucial components of managing generalized anxiety disorder.
ABSTRACT
The anterior cruciate ligament (ACL) is a crucial connective tissue in the knee joint (tibiofemoral joint). Although the surgical anatomy of this ligament has been studied and interpreted for decades, it remains a topic of discussion among surgeons. The ACL has two bundles, the anteromedial (AM) and the posterolateral (PL) bundle. ACL tears are among the most frequently sustained injuries to the tibiofemoral joint. The ACL is an important rotational stabilizer of the knee joint. The human knee joint can be classified as a complex structure, as it has many ligaments supporting its stability and ensuring required joint mobility. Previously, the outcomes of primary ACL surgery were poor; however, with time, the modalities have improved substantially. There are two methods of performing the reconstruction procedure, the single-bundle method, in which only the AM bundle is reconstructed, and the double-bundle method, in which both the AM and PL bundles of the ACL are reconstructed. Double bundle arthroscopic ACL reconstruction has been recognized as the gold standard procedure. The grafts used for the reconstruction procedure are the tendon of the patella graft and the grafts of the hamstrings. However, one of the drawbacks of performing this surgery is the development of complications, like osteoarthritis. This complication is observed majorly in sports professionals. This article aims to sum up the anatomy of the ACL, its regular tears, the various surgical aspects of managing it, and the advancement of treatment options in the past centuries. Although much has been achieved, detailed scientific studies should be carried out to improve the prognosis and decrease the risk of development of complications.
ABSTRACT
The definition of geriatrics is very complex to explain though it can be written as the treatment and care provided by healthcare and medical systems primarily to more venerable and senior citizens group of the population. The age group considered to be entering the old group is believed to be those who have reached their sixth decade of life. However, most of the global geriatric population doesn't need treatment until their seventh decade. Bodily impairment, both physical and mental, due to various reasons, for example, financial or personal reasons or feeling ignored, is reasonable for clinicians to anticipate caring for a growing proportion of older patients with complicated medical and psychosocial concerns. Complex ethical quandaries could develop as a result of these difficulties and problems. Who should anticipate ethical challenges faced by doctors early during management? We offer practical recommendations for improving communication because ineffective patient-clinician communication might result in moral dilemmas. Physical impairment, hopelessness, and cognitive decline are all more prevalent as people age. Politicians and healthcare providers of nations should step in to search for a measure to reduce the uprising of the condition; otherwise, it will lead to an uprising of the cases in an exponential manner. It is necessary to increase the financial challenges faced by the elderly. In addition, awareness should be increased, as well as programs aimed at enhancing their standard of living.
ABSTRACT
Whole-body vibration therapy is an intentional biomechanical stimulation of the body using various frequencies of vibrations with the motive of health improvement. Ever since its discovery, this therapy has been extensively used in physiotherapeutic measures and the sports industry. For its property of increasing bone mass and density, space agencies use this therapy on astronauts who return to Earth after long-term space missions to regain lost bone and muscle mass. The potential of this therapy to restore bone mass encouraged researchers to look for its scope in the treatment of age-related bone degenerative diseases such as osteoporosis and sarcopenia, as well as in the correction of posture control and gait in geriatrics and post-menopausal women. Osteoporosis and osteopenia account for roughly half of all fractures worldwide. These degenerative diseases also cause gait and posture changes. Bisphosphonates, monoclonal antibodies, parathyroid hormone fragments, hormone replacement therapies, and calcium and vitamin D supplementation are among the medical treatments available. Lifestyle changes and physical exercise are advised. However, vibration therapy's scope as a treatment option is yet to be explored. The safe range of frequency, amplitude, duration, and intensity of the therapy is still to be determined. This article is a review of the results of various clinical trials done in the last 10 years that target the effect of vibration therapy in both osteoporotic women and the elderly for the treatment of such ailments and deformities. We collected data from PubMed using advanced search and applied the exclusion criteria. In total, we analyzed nine clinical trials.
ABSTRACT
Virtual reality is a novel approach for distracting and alleviating anxiety, pain, and other complications during medical procedures, and it can be more effective than conventional methods. In virtual reality, the patient is completely immersed in the virtual environment, which is used to make patients feel more comfortable and can provide a positive prognosis. The data were searched by using the Boolean operator "AND" between the search phrases "Virtual reality," and "Pediatrics" and the relevant literature was extracted. The inclusion criteria were the free full text, randomized controlled trials, studies between 2016 and 2022 and pediatric patients. This systematic review was conducted to compare randomized controlled trials of virtual reality applications in pediatric patients in different clinical settings. Of the included 15 randomized controlled trials, 12 studies were on pain and anxiety, two on brain injury and cerebral palsy, and one on awareness among asthmatic patients. This review concluded that virtual reality exposure has a beneficial effect on pediatric patients in reducing pain and anxiety, improving muscle strength and dexterity, and awareness among asthmatic patients.
ABSTRACT
In today's world, progressively enormous popularity prevails around artificial intelligence (AI). AI is gaining popularity in the identification of various images. Therefore, it has been widely used in the ultrasound of the breast. Furthermore, AI can perform a quantitative evaluation, which further helps maintain the diagnosis's accuracy. Moreover, breast cancer is the most common cancer in women, posing a severe threat to women's health. Hence, its early detection is usually associated with a patient's prognosis. As a result, using AI in breast cancer screening and detection is highly crucial. The concept of AI in the perspective of breast ultrasound has been highlighted in this brief review article. It tends to focus on early AI, i.e., traditional machine learning and deep learning algorithms. Also, the use of AI in ultrasound and the use of it in mammography, magnetic resonance imaging, nuclear medicine imaging, and classification of breast lesions is broadly explained, along with the challenges faced in bringing AI into daily practice.
ABSTRACT
Dengue is a viral infection caused by the arboviridae family of viruses and is transmitted by the vector, a mosquito with the scientific name Aedes egyptii. The fever caused by the Dengue virus is best labelled as Break Bone fever because of the severe myalgia that accompanies the infection. Snakebite is also a global health problem. Mostly seen in tropical countries and countries with agriculture as the backbone of the economy, it has a varied presentation in such extremes that it can go from a very mild course of disease not requiring antidote administration to life-threatening complications of respiratory muscles paralysis, coagulopathy, and rhabdomyolysis leading to acute kidney injury based on the nature of the venom of the snake. Here, we report a case of snakebite who was also battling a concurrent Dengue infection thus complicating the management of the patient.
